Diseases » Chronic Granulomatous Disease » Introduction

Chronic Granulomatous Disease

Chronic Granulomatous Disease: Introduction

Chronic Granulomatous Disease: The CGD patient's defense system is not effective against certain bacteria and fungi, including E. coli and Staphylococcus aureus, as well ... more about Chronic Granulomatous Disease.

Chronic Granulomatous Disease: A very rare inherited blood disorder where certain cells involved with immunity (phagocytes) are unable to destroy bacteria and hence the patient suffers repeated bacterial infections. More detailed information about the symptoms, causes, and treatments of Chronic Granulomatous Disease is available below.

Symptoms of Chronic Granulomatous Disease

• Fevers
• Skin rashes
• Persistent cough
• Boils
• Gum disease
• more symptoms...»

See full list of 28 symptoms of Chronic Granulomatous Disease

Treatments for Chronic Granulomatous Disease

• Antibiotics - for infections; usually high-doses
• Preventive oral antibiotics
• Trimethoprim/sulfamethoxazole combination
• Surgical abscess drainage
• Steroids - for gastrointestinal or urinary obstructions.
• more treatments...»

See full list of 8 treatments for Chronic Granulomatous Disease

Wrongly Diagnosed with Chronic Granulomatous Disease?

• Misdiagnosis of Chronic Granulomatous Disease
• Failure to diagnose Chronic Granulomatous Disease
• Undiagnosed: Chronic Granulomatous Disease

Chronic Granulomatous Disease: Deaths

Read more about Deaths and Chronic Granulomatous Disease.

Types of Chronic Granulomatous Disease

• Autosomal recessive CGD
• X-linked CGD
• more types...»

Read more about Types of Chronic Granulomatous Disease

Diagnostic Tests for Chronic Granulomatous Disease

• CBC
• Immune function blood tests
• Immunoglobulins level - usually elevated.
• Chest x-rays - these may show granulomas
• Erythrocyte sedimentation rate (ESR)
• more tests...»

See full list of 6 diagnostic tests for Chronic Granulomatous Disease

Chronic Granulomatous Disease: Complications

Review possible medical complications related to Chronic Granulomatous Disease:

• Anemia
• Gastrointestinal blockage (see Digestive symptoms)
• Urinary blockage (see Lack of urine)
• more complications...»

Causes of Chronic Granulomatous Disease

Read more about causes of Chronic Granulomatous Disease.

Disease Topics Related To Chronic Granulomatous Disease

Research the causes of these diseases that are similar to, or related to, Chronic Granulomatous Disease:

• Progressive septic granulomatosis
• CGD
• X-linked CGD
• X-CGD
• X91 CGD
• more related diseases...»

Evidence Based Medicine Research for Chronic Granulomatous Disease

Medical research articles related to Chronic Granulomatous Disease include:

• Management of cervical cancer
• Treatment of Aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America.
• 1) General recommendations on immunization: recommendations of the Advisory Committee on Immunization Practices (ACIP). 2) Update: recommendations from the Advisory Committee on Immunization Practices (ACIP) regarding administration of combination MMRV va
• Guidelines on male infertility
• Glucose-6-phosphate dehydrogenase deficiency
• Aspergillosis (Treatment)
• more research...»

Click here to find more evidence-based articles on the TRIP Database

Research about Chronic Granulomatous Disease

Visit our research pages for current research about Chronic Granulomatous Disease treatments.

Clinical Trials for Chronic Granulomatous Disease

The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.

Some of the clinical trials listed on ClinicalTrials.gov for Chronic Granulomatous Disease include:

• Treatment of Chronic Granulomatous Disease With Allogeneic Stem Cell Transplantation Versus Standard of Care - This study has been completed (Current: 23 Nov 2006) - T-Cell Depleted & CD34+Select/w/StemCell Enriched Product
• A Phase IV Study of Recombinant Human Gamma Interferon in Patients With Chronic Granulomatous Diseases of Childhood - This study has been completed (Current: 23 Nov 2006)
• Use of G-CSF to Obtain Blood Cell Precursors - This study is currently recruiting patients (Current: 23 Nov 2006)
• Gene Therapy for Chronic Granulomatous Diseases - Long-Term Follow-up - This study is no longer recruiting patients (Current: 23 Nov 2006) - Gene Therapy Method for CGD
• Stem Cell Transplant Following Low-Intensity Chemotherapy to Treat Chronic Granulomatous Disease - This study has been completed (Current: 23 Nov 2006)
• more trials...»

See full list of 17 Clinical Trials for Chronic Granulomatous Disease

Statistics for Chronic Granulomatous Disease

• Medical statistics for Chronic Granulomatous Disease
• Prevalence and incidence statistics for Chronic Granulomatous Disease
• Death and Mortality statistics for Chronic Granulomatous Disease
• Society statistics for Chronic Granulomatous Disease

Chronic Granulomatous Disease: Broader Related Topics

• Primary Immune Deficiency
• Immune deficiency conditions
• Genetic Disease
• more types...»

Types of Chronic Granulomatous Disease

Chronic Granulomatous Disease Message Boards

Related forums and medical stories:

• Immune Conditions (56)
  • IGA Deficiency
  • hypogammaglobulinemia-2nd opinions
  • Cvid
  • Never ending cough
  • Diarrhea and gas problems possibly related with my IgA deficiency?
  • More user stories

User Interactive Forums

Read about other experiences, ask a question about Chronic Granulomatous Disease, or answer someone else's question, on our message boards:

• I can not get a diagnosis. Please help.
• Tell us your medical story.
• Share your misdiagnosis story.
• What is the best treatment for this?
• See all the forums.

Article Excerpts about Chronic Granulomatous Disease

The CGD patient's defense system is not effective against certain bacteria and fungi, including E. coli and Staphylococcus aureus, as well as less common germs like Pseudomonas, Serratia, and Aspergillus. (Source: excerpt from Primary Immune Deficiency, NIAID Fact Sheet: NIAID)

Definitions of Chronic Granulomatous Disease:

A recessive X-linked defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. - (Source - Diseases Database)

Chronic Granulomatous Disease is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Chronic Granulomatous Disease, or a subtype of Chronic Granulomatous Disease, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Chronic Granulomatous Disease as a "rare disease".
Source - Orphanet

 » Next page: What is Chronic Granulomatous Disease?

Medical Tools & Articles:

Tools & Services:

• Bookmark this page
• Symptom Search
• Symptom Checker
• Medical Dictionary

Medical Articles:

• Disease & Treatments Search
• Misdiagnosis Center
• Full list of interesting articles

Forums & Message Boards

• Ask or answer a question at the Boards:
• I cannot get a diagnosis. Please help.
• Tell us your medical story.
• Share your misdiagnosis story.
• What is the best treatment for my condition?
• See all the Boards.

   

homepage | back to top

Search Specialists by State and City

Choose... GENERAL PRACTICE CARDIAC HEALTH WOMEN'S HEALTH CANCER CARE RADIOLOGY MENTAL HEALTH PATHOLOGY EAR, NOSE, THROAT MEDICINE GENETICS NEUROLOGY DIALYSIS CARE SURGERY ORTHOPEDICS/SPORTS MEDICINE CHILDREN'S HEALTH OTHER SPECIALTIES