Glossary for Crohn's disease

• Abdominal Pain: A condition which is characterized by the sensation of pain that is located in the abdomen
• Abdominal abscess: An abscess that occurs anywhere in the abdomen.
• Abdominal cramps: A condition which is characterized by the sensation of muscle cramps that is located in the abdomen
• Abdominal mass: Abdominal swelling with hard mass felt
• Abdominal pain: A condition which is characterized by the sensation of pain that is located in the abdomen
• Abdominal swelling: Swelling or bloating of the abdomen
• Abdominal tenderness: Abdominal point tenderness refers to the pain you feel when pressure is applied to a specific part of the belly area
• Abscess: General name for any pus-filled lump or swelling
• Acute Appendicitis: Infection of the appendix
• Adhesions: A fibrous band or structure by which parts abnormally adhere
• Amebic dysentery: Ameba-caused bacterial bowel infection and ulceration.
• Amyloidosis: A rare group of metabolic disorders where a protein called amyloid accumulates in body organs and tissues where it can cause damage and is potentially fatal. Symptoms depend on the organs involved. There are numerous forms of the condition: primary amyloidosis, secondary amyloidosis, hemodialysis-associated amyloidosis and familial amyloidosis.
• Appendicitis/acute appendicitis/chronic appendicitis:
• Arthritis: General name for any type of joint inflammation, but often means age-related osteoarthritis.
• Autoimmune diseases: A group of disorders in which the primary cause is the an inflammatory reaction caused by the body's own immune system attacking tissues
• Bacterial digestive infections: Bacterial infections affecting the gastrointestinal
• Behcet's Disease: Recurring inflammation of small blood vessels affecting various areas.
• Budesonide -- Teratogenic Agent: There is strong evidence to indicate that exposure to Budesonide during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
• Carcinoid syndrome: Carcinoid heart disease is a rare, metastatic disease that occurs predominantly in the right heart. The tricuspid and pulmonic valves are affected, leading to right heart failure, which results in increased morbidity and mortality.
• Celiac Disease: Digestive intolerance to gluten in the diet.
• Cheilosis: Inflammation of the lips where there is scaling and fissures.
• Chronic Fatigue Syndrome: Severe chronic fatigue disorder often following infection.
• Chronic Pain Syndromes: Any of a variety of disorders that can cause chronic pain of different types.
• Chronic diarrhea: Chronic diarrhea is long-term, ongoing lose, watery and frequent stools.
• Chronic digestive conditions: The chronic digestive conditions include Bowel Cancer, Coeliac Disease, Constipation, Diarrhoea, Diverticular disease, Flatulence, Haemorrhoids, Indigestion and heartburn, Inflammatory Bowel Disease (Crohn's Disease and ulcerative colitis), Irritable Bowel Syndrome, Lactose Intolerance, Ulcers
• Chronic digestive diseases: Any disorder causing ongoing chronic digestive complaints.
• Colitis: Inflammation of the colon
• Collagenous Colitis: A chronic disorder of the digestive system characterized by inflammation and thickening of the large intestine lining.
• Colorectal cancer: Cancer of the colon (bowel) or rectum.
• Crohn's disease: Crohn's disease causes inflammation of the digestive system. It is one of a group of diseases called inflammatory bowel disease. The disease can affect any area from the mouth to the anus. It often affects the lower part of the small intestine called the ileum.
• Cytomegalovirus: A easily transmissible viral infection that is common but generally causes no symptoms except in infants and people with weakened immune systems.
• Diabetic Diarrhea: Diarrhea that occurs in diabetics as a result of the damage done by diabetes to the digestive system. Digestive system damage is caused by intestinal neuropathy (damage to intestinal nerves) or bacterial overgrowth or both.
• Diabetic Gastroparesis: Gastroparesis is a diabetic complication that occurs from neuropathy of the stomach nerve (called the "vagus nerve"). This causes digestive difficulties as the food starts to move too slowly through the stomach.
• Digestive Diseases: Diseases that affect the digestive system
• Digestive symptoms: Any symptoms affecting the digestive tract.
• Diverticular disease and diverticulitis:
• Endometriosis: Misplaced uterus tissue causing scar tissue.
• Enthesopathy: A disease process occurring at locations where tendons and ligaments attach to bone.
• Erythema nodosum: Allergic skin condition usually on the legs
• Eye inflammation: Inflammation of the orbit of the eye
• Eye symptoms: Symptoms affecting the eye
• Fistula: The abnormal passage between two internal organs
• Fractures: Fracture of a bone; also "broken bone".
• Gallstones: Stone-like deposits in the gall bladder.
• Gastrointestinal Basidiobolomycosis: Very rare intestinal infection
• Gastrointestinal bleeding: Internal bleeding in the digestive tract
• Giardia: Contagious parasitic digestive infection
• Glucagonoma: Rare cancer of the glucagon-producing pancreas cells.
• Graves Disease: is an autoimmune disease characterized by hyperthyroidism due to circulating autoantibodies. Thyroid-stimulating immunoglobulins (TSIs) bind to and activate thyrotropin receptors, causing the thyroid gland to grow and the thyroid follicles to increase synthesis of thyroid hormone.
• Immune disorders: Disorders that affect the immune system
• Inflammatory bowel disease: Inflammatory bowel disease refers to digestive symptoms resulting from chronic bowel inflammation. Crohn's disease and ulcerative colitis are two of the main subtypes of the disease. Scientists have discovered an array of genetic mutations which can result in an increased susceptibility to inflammatory bowel disease. Not all people with the genetic anomaly will develop the condition but it can increase the risk especially if other environmental factors are also present. The severity of the disease that develops is variable.
