Clinical Trials for Type 1 diabetes

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

• Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
• Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
• Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
• Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Type 1 diabetes is grouped into the following categories:-

• View by trial name
• View by drugs used in Type 1 diabetes clinical trials

Clinical Trials by trial name

The format for each of the following is:

• The name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.
• followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Type 1 diabetes:

• Family Management of Type 1 Diabetes in Children - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Improving Metabolic Assessments in Type 1 Diabetes Mellitus Clinical Trials - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Natural History Study of the Development of Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Telemetric Glucose Data Acquisition During Initiation of Insulin Pump Therapy - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• A Study of Two Versus Three Daily Injections in Children and Adolescents With Newly Diagnosed Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006) - Twice Daily versus Three Times Daily Insulin Injections
• TRIGR - Primary Prevention Study for Type 1 Diabetes in Children at Risk - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pilot Study on the Effect of Oral Controlled-Release Alpha-Lipoic Acid on Oxidative Stress in Adolescents With Type 1 Diabetes Mellitus - This study is no longer recruiting patients (Current: 23 Nov 2006) - controlled-release oral alpha-lipoic acid
• Safety and Efficacy of PEG-Encapsulated Islet Allografts Implanted in Type I Diabetic Recipients - This study is currently recruiting patients (Current: 23 Nov 2006) - Allogeneic Cultured Islet Cells (human); Encapsulated
• Study to Compare Intraperitoneal Insulin to Subcutaneous Insulin Administration in Type 1 Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006)
• Efficacy and Safety of Insulin Glulisine in Type 1 Diabetes Mellitus - This study is no longer recruiting patients (Current: 23 Nov 2006) - insulin glulisine
• Effects of Rituximab on the Progression of Type 1 Diabetes in New Onset Subjects - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Anti-CD20 (rituximab)
• Effects of Vitamin B1 in Type 1 Diabetic Patients - This study is currently recruiting patients (Current: 23 Nov 2006) - Benfotiamine
• hOKT3gamma1 (Ala-Ala) in People Recently Diagnosed With Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - hOKT3gamma1 (Ala-Ala)
• Efficacy of Diazoxide in Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - diazoxide
• Islet Transplantation in Type 1 Diabetics Using the Edmonton Protocol of Steroid Free Immunosuppression - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Type 1 Diabetes Aerobic and Resistance Exercise (T1-DARE) - This study is currently recruiting patients (Current: 23 Nov 2006)
• The Diabetes Prevention Trial of Type 1 Diabetes (DPT-1) - This study has been completed (Current: 23 Nov 2006) - Crystallized human recombinant insulin
• Islet Cell Transplantation Alone in Patients With Type I Diabetes Mellitus: Steroid-Free Immunosuppression - This study has been completed (Current: 23 Nov 2006)
• New Onset of Type 1 Diabetes Mycophenolate Mofetil-Daclizumab Clinical Trial - This study is currently recruiting patients (Current: 23 Nov 2006) - Mycophenolate mofeteil (MMF),Daclizumab (DZB)
• Continuous Glucose Monitors for Children With Diabetes Mellitus - This study has been completed (Current: 23 Nov 2006)
• Pilot Study of the GlucoWatch G2 Biographer for the Management of Type 1 Diabetes in Children - This study has been completed (Current: 23 Nov 2006)
• Randomized Clinical Trial to Assess the Effectiveness of the GlucoWatch Biographer - This study has been completed (Current: 23 Nov 2006)
• Pilot Study of the Navigator Continuous Glucose Monitor - This study is currently recruiting patients (Current: 23 Nov 2006)
• T Cell Validation Study Using Blood Samples From Subjects With Recent Onset Type 1 Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006)
• Nutritional Intervention to Prevent Diabetes - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Docosahexaenoic acid (DHA)
• Pirfenidone to Treat Kidney Disease in Patients With Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - Pirfenidone
• Feasibility Study of 2000 IU Per Day of Vitamin D for the Primary Prevention of Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - vitamin D3 (cholecalciferol) 2000 IU per day
• The Role of Amylin and Glucagon in T1DM - This study is no longer recruiting patients (Current: 23 Nov 2006) - Pramlintide and glucagon
• The Effect of Prolonged Pramlintide Infusion in Pediatric Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - Pramlintide
