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Symptoms of Aflatoxicosis

Symptoms of Aflatoxicosis

The list of signs and symptoms mentioned in various sources for Aflatoxicosis includes the 11 symptoms listed below:

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Aflatoxicosis: Symptom Checkers

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Aflatoxicosis: Symptom Assessment Questionnaires

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Aflatoxicosis: Complications

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Other Possible Causes of these Symptoms

Click on any of the symptoms below to see a full list of other causes including diseases, medical conditions, toxins, drug interactions, or drug side effect causes of that symptom.

Article Excerpts About Symptoms of Aflatoxicosis:

Aflatoxins produce acute necrosis, cirrhosis, and carcinoma of the liver in a number of animal species; no animal species is resistant to the acute toxic effects of aflatoxins; hence it is logical to assume that humans may be similarly affected. A wide variation in LD50 values has been obtained in animal species tested with single doses of aflatoxins. For most species, the LD50 value ranges from 0.5 to 10 mg/kg body weight. Animal species respond differently in their susceptibility to the chronic and acute toxicity of aflatoxins. The toxicity can be influenced by environmental factors, exposure level, and duration of exposure, age, health, and nutritional status of diet. Aflatoxin B1 is a very potent carcinogen in many species, including nonhuman primates, birds, fish, and rodents. In each species, the liver is the primary target organ of acute injury. Metabolism plays a major role in determining the toxicity of aflatoxin B1; studies show that this aflatoxion requires metabolic activation to exert its carcinogenic effect, and these effects can be modified by induction or inhibition of the mixed function oxidase system.

The adverse effects of aflatoxins in animals (and presumably in humans) have been categorized in two general forms.

A. (Primary) Acute aflatoxicosis is produced when moderate to high levels of aflatoxins are consumed. Specific, acute episodes of disease ensue may include hemorrhage, acute liver damage, edema, alteration in digestion, absorption and/or metabolism of nutrients, and possibly death.

B. (Primary) Chronic aflatoxicosis results from ingestion of low to moderate levels of aflatoxins. The effects are usually subclinical and difficult to recognize. Some of the common symptoms are impaired food conversion and slower rates of growth with or without the production of an overt aflatoxin syndrome. (Source: FDA Bad Bug Book)

Aflatoxicosis as a Cause of Symptoms or Medical Conditions

When considering symptoms of Aflatoxicosis, it is also important to consider Aflatoxicosis as a possible cause of other medical conditions. The Disease Database lists the following medical conditions that Aflatoxicosis may cause:

- (Source - Diseases Database)

Medical articles and books on symptoms:

These general reference articles may be of interest in relation to medical signs and symptoms of disease in general:

About signs and symptoms of Aflatoxicosis:

The symptom information on this page attempts to provide a list of some possible signs and symptoms of Aflatoxicosis. This signs and symptoms information for Aflatoxicosis has been gathered from various sources, may not be fully accurate, and may not be the full list of Aflatoxicosis signs or Aflatoxicosis symptoms. Furthermore, signs and symptoms of Aflatoxicosis may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Aflatoxicosis symptoms.


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