• Intestinal Conditions: Conditions that affect the intestines
• Intestinal blockage: Any blockage that occurs to the gastrointestinal system
• Irritable bowel syndrome: Spasms in the colon wall
• Kaposi's Sarcoma: Kaposi's sarcoma is a cancerous tumor of the connective tissue, and is often associated with AIDS.
• Kidney stones: Kidney stones are solid deposits of salts (e.g calcium) from the urine. These deposits can impair the passage of urine that has the potential to result in infection and kidney damage or failure in severe cases.
• Liver conditions: Any condition that affects the liver
• Lymphocytic colitis: Inflammation of the colon which is only visible through a microscope.
• Malabsorption: Failure to digest nutrients properly
• Malabsorption syndrome: is an alteration in the ability of the intestine to absorb nutrients adequately into the bloodstream
• Mercaptopurine -- Teratogenic Agent: There is evidence to indicate that exposure to Mercaptopurine during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
• Microscopic collagenous colitis: Microscopic collagenous colitis refers to inflammation of the colon that is only visible when the colon's lining is examined under a microscope. The appearance of the inner colon lining in microscopic colitis is normal by visual inspection during colonoscopy or flexible sigmoidoscopy.
• Microscopic lymphocytic colitis: Microscopic lymphocytic colitis refers to inflammation of the colon that is only visible when the colon's lining is examined under a microscope. The appearance of the inner colon lining in microscopic colitis is normal by visual inspection during colonoscopy or flexible sigmoidoscopy.
• Microscopic ulcerative colitis: Microscopic ulcerative colitis refers to inflammation of the colon that is only visible when the colon's lining is examined under a microscope. The appearance of the inner colon lining in microscopic colitis is normal by visual inspection during colonoscopy or flexible sigmoidoscopy.
• Mouth inflammation: Any inflammation that occurs in ones mouth
• Mucus membrane conditions: Medical conditions affecting any of the mucus membranes.
• Osteoporosis: Bone thinning and weakening from bone calcium depletion.
• Pancolitis: Pancolitis is also known as ulcerative colitis which is an idiopathic chronicinflammatory disorder of the colon and rectum and involves the entire thickness of the colon.
• Pelvic Inflammatory Disease: Infection of the womb and fallopian tubes.
• Peptic Ulcer: Ulcer on the lining of the stomach or duodenum
• Peritonitis: Inflammation of the lining of the abdominal cavity
• Proctitis: A chronic inflammatory disease of the rectum which causes bloody diarrhea.
• Protein deficiency:
• Pyoderma Gangrenosum: A rare inflammatory skin disorder characterized by small red bumps or blisters which eventually become ulcerated.
• Reiter’s syndrome: A form of reactive arthritis characterized by arthritis, urethritis, conjunctivitis and skin lesions.
• Rotavirus: Diarrhea-causing virus in infants.
• Schistosomiasis: Parasitic fluke infection in developing countries
• Sexually Transmitted Diseases: Various diseases spread by sexual contact.
• Skin problems: Any condition that affects the skin
• Small Intestine Cancer: Cancer of the small intestine.
• Somatostatinoma: A very rare disorder where tumors in glands that produce somatostatin affect the secretion of the hormone. The tumor mainly occurs in the pancreas but can also occur in the intestinal tract.
• Spondylometaphyseal dysplasia with combined immunodeficiency: A rare syndrome characterized by skeletal abnormalities as well as a poor immune system.
• Tacrolimus -- Teratogenic Agent: There is evidence to indicate that exposure to Tacrolimus during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
• Thalidomide -- Teratogenic Agent: There is evidence to indicate that exposure to Thalidomide during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
• Ulcerative colitis: Ulcerative colitis (Colitis ulcerosa, UC) is a form of inflammatory bowel disease (IBD). Ulcerative colitis is a form of colitis, a disease of the intestine, specifically the large intestine or colon, that includes characteristic ulcers, or open sores, in the colon.
• Ulcerative proctosigmoiditis: Ulcerative proctosigmoiditisis an idiopathic chronicinflammatory disorder limited to the sigmoid colon and the rectum.
• Uveitis: A condition which is characterised by the inflammation of the uvea of the eye
• Vipoma: A rare disorder caused by an increase in secretion of vasoactive intestinal peptide by the pancreas. The syndrome is often caused by an islet-cell tumor (except for beta cells) in the pancreas.
• Vitamin B12 Deficiency: A deficiency of Vitamin B12 primarily causes anemias the body is unable to make sufficient quantities of normal red blood cells. Severe cases can lead to permanent nervous system problems. The vitamin B12 deficiency can result from absorption problems, insufficient dietary intake, certain medications (e.g. metformin), inherited conditions (e.g. transcobalamin deficiency) and certain chronic parasitic intestinal infestations.
• Vitamin deficiency: When there is any deficiency of vitamins in the body
• Weight Gain: An increase in weight for any reason.
• Yersiniosis: A condition which is characterized by infectious diarrhea, enteritis, ileitis and occasionally septicaemia
• Zollinger-Ellison syndrome: A rare disorder where excessive levels of the hormone gastrin are released into the stomach which increases stomach acidity which results in peptic ulcer development. A hormone secreting pancreatic or duodenal tumor is usually the cause.

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