What is Alpers Syndrome?

Contents

Alpers Syndrome: Introduction
Types of Alpers Syndrome
Prognosis
Complications
Prevalence
Other names for Alpers Syndrome
What causes Alpers Syndrome?
What are the symptoms of Alpers Syndrome?
Organs Affected by Alpers Syndrome
Can anyone else get Alpers Syndrome?
How is it treated?
Alpers Syndrome: Introduction

What is Alpers Syndrome?

Alpers Syndrome: A rare syndrome characterized by liver disease, seizures and progressive, episodic psychomotor retardation.

Alpers Syndrome is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Alpers Syndrome, or a subtype of Alpers Syndrome, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Alpers Syndrome: Introduction

Types of Alpers Syndrome:

Broader types of Alpers Syndrome:

How many people get Alpers Syndrome?

Prevalance of Alpers Syndrome: rare

How serious is Alpers Syndrome?

Prognosis of Alpers Syndrome: death from months to 15 years after diagnosis
Complications of Alpers Syndrome: see complications of Alpers Syndrome
Prognosis of Alpers Syndrome: The prognosis for individuals with Alpers' disease is poor. Those with the disease usually die within their first decade of life. Liver failure is usually the cause of death, although cardiorespiratory failure may also occur. (Source: excerpt from NINDS Alpers' Disease Information Page: NINDS)

What causes Alpers Syndrome?

Causes of Alpers Syndrome: see causes of Alpers Syndrome
Causes of Alpers Syndrome: While some researchers believe that Alpers' disease is caused by an underlying metabolic defect, no consistent defect has been identified. (Source: excerpt from NINDS Alpers' Disease Information Page: NINDS)

What are the symptoms of Alpers Syndrome?

Symptoms of Alpers Syndrome: see symptoms of Alpers Syndrome

Complications of Alpers Syndrome: see complications of Alpers Syndrome

Can anyone else get Alpers Syndrome?

Inheritance: see inheritance of Alpers Syndrome

Inheritance of genetic conditions: see details in inheritance of genetic diseases.

Alpers Syndrome: Testing

Diagnostic testing: see tests for Alpers Syndrome.

Misdiagnosis: see misdiagnosis and Alpers Syndrome.

How is it treated?

Doctors and Medical Specialists for Alpers Syndrome: Medical Geneticist ; see also doctors and medical specialists for Alpers Syndrome.
Treatments for Alpers Syndrome: see treatments for Alpers Syndrome
Research for Alpers Syndrome: see research for Alpers Syndrome

Organs Affected by Alpers Syndrome:

Organs and body systems related to Alpers Syndrome include:

Brain

Name and Aliases of Alpers Syndrome

Main name of condition: Alpers Syndrome

Class of Condition for Alpers Syndrome: genetic autosomal recessive

Other names or spellings for Alpers Syndrome:

Alper's Disease, Alpers' Disease, Alper Syndrome, Christensen-Krabbe syndrome, cerebral gray matter diffuse progressive degeneration-hepatic cirrhosis, gray matter, poliodystrophia cerebri, glioneural juvenalis dystrophy, Alpers progressive sclerosing poliodystrophy, Alpers-Huttenlocher syndrome, progressive neuronal degeneration of childhood with liver disease, AD, Progressive sclerosing poliodystrophy, Alpers progressive infantile poliodystrophy, Alpers diffuse degeneration of cerebral gray matter with hepatic cirrhosis, PNDC

Progressive infantile poliodystrophy Source - Diseases Database

AD, Progressive sclerosing poliodystrophy, Alpers diffuse degeneration of cerebral gray matter with hepatic cirrhosis, Alpers progressive infantile poliodystrophy, Alpers-Huttenlocher syndrome, PNDC, Progressive neuronal degeneration of childhood with liver disease
Source - Office of Rare Diseases (ORD) of the National Institutes of Health (NIH)