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Treatments for Amyloidosis

Amyloidosis: Is the Diagnosis Correct?

The first step in getting correct treatment is to get a correct diagnosis. Differential diagnosis list for Amyloidosis may include:

Hidden causes of Amyloidosis may be incorrectly diagnosed:

Amyloidosis: Research Doctors & Specialists

Research all specialists including ratings, affiliations, and sanctions.

Treatment statistics for Amyloidosis:

The following are statistics from various sources about the treatment of Amyloidosis:

  • High-dose dexamethasone had a positive response in less than 15% of amyloid patients with no cardiac involvement in the US (Amyloidosis: Recognition, Prognosis and Conventional Therapy, American Society of Hematology)
  • 4.6 years was the median survival rate for AL amyloidosis patients who were treated with melphalan and autologous stem-cell transplantation (High-dose Melphalan and Autologous Stem-Cell transplantation in Patients with AL Amyloidosis, Annals of International Medicine, 2004;140:85-93)
  • 13% mortality rate for AL amyloidosis patients 100 days after treatment with melphalan and stem-cell transplantation (High-dose Melphalan and Autologous Stem-Cell transplantation in Patients with AL Amyloidosis, Annals of International Medicine, 2004;140:85-93)
  • 28% of AL amyloidosis patients showed a response to treatment with oral melphalan and prednisone in the US (Blood first Edition Paper, 2003;DOI 10.1182)
  • 30% of AL amyloidosis patients who showed a response to treatment with oral melphalan and prednisone took a year to respond in the US (Blood first Edition Paper, 2003;DOI 10.1182)

Hospital statistics for Amyloidosis:

These medical statistics relate to hospitals, hospitalization and Amyloidosis:

  • 0.008% (995) of hospital consultant episodes were for amyloidosis in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 86% of hospital consultant episodes for amyloidosis required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 57% of hospital consultant episodes for amyloidosis were for men in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 43% of hospital consultant episodes for amyloidosis were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 23% of hospital consultant episodes for amyloidosis required emergency hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • more hospital information...»

Discussion of treatments for Amyloidosis:

No effective treatment has been found to reverse the effects of amyloidosis. Combination drug therapy with melphalan (a cancer drug) and prednisone (an anti-inflammatory steroid drug) may improve organ function and survival rates by interrupting the growth of cells that produce amyloid protein. These are the same drugs used in chemotherapy to treat certain cancers, and they may have serious side effects, such as nausea and vomiting, hair loss, and fatigue. (Source: excerpt from Amyloidosis and Kidney Disease: NIDDK)

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