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Treatments for Ankylosing spondylarthritis

Treatment List for Ankylosing spondylarthritis

The list of treatments mentioned in various sources for Ankylosing spondylarthritis includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.

  • Treatment of ankylosing spondylitis depends on the severity and duration of the symptoms, and extra-articular manifestations. No drug treatment has been proven to modify the course of the disease, although the newer TNF blockers may have potential to do this. Treatments include:
    • Explanation - Education plays an important role in arthritis management
    • Rest - during bouts of active inflammation
    • Exercise - graduated exercise program recommended to maintain good joint function
    • Physiotherapy - can assist with regaining and maintaining joint function
    • Occupational therapy - can assist with management at home and mobility aids
    • Simple analgesics (used regularly) - such as paracetamol can be effective in control of pain either alone or in combination with other agents
    • NSAIDs - mainstay of therapy and should be used regularly to achieve a good anti-inflammatory effect. Problems may arise with gastrointestinal and cardiovascular side effects
    • Corticosteroids orally or intra-articular - may be used when response to NSAIDs is insufficient. Should be used for short term management only
    • Disease Modifying Antirheumatic Drugs (DMARDS) - include methotrexate and sulfasalazine, and are used when symptoms are not controlled with NSAIDS alone
    • TNF (Tumour necrosis factor) blockers - Entanercept, Infliximab, Adalimumab, shown to be effective in treatment of ankylosing spondylitis, and used when NSAID therapy has failed
    • Surgery to correct spinal deformities and joint replacements may be indicated

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