Chronic granulomatous disease is caused by inherited genetic defects.
Gender of Patients for Chronic Granulomatous Disease: Males 4 times more likely than females....more »
Gender Ratio of Chronic Granulomatous Disease: male predominance...more »
Gender Profile of Chronic Granulomatous Disease: Males are four times more likely to get this disease than females. (Source: excerpt from Primary Immune Deficiency, NIAID Fact Sheet: NIAID) ...more »
To research the causes of Chronic Granulomatous Disease, consider researching the causes of these these diseases that may be similar, or associated with Chronic Granulomatous Disease:
Causes of Types of Chronic Granulomatous Disease: Review the cause informationfor the various types of Chronic Granulomatous Disease:
Causes of Broader Categories of Chronic Granulomatous Disease: Review the causal information about the various more general categories of medical conditions:
Causes: Chronic Granulomatous Disease:
Patients with CGD have poorly-functioning
phagocytes caused by mutations in one of four different genes. The
abnormal genes cannot make proteins required for the production of
oxygen byproducts, such as hydrogen peroxide and superoxide, which
kill bacteria and fungi. (Source: excerpt from Primary Immune Deficiency, NIAID Fact Sheet: NIAID)
As with all medical conditions, there may be many causal factors. Further relevant information on causes of Chronic Granulomatous Disease may be found in:
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