Christmas disease: Haemophilia B. An x-linked recessive form of haemophilia due to deficiency of coagulation factor IX. More detailed information about the symptoms, causes, and treatments of Christmas disease is available below.
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A deficiency of blood coagulation factor IX inherited as an X-linked disorder. (Also known as Christmas Disease, after the first patient studied in detail, not the holy day.) Historical and clinical features resemble those in classic hemophilia (HEMOPHILIA A), but patients present with fewer symptoms. Severity of bleeding is usually similar in members of a single family. Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma. Treatment is similar to that for hemophilia A. (From Cecil Textbook of Medicine, 19th ed, p1008) - (Source - Diseases Database)
Christmas disease is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Christmas disease, or a subtype of Christmas disease,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
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