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Glossary for Ankylosing Spondylitis

  • Adolescent conditions: Symptoms that are evident due to puberty
  • Alkaptonuria: A rare disorder where the abnormal accumulation of a particular acid (homogentisic acid) in the body causes connective tissue and bone damage. This damage gives tissues a dark or bluish discoloration.
  • Angelman syndrome: A rare genetic disorder characterized by a puppet-like gait, fits of laughter and characteristic facial features.
  • Ankylosing Spondylitis: Inflammation of spinal joints similar to rheumatoid arthritis.
  • Aortic Aneurysm, Thoracic: Bulging and weakness of the aorta in the area of the chest. The condition is life-threatening as death can occur rapidly if the aneurysm bursts.
  • Aortic valve incompetence: A condition characterized by an inability of the aortic valve to function effectively
  • Arthritis: General name for any type of joint inflammation, but often means age-related osteoarthritis.
  • Autoimmune diseases: A group of disorders in which the primary cause is the an inflammatory reaction caused by the body's own immune system attacking tissues
  • Back conditions: A group of conditions that affect the back
  • Cauda equina syndrome: Is a neurological syndrome which occurs when a vertebral disc protrudes and compresses the spinal cord.
  • Cerebral Autosomal Recessive Arteriopathy with Subcortical Infarcts and Leukoencephalopathy: A rare inherited condition characterized primarily by progressive degeneration of the brain white matter and disease of the brain blood vessels as well as additional symptoms not involving the brain e.g. thin skin, alopecia and spinal disc disease.
  • Chest pain: Pain in the chest area.
  • Disc Disorders: Disorders that affect the discs of the spine
  • Enthesopathy: A disease process occurring at locations where tendons and ligaments attach to bone.
  • Fatigue: Excessive tiredness or weakness.
  • Fever: Elevation of the body temperature above the normal 37 degrees celsius
  • Hyperparathyroidism: Increased secretion of parathyroid hormone from the parathyroid glands.
  • Immune disorders: Disorders that affect the immune system
  • Inflammatory bowel disease: Inflammatory bowel disease refers to digestive symptoms resulting from chronic bowel inflammation. Crohn's disease and ulcerative colitis are two of the main subtypes of the disease. Scientists have discovered an array of genetic mutations which can result in an increased susceptibility to inflammatory bowel disease. Not all people with the genetic anomaly will develop the condition but it can increase the risk especially if other environmental factors are also present. The severity of the disease that develops is variable.
  • Juvenile Rheumatoid Arthritis: Chronic arthritis affecting children and teens
  • Lower back pain: Pain in the lower back region
  • Marfan syndrome: A genetic connective tissue disorder involving a defect of chromosome 15q21.1 which affects the production of the fibrillin needed to make connective tissue.
  • Musculoskeletal conditions: Medical conditions affecting the musculoskeletal system of bones, muscles and related structures.
  • Non-pathogenic inflammatory conditions: Medical disorders that cause inflammation, but are not due to any infectious pathogen.
  • Osteoarthritis: Osteoarthritis is a chronic condition characterised by mechanical disrturbances due to degradation of joints. It is the most common form of arthritis, and the leading cause of chronic disability.
  • Osteoporosis: Bone thinning and weakening from bone calcium depletion.
  • Pain conditions: Diseases characterized by pain and pain-like symptoms.
  • Psoriatic Arthritis: Psoriatic arthritis is a chronic disease characterized by inflammation of the skin (psoriasis) and joints (arthritis). Psoriatic arthritis is said to be a seronegative spondyloarthropathy and therefore occurs more commonly in patients with tissue type HLA-B27.
  • Reactive arthritis: The inflammation of a joint
  • Reiterís syndrome: A form of reactive arthritis characterized by arthritis, urethritis, conjunctivitis and skin lesions.
  • Rheumatic conditions: Any condition that affects ones joints
  • Rheumatoid arthritis: Autoimmune form of arthritis usually in teens or young adults.
  • Sciatica: Sciatica is a set of symptoms including pain that may be caused by general compression and/or irritation of one of five nerve roots that give rise to the sciatic nerve, or by compression or irritation of the sciatic nerve itself.
  • Seronegative Arthritis: Classification given to the group of joint conditions with similar features to rheumatoid arthritis, but affecting different joints and lacking the specific autoantibodies used to identify rheumatoid arthritis
  • Seronegative spondyloarthropathy: Spondyloarthropathy that is negative to rheumatoid facotr
  • Spinal conditions: Any condition that affects the spine
  • Spinal stenosis: Narrowing of the spinal cavity around the spinal cord.
  • Spine symptoms: Symptoms affecting the spine
  • Spondylitis: Inflammation of one or multiple bony vertebrae of the spine
  • Stiff back: Reduced mobility or movement of the back
  • Ulcerative colitis: Ulcerative colitis (Colitis ulcerosa, UC) is a form of inflammatory bowel disease (IBD). Ulcerative colitis is a form of colitis, a disease of the intestine, specifically the large intestine or colon, that includes characteristic ulcers, or open sores, in the colon.
  • Uveitis: A condition which is characterised by the inflammation of the uvea of the eye

 

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