Clinical Trials for Ascites
Clinical trials are research studies conducted in an effort to improve overall patient health and care.
Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition.
Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks.
A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.
A brief description of each phase:
- Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
- Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
- Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
- Phase IV: These studies monitor long-term side effects after the treatment has been marketed.
Clinical Trials data for Ascites is grouped into the following categories:-
The format for each of the following is:
- The name of the trial,
- followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
- followed by a list of drug/s, if any, used in the trial
ClinicalTrials.gov has listed the following trials for Ascites:
- Safety and Efficacy Study of the Trifunctional Antibody Catumaxomab to Treat Recurrent Symptomatic Malignant Ascites - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - catumaxomab
- Vasoconstrictors as Alternatives to Albumin After LVP (Large-Volume Paracentesis) in Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006) - octreotide plus midodrine,albumin
- Prevention of Decompensation in Liver Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006) - losartan (drug)
- Study of the Effect of Intravenous AVE0005 (VEGF Trap) in Advanced Ovarian Cancer Patients With Recurrent Symptomatic Malignant Ascites - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - AVE0005 (VEGF Trap)
- Cirrhotic Ascites Treatment With Satavaptan in Patients With Ascites Due to Cirrhosis of the Liver (CATS) - This study is currently recruiting patients (Current: 23 Nov 2006) - satavaptan
- North American Study for the Treatment of Refractory Ascites (NASTRA) - This study has been completed (Current: 23 Nov 2006)
- Renal and Cardiovascular Effects of Terlipressin in Patients With Cirrhosis and Ascites - This study has been completed (Current: 23 Nov 2006) - Terlipressin
- Satavaptan in the Prevention of Ascites Recurrence With in Patients With Ascites Due to Cirrhosis of the Liver (SPARe-1) - This study is currently recruiting patients (Current: 23 Nov 2006) - Satavaptan
- Satavaptan for the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Liver (SPARe-2) - This study is currently recruiting patients (Current: 23 Nov 2006) - Satavaptan
- SCH-58500 in Treating Patients With Primary Ovarian, Fallopian Tube, or Peritoneal Cancer - This study has been completed (Current: 23 Nov 2006) - SCH-58500
- ILX-295501 in Treating Patients With Stage III or Stage IV Ovarian Cancer That Has Not Responded to Previous Treatment - This study is no longer recruiting patients (Current: 23 Nov 2006) - ILX-295501
- The Use of Drugs to Improve Kidney Function in Patients With Liver and Kidney Dysfunction - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Midodrine, albumin, octreotide LAR
- Mitomycin as a Hyperthermic Peritoneal Perfusion in Treating Patients With Malignant Ascites - This study is currently recruiting patients (Current: 23 Nov 2006) - mitomycin
- Adefovir Dipivoxil to Treat Hepatitis B in HIV-Infected Patients - This study has been completed (Current: 23 Nov 2006) - Adefovir
- Noradrenalin vs Terlipressin in Hepatorenal Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Noradrenalin or terlipressin
- End Stage Liver Disease and Body Composition Assessment: Utilizing Bioelectric Impedance Analysis (BIA) - This study is currently recruiting patients (Current: 23 Nov 2006)
- Ecteinascidin 743 in Treating Adults With Advanced Solid Tumors - This study is no longer recruiting patients (Current: 23 Nov 2006) - ecteinascidin 743
- Penclomedine in Treating Patients With Solid Tumors or Lymphoma - This study has been completed (Current: 23 Nov 2006) - penclomedine
- Decitabine in Treating Patients With Melanoma or Other Advanced Cancer - This study has been completed (Current: 23 Nov 2006) - decitabine
- Combination Chemotherapy in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006) - fluorouracil,leucovorin calcium,topotecan
- L-778,123 in Treating Patients With Recurrent or Refractory Solid Tumors - This study is no longer recruiting patients (Current: 23 Nov 2006) - L-778,123
- Interleukin-12 Followed by Interferon Alfa in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006) - interferon alfa,interleukin-12
- Combination Chemotherapy in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006) - fluorouracil,leucovorin calcium,SCH 66336
- Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006) - amifostine,carboplatin,cyclophosphamide,sargramostim
- Paclitaxel Plus L-778,123 in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphomas - This study is no longer recruiting patients (Current: 23 Nov 2006) - L-778,123,L-778,123/paclitaxel,paclitaxel
- Oxaliplatin With Or Without Floxuridine and Leucovorin in Treating Patients With Metastatic Cancer of the Peritoneum - This study has been completed (Current: 23 Nov 2006) - floxuridine,leucovorin calcium,oxaliplatin
- Treatment With Octreotide in Patients With Lymphangioleiomyomatosis - This study is currently recruiting patients (Current: 23 Nov 2006) - Octreotide
- EF5 in Detecting Oxygen Level and Blood Vessels in Tumor Cells of Patients Undergoing Photodynamic Therapy for Intraperitoneal or Pleural Cancer - This study is currently recruiting patients (Current: 23 Nov 2006) - EF5
- Octreotide in Treating Patients With Cancer-Related Malignant Ascites - This study is currently recruiting patients (Current: 23 Nov 2006) - octreotide acetate
- TIPS With Coated Stents for Refractory Ascites in Patients With Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006)
- AVE0005 (VEGF Trap) in Patients With Recurrent Symptomatic Malignant Ascites - This study is currently recruiting patients (Current: 23 Nov 2006) - AVE0005 (VEGF Trap)
The format for each of the following is:
- The drug,
- followed by the name of the trial,
- followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
