Symptoms of Creutzfeldt-Jakob Disease
Symptoms of Creutzfeldt-Jakob Disease: Introduction
The symptoms of Creutzfeldt-Jakob disease advance rapidly compared to many other neurodegenerative diseases, such as Alzheimer's disease and Huntington's disease. Symptoms affect behavior, emotion, motor skills, and cognitive functioning. The hallmark of Creutzfeldt-Jakob disease is quickly progressing dementia.
Symptoms of dementia and other symptoms generally start at about age 60. The way that symptoms of Creutzfeldt-Jakob disease develop varies between individuals. However, every person with Creutzfeldt-Jakob disease ultimately becomes permanently and completely disabled.
Early symptoms include memory problems, behavioral changes, personality changes, failing vision, and problems with thinking and judgement. Symptoms progress quickly, and the person's condition seriously deteriorates.
Later symptoms include worsening of early symptoms and the development of involuntary muscle jerking. Blindness can occur and the ability to speak is lost. Eventually, people with Creutzfeldt-Jakob disease fall into a coma. Death usually occurs within about a year after the onset of symptoms due to such complications as pneumonia. Other complications include bedsores and sepsis....more about Creutzfeldt-Jakob Disease »
Symptoms of Creutzfeldt-Jakob Disease
The list of signs and symptoms mentioned in various sources
for Creutzfeldt-Jakob Disease includes the 37
symptoms listed below:
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Creutzfeldt-Jakob Disease: Symptom Checkers
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Creutzfeldt-Jakob Disease: Complications
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Creutzfeldt-Jakob Disease: Undiagnosed Conditions
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Less Common Symptoms of Creutzfeldt-Jakob Disease:
Ocassionally other symptoms may also present themselves as symptoms of Creutzfeldt-Jakob Disease.
of the more common ones are included in the list below:
Wrongly Diagnosed with Creutzfeldt-Jakob Disease?
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that may be on the differential diagnosis list of alternative diagnoses
for Creutzfeldt-Jakob Disease includes:
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Other Possible Causes of these Symptoms
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Article Excerpts About Symptoms of Creutzfeldt-Jakob Disease:
Creutzfeldt-Jakob Disease Fact Sheet: NINDS (Excerpt)
CJD is characterized as a rapidly progressive dementia. Initially,
patients experience problems with muscular coordination; personality
changes, including impaired memory, judgment, and thinking; and impaired
vision. People with the disease also may experience insomnia, depression,
or unusual sensations. CJD does not cause a fever or other flu-like
symptoms. As the illness progresses, the patients' mental impairment
becomes severe. They often develop involuntary muscle jerks called
myoclonus, and they may go blind. They eventually lose the ability to move
and speak and enter a coma. Pneumonia and other infections often occur in
these patients and can lead to death.
There are several known variants of CJD. These variants differ somewhat
in the symptoms and course of the disease. For example, a variant form of
the disease — called new variant or variant (nv-CJD, v-CJD), described in
Great Britain and France — begins primarily with psychiatric symptoms,
affects younger patients than other types of CJD, and has a longer than
usual duration from onset of symptoms to death. Another variant, called
the panencephalopathic form, occurs primarily in Japan and has a
relatively long course, with symptoms often progressing for several years.
Scientists are trying to learn what causes these variations in symptoms
and course of the disease.
Some symptoms of CJD can be similar to symptoms
of other progressive neurological disorders, such as Alzheimer's or
Huntington's disease. However, CJD causes unique changes in brain tissue
which can be seen at autopsy. It also tends to cause more rapid
deterioration of a person's abilities than Alzheimer's disease or most
other types of dementia.
(Source: excerpt from Creutzfeldt-Jakob Disease Fact Sheet: NINDS)
Facts About Creutzfeldt-Jakob Disease: CDC-OC (Excerpt)
Clinical features of CJD include a neurological presentation, with
dementia, and a progressive cerebellar syndrome including ataxia, gait,
and speech abnormalities. In most patients, these symptoms are followed
by involuntary movements and the appearance of a typical diagnostic
(Source: excerpt from Facts About Creutzfeldt-Jakob Disease: CDC-OC)
Update Follow-Up Study of NHPP Growth Hormone Recipients: NIDDK (Excerpt)
CJD does not cause the same symptoms in everyone. Often, the first
signs of CJD in hGH recipients were unsteadiness in walking, dizziness,
clumsiness, and problems with balance. Later, they began to slur their
words, lost muscle control, or had problems with vision, memory, or
thinking clearly. Once symptoms began, the disease advanced quickly. In 2
to 3 months, patients could not walk or do other simple tasks.
Headaches are not a symptom of CJD. Mild symptoms that come and go over
a long period, such as being clumsy, irritable, or forgetful, are not
signs of CJD. (Source: excerpt from Update Follow-Up Study of NHPP Growth Hormone Recipients: NIDDK)
Creutzfeldt-Jakob Disease as a Cause of Symptoms or Medical Conditions
When considering symptoms of Creutzfeldt-Jakob Disease, it is also important to consider Creutzfeldt-Jakob Disease as a possible cause of other medical conditions.
The Disease Database lists the following medical conditions that Creutzfeldt-Jakob Disease may cause:
- (Source - Diseases Database)
Medical articles and books on symptoms:
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About signs and symptoms of Creutzfeldt-Jakob Disease:
The symptom information on this page
attempts to provide a list of some possible signs and symptoms of Creutzfeldt-Jakob Disease.
This signs and symptoms information for Creutzfeldt-Jakob Disease has been gathered from various sources,
may not be fully accurate,
and may not be the full list of Creutzfeldt-Jakob Disease signs or Creutzfeldt-Jakob Disease symptoms.
Furthermore, signs and symptoms of Creutzfeldt-Jakob Disease may vary on an individual basis for each patient.
Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they
are indeed Creutzfeldt-Jakob Disease symptoms.