Assessment
Questionnaire

Have a symptom?
See what questions
a doctor would ask.
 
Diseases » Acanthosis nigricans » Glossary
 

Glossary for Acanthosis nigricans

  • Acquired total lipodystrophy: A rare acquired disorder that involves adipose tissue abnormalities and is characterized by loss of adipose tissue through the body. The disorder is very similar to the congenital form but the liver involvement is more severe.
  • Acromegaly: A hormonal disorder involving excess growth hormone production by the pituitary gland.
  • Beare-Stevenson cutis gyrata syndrome: A rare genetic disorder involving skin and skull abnormalities due to the premature fusion of skull bones.
  • Berardinelli-Seip congenital lipodystrophy: A rare genetic disorder characterized by diabetes mellitus, loss of body fat, hepatomegaly, enlarged genitals, increased skeletal growth and other abnormalities.
  • Berardinelli-Seip congenital lipodystrophy, type 1: A rare genetic disorder characterized by early-onset diabetes mellitus, loss of body fat, serious insulin resistance, high blood triglycerides and fatty liver. Type 1 is distinguished from type 2 by the origin of the genetic defect. Type 1 is caused by a defect on the AGPAT2 gene on chromosome 9q34.3. Type 1 seems to be less severe with some cases of type 2 resulting in premature death which can occur as early as the first year of life. Type 2 also involves mental retardation which is not seen in type 1.
  • Berardinelli-Seip congenital lipodystrophy, type 2: A rare genetic disorder characterized by early-onset diabetes mellitus, loss of body fat, serious insulin resistance, high blood triglycerides and fatty liver. Type 2 is distinguished from type 2 by the origin of the genetic defect. Type 2 is caused by a defect on the BSCL2 gene on chromosome 11q13. Type 2 seems to be more severe with some cases resulting in premature death which can occur as early as the first year of life. Type 2 also involves mental retardation which is not seen in type 1.
  • Bloom Syndrome: A rare genetic inherited genetic disorder which mainly affects Ashkenazic Jewish people and is characterized by short stature, malar hypoplasia, and a telangiectatic erythema of the face.
  • Cardiofaciocutaneous Syndrome: A rare genetic disorder characterized by short stature, congenital heart defects skin anomalies and frontal bossing.
  • Congenital partial lipodystrophy: A rare congenital disorder that involves adipose tissue abnormalities and is characterized by loss of adipose tissue mainly in the trunk and limbs.
  • Costello syndrome: A rare genetic disorder characterized by papillomas which may become malignant.
  • Crouzonodermoskeletal syndrome: A rare disorder characterized by the premature jointing of the skull bones as well as acanthosis nigricans which is a skin condition.
  • Cushing's disease: A condition of hyperadrenocorticism which is secondary to excessive pituitary secretion of ACTH. Cushing's disease is different to Cushing's syndrome which refers to the effects of glucocorticoid excess from any cause.
  • Diabetes: Failing or reduced ability of the body to handle sugars.
  • HAIR-AN Syndrome: A very rare syndrome that affects females only and is characterized mainly by insulin resistance, dark velvety patches of skin and increased male hormone production in females.
  • Hyperandrogenism: Excessive levels of androgen (male sex hormones) that can occur in males and females.
  • Hyperpigmentation: Excess skin pigment or coloration
  • Hyperthyroidism: Too much thyroid hormone production.
  • Hypothyroidism: Too little thyroid hormone production.
  • Insulin Resistance: The resistance of the body to insulin
  • Insulin resistance, short fifth metacarpals: A rare syndrome characterized by short fifth fingers and fifth hand bones as well as insulin resistance.
  • Insulin-resistance syndrome, type A: A syndrome characterized by insulin resistance resulting in distinctive skin lesions called acanthosis nigricans. It is the least severe form of insulin resistance.
  • Insulin-resistance type B: A very rare syndrome where insulin resistance is associated with autoimmune disease. The disorder is caused by antibodies which attack the bodies insulin receptors.
  • Insulin-resistant acanthosis nigricans, type A: A patch of velvety, pigmented skin that occurs in association with insulin-resistant diabetes mellitus.
  • Lawrence-Seip syndrome: Lawrence-Seip syndrome is a relatively uncommon condition involving generalized loss of skin fat that is acquired rather than congenital as in Berardinelli-Seip Syndrome. Patients can also develop diabetes mellitus and other problems. The loss of skin fat tends to occur during childhood or adolescence and is often triggered by infections such as measles and hepatitis. The diabetes tends to occur after fat loss begins. The limbs and face tend to be the most affected.
  • Leprechaunism: A very rare genetic disorder characterized by insulin resistance which leads to growth delay and endocrine system abnormalities.
  • Lipodystrophy, familial partial, due to AKT2 mutations: An inherited disorder characterized by the loss of fatty tissue from the extremities while fatty tissue on the face, neck and trunk is normal or increased.
  • Lipodystrophy, familial partial, type 1 (FPLD1): An inherited disorder characterized by the loss of fatty tissue from the extremities while fatty tissue on the face, neck and trunk is normal or increased.
  • Lipodystrophy, familial partial, type 3 (FPLD3): A rare metabolic disorder involving abnormal fat gradually disappears from the limbs, trunk and buttocks but stays the same or accumulates on areas such as the face, shoulders, neck and genitals.
  • Melanoma: Melanoma is the most dangerous type of skin cancer. It is the leading cause of death from skin disease. It involves cells called melanocytes, which produce a skin pigment called melanin. Melanin is responsible for skin and hair color.
  • Miescher syndrome (2): A rare inherited disorder characterized by pigmented velvety patches of skin, excess body hair, failure to thrive, retarded growth, diabetes and facial abnormalities.
  • Pancreatic cancer: Pancreatic cancer is a malignant neoplasm of the pancreas
  • Polycystic ovary syndrome: Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects approximately 5% of all women.
  • Rabson-Mendenhall syndrome: A very rare genetic disorder involving severe insulin resistance which is where the body fails to be able to use insulin which is needed to control blood sugar levels.
  • Retinis pigmentosa -- deafness -- hypogenitalism: A very rare syndrome characterized mainly by progressive retinal damage, deafness and genital anomalies.
  • Severe achondroplasia with developmental delay and acanthosis nigricans: A very rare inherited disorder characterized by abnormal bone development and brain and skin abnormalities.
  • Skin conditions: Any condition that affects the skin
  • Stomach cancer: Stomach or gastric cancer can develop in any part of the stomach and may spread throughout the stomach and to other organs
  • Tretinoin -- Teratogenic Agent: There is evidence to indicate that exposure to Tretinoin during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Type 2 diabetes: Most common diabetes in adults, usually progressing slowly, mostly treated without insulin at diagnosis.

 

By using this site you agree to our Terms of Use. Information provided on this site is for informational purposes only; it is not intended as a substitute for advice from your own medical team. The information on this site is not to be used for diagnosing or treating any health concerns you may have - please contact your physician or health care professional for all your medical needs. Please see our Terms of Use.

Home | Symptoms | Diseases | Diagnosis | Videos | Tools | Forum | About Us | Terms of Use | Privacy Policy | Site Map | Advertise