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Alpha thalassemia

Alpha thalassemia: Introduction

Alpha thalassemia: Thalassemia is an inherited blood disorder characterized by abnormal synthesis of hemoglobin. Hemoglobin consists of two main protein chains called alpha and beta. Alpha thalassemia involves defects in one or more of the four genes required to make each ? protein chain. The main symptom is anemia, the severity of which can vary amongst patients depending on how many defective genes are involved. More detailed information about the symptoms, causes, and treatments of Alpha thalassemia is available below.

Symptoms of Alpha thalassemia

Treatments for Alpha thalassemia

  • Mild cases may require no treatment. Regular blood transfusions are required in more severe cases. Removal (chelation) of iron buildup in body due to blood transfusion, folic acid supplements, surgical removal of spleen or allogeneic hematopoietic transplant may be helpful in some cases. Genetic counseling is recommended
  • No treatment - for mild cases
  • Folate supplementation as deficiency often occurs with high cell turnover
  • Blood transfusion
    • As necessary
  • more treatments...»

Home Diagnostic Testing

Home medical testing related to Alpha thalassemia:

Wrongly Diagnosed with Alpha thalassemia?

Alpha thalassemia: Deaths

Read more about Deaths and Alpha thalassemia.

Alpha thalassemia: Complications

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Causes of Alpha thalassemia

Read more about causes of Alpha thalassemia.

More information about causes of Alpha thalassemia:

Disease Topics Related To Alpha thalassemia

Research the causes of these diseases that are similar to, or related to, Alpha thalassemia:

Alpha thalassemia: Undiagnosed Conditions

Commonly undiagnosed diseases in related medical categories:

Misdiagnosis and Alpha thalassemia

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Alpha thalassemia: Research Doctors & Specialists

Research related physicians and medical specialists:

Other doctor, physician and specialist research services:

Evidence Based Medicine Research for Alpha thalassemia

Medical research articles related to Alpha thalassemia include:

Click here to find more evidence-based articles on the TRIP Database

Alpha thalassemia: Animations

Prognosis for Alpha thalassemia

Prognosis for Alpha thalassemia: The prognosis varies depending on how severe the condition is but even the most severe form can result in a reasonable prognosis if treatment is delivered and complications are managed appropriately.

Research about Alpha thalassemia

Visit our research pages for current research about Alpha thalassemia treatments.

Clinical Trials for Alpha thalassemia

The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.

Some of the clinical trials listed on ClinicalTrials.gov for Alpha thalassemia include:

Statistics for Alpha thalassemia

Alpha thalassemia: Broader Related Topics

User Interactive Forums

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Definitions of Alpha thalassemia:

Alpha thalassemia is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Alpha thalassemia, or a subtype of Alpha thalassemia, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Alpha thalassemia as a "rare disease".
Source - Orphanet

 

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