Autoimmune Lymphoproliferative Syndrome: ALPS is a rare disease that affects both children and adults. ALPS stands for Autoimmune LymphoProliferative (lim-fo ... more about Autoimmune Lymphoproliferative Syndrome.
Autoimmune Lymphoproliferative Syndrome: An inherited autoimmune condition characterized by proliferation of lymphocytes and autoimmunity against the body's own blood cells resulting in premature death of certain blood cells. More detailed information about the symptoms, causes, and treatments of Autoimmune Lymphoproliferative Syndrome is available below.
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ALPS is a rare disease that affects both children and adults. ALPS stands for Autoimmune LymphoProliferative (lim-fo-pro-lif'-er-a-tive) Syndrome. Each of these three words helps describe the main features of this condition. The word autoimmune (self-immune) identifies ALPS as a disease of the immune system. The tools used to fight germs turn against our own cells and cause problems. The word lymphoproliferative describes the unusually large numbers of white blood cells (called lymphocytes (lim'-fo-sites)) stored in the lymph nodes and spleens of people with ALPS. The word syndrome refers to the many common symptoms shared by ALPS patients. (Source: excerpt from Autoimmune Lymphoproliferative Syndrome (ALPS): NIAID)
Autoimmune Lymphoproliferative Syndrome is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Autoimmune Lymphoproliferative Syndrome, or a subtype of Autoimmune Lymphoproliferative Syndrome,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
Ophanet, a consortium of European partners,
currently defines a condition rare when it affects 1 person per 2,000.
They list Autoimmune Lymphoproliferative Syndrome as a "rare disease".
Source - Orphanet
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