ClinicalTrials.gov has listed the following drugs in trials for Ascites:
- AVE0005 (VEGF Trap) - AVE0005 (VEGF Trap) in Patients With Recurrent Symptomatic Malignant Ascites - This study is currently recruiting patients (Current: 23 Nov 2006)
- AVE0005 (VEGF Trap) - Study of the Effect of Intravenous AVE0005 (VEGF Trap) in Advanced Ovarian Cancer Patients With Recurrent Symptomatic Malignant Ascites - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
- Adefovir - Adefovir Dipivoxil to Treat Hepatitis B in HIV-Infected Patients - This study has been completed (Current: 23 Nov 2006)
- Albumin - Vasoconstrictors as Alternatives to Albumin After LVP (Large-Volume Paracentesis) in Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Amifostine - Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Carboplatin - Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Catumaxomab - Safety and Efficacy Study of the Trifunctional Antibody Catumaxomab to Treat Recurrent Symptomatic Malignant Ascites - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
- Cyclophosphamide - Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Decitabine - Decitabine in Treating Patients With Melanoma or Other Advanced Cancer - This study has been completed (Current: 23 Nov 2006)
- EF5 - EF5 in Detecting Oxygen Level and Blood Vessels in Tumor Cells of Patients Undergoing Photodynamic Therapy for Intraperitoneal or Pleural Cancer - This study is currently recruiting patients (Current: 23 Nov 2006)
- Ecteinascidin 743 - Ecteinascidin 743 in Treating Adults With Advanced Solid Tumors - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Floxuridine - Oxaliplatin With Or Without Floxuridine and Leucovorin in Treating Patients With Metastatic Cancer of the Peritoneum - This study has been completed (Current: 23 Nov 2006)
- Fluorouracil - Combination Chemotherapy in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Fluorouracil - Combination Chemotherapy in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006)
- ILX-295501 - ILX-295501 in Treating Patients With Stage III or Stage IV Ovarian Cancer That Has Not Responded to Previous Treatment - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Interferon Alfa - Interleukin-12 Followed by Interferon Alfa in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Interleukin-12 - Interleukin-12 Followed by Interferon Alfa in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006)
- L-778,123/paclitaxel - Paclitaxel Plus L-778,123 in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphomas - This study is no longer recruiting patients (Current: 23 Nov 2006)
- L-778,123 - L-778,123 in Treating Patients With Recurrent or Refractory Solid Tumors - This study is no longer recruiting patients (Current: 23 Nov 2006)
- L-778,123 - Paclitaxel Plus L-778,123 in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphomas - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Leucovorin Calcium - Combination Chemotherapy in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Leucovorin Calcium - Combination Chemotherapy in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Leucovorin Calcium - Oxaliplatin With Or Without Floxuridine and Leucovorin in Treating Patients With Metastatic Cancer of the Peritoneum - This study has been completed (Current: 23 Nov 2006)
- Losartan (Drug) - Prevention of Decompensation in Liver Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Midodrine, albumin, octreotide LAR - The Use of Drugs to Improve Kidney Function in Patients With Liver and Kidney Dysfunction - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
- Mitomycin - Mitomycin as a Hyperthermic Peritoneal Perfusion in Treating Patients With Malignant Ascites - This study is currently recruiting patients (Current: 23 Nov 2006)
- Noradrenalin or terlipressin - Noradrenalin vs Terlipressin in Hepatorenal Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
- Octreotide Acetate - Octreotide in Treating Patients With Cancer-Related Malignant Ascites - This study is currently recruiting patients (Current: 23 Nov 2006)
- Octreotide Plus Midodrine - Vasoconstrictors as Alternatives to Albumin After LVP (Large-Volume Paracentesis) in Cirrhosis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Octreotide - Treatment With Octreotide in Patients With Lymphangioleiomyomatosis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Oxaliplatin - Oxaliplatin With Or Without Floxuridine and Leucovorin in Treating Patients With Metastatic Cancer of the Peritoneum - This study has been completed (Current: 23 Nov 2006)
- Paclitaxel - Paclitaxel Plus L-778,123 in Treating Patients With Recurrent or Refractory Solid Tumors or Lymphomas - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Penclomedine - Penclomedine in Treating Patients With Solid Tumors or Lymphoma - This study has been completed (Current: 23 Nov 2006)
- SCH 66336 - Combination Chemotherapy in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006)
- SCH-58500 - SCH-58500 in Treating Patients With Primary Ovarian, Fallopian Tube, or Peritoneal Cancer - This study has been completed (Current: 23 Nov 2006)
- Sargramostim - Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Satavaptan - Cirrhotic Ascites Treatment With Satavaptan in Patients With Ascites Due to Cirrhosis of the Liver (CATS) - This study is currently recruiting patients (Current: 23 Nov 2006)
- Satavaptan - Satavaptan for the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Liver (SPARe-2) - This study is currently recruiting patients (Current: 23 Nov 2006)
- Satavaptan - Satavaptan in the Prevention of Ascites Recurrence With in Patients With Ascites Due to Cirrhosis of the Liver (SPARe-1) - This study is currently recruiting patients (Current: 23 Nov 2006)
- Terlipressin - Renal and Cardiovascular Effects of Terlipressin in Patients With Cirrhosis and Ascites - This study has been completed (Current: 23 Nov 2006)
- Topotecan - Combination Chemotherapy in Treating Patients With Advanced Cancer - This study is no longer recruiting patients (Current: 23 Nov 2006)
The trial data on this page has been sourced from
