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Chronic Inflammatory Demyelinating Polyneuropathy

Chronic Inflammatory Demyelinating Polyneuropathy: Introduction

Chronic inflammatory demyelinating polyneuropathy is an ongoing, long-term neurological disorder in which the peripheral nerves become inflamed and damaged. Chronic inflammatory demyelinating polyneuropathy is a rare disorder that is treatable, but in some cases can result in permanent numbness or weakness of the arms or legs. Chronic inflammatory demyelinating polyneuropathy is also known as CIPD and chronic inflammatory polyneuropathy. Chronic inflammatory demyelinating polyneuropathy is considered a long-term counterpart of Guillain-Barre syndrome.

It is believed the chronic inflammatory demyelinating polyneuropathy may be caused by an autoimmune reaction in which the body's immune system mistakes the myelin sheath of the peripheral nerves as a dangerous substance and attacks it. The myelin sheath is the fatty covering that covers and protects the nerves.

Chronic inflammatory demyelinating polyneuropathy generally develops slowly over a period of months. Symptoms of chronic inflammatory demyelinating polyneuropathy include a sensation of pain, numbness, tingling, or prickling that begins in the toes or fingers. Chronic inflammatory demyelinating polyneuropathy also leads to weakness of the legs and arms and difficulty walking. For more details about symptoms and complications, see symptoms of chronic inflammatory demyelinating polyneuropathy.

Diagnosing chronic inflammatory demyelinating polyneuropathy and its root cause begins with taking a thorough personal and family medical history, including symptoms, and completing a physical examination, including a neurological examination. A neurological exam evaluates the nerves and nervous system and such functions as reflexes, sensation, movement, balance, coordination, vision, and hearing. Chronic inflammatory demyelinating polyneuropathy is generally diagnosed by a specialist in neurological diseases and disorders called a neurologist.

Diagnostic tests may include an electromyography (EMG) which tests the nerve and electrical activity of muscles. A nerve conduction test may also be performed to test how fast the nerves transmit impulses.

A test called a lumbar puncture or spinal tap may also be done. In this test a small amount of cerebral spinal fluid is removed from the spine with a small needle and tested for the presence of protein. Other tests may include blood tests and an urinanalysis.

A diagnosis of chronic inflammatory demyelinating polyneuropathy and its cause can easily be delayed or missed because symptoms develop gradually. Symptoms can also be similar to symptoms of other disorders and diseases. For information about disease and disorders that can mimic chronic inflammatory demyelinating polyneuropathy, refer to misdiagnosis of chronic inflammatory demyelinating polyneuropathy.

Treatment of chronic inflammatory demyelinating polyneuropathy may include medication, specialized procedures, and physical therapy. For more information on treatment, refer to treatment of chronic inflammatory demyelinating polyneuropathy. ...more »

Chronic Inflammatory Demyelinating Polyneuropathy: Chronic inflammatory demyelinating polyneuropathy (CIDP) is a neurological disorder characterized by slowly progressive weakness and sensory ... more about Chronic Inflammatory Demyelinating Polyneuropathy.

Chronic Inflammatory Demyelinating Polyneuropathy: A rare disorder involving swelling of nerve roots and destruction of the protective layer around nerves. Severe symptoms can take up to a year or more to develop. More detailed information about the symptoms, causes, and treatments of Chronic Inflammatory Demyelinating Polyneuropathy is available below.

Chronic Inflammatory Demyelinating Polyneuropathy: Symptoms

Symptoms of chronic inflammatory demyelinating polyneuropathy can occur in both sexes and affects men more women. Chronic inflammatory demyelinating polyneuropathy can occur at any age but is most common in young adults.

People with chronic inflammatory demyelinating polyneuropathy can experience a variety of symptoms, commonly abnormal or unusual sensations and weakness of the ...more symptoms »

Chronic Inflammatory Demyelinating Polyneuropathy: Treatments

Treatment plans for chronic inflammatory demyelinating polyneuropathy are individualized depending on the severity, the presence of coexisting diseases, the age of the patient, and other factors. The goals of treatment are to relieve the discomfort, maximize a person's ability to walk and function normally and minimize the risk of developing permanent nerve damage and ...more treatments »

Chronic Inflammatory Demyelinating Polyneuropathy: Misdiagnosis

A diagnosis of chronic inflammatory demyelinating polyneuropathy and its cause may be delayed or missed because the disorder generally develops very gradually, and people with the condition may be unaware of it initially. In addition, symptoms of chronic inflammatory demyelinating polyneuropathy are similar to symptoms of other diseases and disorders. These include diabetic ...more misdiagnosis »

Symptoms of Chronic Inflammatory Demyelinating Polyneuropathy

Treatments for Chronic Inflammatory Demyelinating Polyneuropathy

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Wrongly Diagnosed with Chronic Inflammatory Demyelinating Polyneuropathy?

Chronic Inflammatory Demyelinating Polyneuropathy: Related Patient Stories

Chronic Inflammatory Demyelinating Polyneuropathy: Complications

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Causes of Chronic Inflammatory Demyelinating Polyneuropathy

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Disease Topics Related To Chronic Inflammatory Demyelinating Polyneuropathy

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Chronic Inflammatory Demyelinating Polyneuropathy: Undiagnosed Conditions

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Chronic Inflammatory Demyelinating Polyneuropathy: Research Doctors & Specialists

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Hospitals & Clinics: Chronic Inflammatory Demyelinating Polyneuropathy

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Chronic Inflammatory Demyelinating Polyneuropathy: Rare Types

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Evidence Based Medicine Research for Chronic Inflammatory Demyelinating Polyneuropathy

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Chronic Inflammatory Demyelinating Polyneuropathy: Animations

Prognosis for Chronic Inflammatory Demyelinating Polyneuropathy

Prognosis for Chronic Inflammatory Demyelinating Polyneuropathy: The course of CIDP varies widely among individuals. Some may have a bout of CIDP followed by spontaneous recovery, while others may have many bouts with partial recovery in between relapses. The disease is a treatable cause of acquired neuropathy and initiation of early treatment to prevent loss of nerve cells is recommended. However, some individuals are left with some residual numbness or weakness. (Source: excerpt from NINDS Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Information Page: NINDS)

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Chronic Inflammatory Demyelinating Polyneuropathy: Broader Related Topics

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Article Excerpts about Chronic Inflammatory Demyelinating Polyneuropathy

Chronic inflammatory demyelinating polyneuropathy (CIDP) is a neurological disorder characterized by slowly progressive weakness and sensory dysfunction of the legs and arms. The disorder, which is sometimes called chronic relapsing polyneuropathy, is caused by damage to the myelin sheath of the peripheral nerves. The myelin sheath is the fatty covering—which acts as an insulator—on fibers in the nerves. (Source: excerpt from NINDS Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) Information Page: NINDS)

Definitions of Chronic Inflammatory Demyelinating Polyneuropathy:

A slowly progressive autoimmune demyelinating disease of peripheral nerves and nerve roots. Clinical manifestations include weakness and sensory loss in the extremities and enlargement of peripheral nerves. The course may be relapsing-remitting or demonstrate a step-wise progression. Protein is usually elevated in the spinal fluid and cranial nerves are typically spared. GUILLAIN-BARRE SYNDROME features a relatively rapid progression of disease which distinguishes it from this condition. (Adams et al., Principles of Neurology, 6th ed, p1337) - (Source - Diseases Database)

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Chronic Inflammatory Demyelinating Polyneuropathy as a "rare disease".
Source - Orphanet

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