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Diseases » Aflatoxicosis » Signs

Signs of Aflatoxicosis

Symptoms of Aflatoxicosis

The list of medical symptoms mentioned in various sources for Aflatoxicosis may include:

Note that Aflatoxicosis symptoms usually refers to various medical symptoms known to a patient, but the phrase Aflatoxicosis signs may often refer to those signs that are only noticable by a doctor.

Signs or Symptoms of Aflatoxicosis:

Aflatoxins produce acute necrosis, cirrhosis, and carcinoma of the liver in a number of animal species; no animal species is resistant to the acute toxic effects of aflatoxins; hence it is logical to assume that humans may be similarly affected. A wide variation in LD50 values has been obtained in animal species tested with single doses of aflatoxins. For most species, the LD50 value ranges from 0.5 to 10 mg/kg body weight. Animal species respond differently in their susceptibility to the chronic and acute toxicity of aflatoxins. The toxicity can be influenced by environmental factors, exposure level, and duration of exposure, age, health, and nutritional status of diet. Aflatoxin B1 is a very potent carcinogen in many species, including nonhuman primates, birds, fish, and rodents. In each species, the liver is the primary target organ of acute injury. Metabolism plays a major role in determining the toxicity of aflatoxin B1; studies show that this aflatoxion requires metabolic activation to exert its carcinogenic effect, and these effects can be modified by induction or inhibition of the mixed function oxidase system.

The adverse effects of aflatoxins in animals (and presumably in humans) have been categorized in two general forms.

A. (Primary) Acute aflatoxicosis is produced when moderate to high levels of aflatoxins are consumed. Specific, acute episodes of disease ensue may include hemorrhage, acute liver damage, edema, alteration in digestion, absorption and/or metabolism of nutrients, and possibly death.

B. (Primary) Chronic aflatoxicosis results from ingestion of low to moderate levels of aflatoxins. The effects are usually subclinical and difficult to recognize. Some of the common symptoms are impaired food conversion and slower rates of growth with or without the production of an overt aflatoxin syndrome. (Source: FDA Bad Bug Book)

More Symptoms of Aflatoxicosis:

More detailed symptom information may be found on the symptoms of Aflatoxicosis article. In addition to the above medical information, to get a full picture of the possible signs or symptoms of this condition and also possibly the signs and symptoms of its related medical conditions, it may be necessary to examine symptoms that may be caused by:

Medical articles on signs and symptoms:

These general reference articles may be related to medical signs and symptoms of disease in general:

What are the signs of Aflatoxicosis?

The phrase "signs of Aflatoxicosis" should, strictly speaking, refer only to those signs and symptoms of Aflatoxicosis that are not readily apparent to the patient. The word "symptoms of Aflatoxicosis" is the more general meaning; see symptoms of Aflatoxicosis.

The signs and symptom information on this page attempts to provide a list of some possible signs and symptoms of Aflatoxicosis. This medical information about signs and symptoms for Aflatoxicosis has been gathered from various sources, may not be fully accurate, and may not be the full list of Aflatoxicosis signs or Aflatoxicosis symptoms. Furthermore, signs and symptoms of Aflatoxicosis may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Aflatoxicosis symptoms.


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