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Chromosome 15 inverted duplication: A rare chromosomal disorder involving an duplicated section of chromosome 15 which is reversed end-to-end resulting in various abnormalities. More detailed information about the symptoms, causes, and treatments of Chromosome 15 inverted duplication is available below.
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Inverted duplication of chromosome 15, wherein a segment of chromosome 15 is reversed end-to-end, associated with variable clinical and cytogenetic manifestations. Supernumerary inv dup(15) chromosomes are most commonly associated with moderate to severe mental retardation, behavioral disorders, and seizures with a wide variety of structural malformation or with the normal phenotype. Inv dup(15) was reported in Angelman and Prader-Willi syndromes. - (Source - Diseases Database)
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