• A Study in Type 1 Diabetic Patients With Repeated Doses of E1 in Combination With G1 - This study is currently recruiting patients (Current: 23 Nov 2006) - E1 and G1
• Continuous Subcutaneous Infusion of Pramlintide and Insulin - This study is currently recruiting patients (Current: 23 Nov 2006) - Pramlintide
• Trial of Intranasal Insulin in Children and Young Adults at Risk of Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Lunch Time Insulin Injection by School Nurse for Poorly Controlled Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - glargine insulin
• Vascular Function in Adolescent, Diabetic Children - This study is currently recruiting patients (Current: 23 Nov 2006)
• Assessment of Beta Cell Mass in Type 1 Diabetes With 11C-Dihydrotetrabenazine and PET Scan - This study is currently recruiting patients (Current: 23 Nov 2006)
• DIRECT: DIabetic Retinopathy Candesartan Trials. - This study is no longer recruiting patients (Current: 23 Nov 2006) - candsartan cilexetil
• DIRECT: DIabetic Retinopathy Candesartan Trials. - This study is no longer recruiting patients (Current: 23 Nov 2006) - candsartan cilexetil
• Glulisine Pre- and Postmeal - This study has been completed (Current: 23 Nov 2006) - Insulin glulisine
• Safety and Efficacy of INGAP-Peptide in Patients With Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006) - INGAP-Peptide
• Effects of Nurse-Counselling in the Improvement of the type1 Diabetes Control in Adolescents - This study is currently recruiting patients (Current: 23 Nov 2006)
• A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Symlin in Adolescent Subjects With Type 1 Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006) - pramlintide acetate
• The Effect of Cinnamon on HbA1c Among Adolescents With Type I Diabetes - This study has been completed (Current: 23 Nov 2006) - cinnamon
• Interferon-Alpha for Diabetes Mellitus Type 1 - This study is no longer recruiting patients (Current: 23 Nov 2006) - Oral Interferon-Alpha
• Evaluation of a Diabetes Vaccine in Newly Diagnosed Diabetics - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Islet Cell Transplantation Alone and CD34+ Enriched Bone Marrow Cell Infusion in Patients With Diabetes Mellitus: Steroid-Free Regimen - This study has been completed (Current: 23 Nov 2006)
• Insulin NovoRapid Versus Actrapid in Treatment of Type 1 Diabetic Patients During Daily Adjustment of Insulin Dose - This study is no longer recruiting patients (Current: 23 Nov 2006) - Insulin NovoRapid versus Actrapid
• The Effect of Metformin in Overweight Patients With Dysregulated Type 1 Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006) - Tablet Metformin 500 mg
• Umbilical Cord Blood Infusion to Treat Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Study to Estimate the Effects of Inhaled Versus Intravenous (IV) Infusion of Human Insulin in Subjects With Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - Exubera
• Human Islet Transplantation in Brittle Type 1 Diabetes Mellitus. The GRAGIL 2 Study. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Molecular Quantification of Insulin mRNA - This study is currently recruiting patients (Current: 23 Nov 2006)
• Web-Based Follow-Up Using Cellular Phone in Type 1 Diabetic Patients Under Insulin Pump Therapy : The PumpNet Study - This study has been completed (Current: 23 Nov 2006)
• CBT in Adolescents With Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Ingested Interferon Alpha: Prolongation or Permanence of the "Honeymoon" Phase in Newly Diagnosed Type 1 Diabetes Mellitus - This study is no longer recruiting patients (Current: 23 Nov 2006) - interferon alpha
• Single Dose and 34-Day Tolerance Study of INGAP Peptide in Insulin Deficient Patients - This study has been completed (Current: 23 Nov 2006) - INGAP Peptide
• Evaluation of the Bioavailability of Pramlintide - This study has been completed (Current: 23 Nov 2006) - Pramlintide acetate
• Evaluation of Dose-Titration of Pramlintide During Initiation of Therapy in Patients Trying to Improve Glucose Control - This study has been completed (Current: 23 Nov 2006) - Pramlintide acetate
• Evaluation of the Effect of Pramlintide on Satiety and Food Intake - This study has been completed (Current: 23 Nov 2006) - Pramlintide acetate
• Safety and Efficacy of Human Insulin Inhalation Powder in Patients With Type 1 Diabetes Mellitus. - This study has been completed (Current: 23 Nov 2006) - Diabetes Mellitus
• Matrix Metalloproteinases and Diabetic Nephropathy - This study is currently recruiting patients (Current: 23 Nov 2006)
• Islet Transplantation for Patients With Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Study of the Long-Term Safety of Pramlintide in Subjects With Type 1 Diabetes Mellitus - This study is no longer recruiting patients (Current: 23 Nov 2006) - pramlintide acetate
• Comparison of Insulin Detemir Given Once or Twice Daily in Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - Insulin detemir,Insulin aspart
• Effect of Metformin in Patients With Type-1 Diabetes With Inadequate Glycaemic Control by Insulin and Diet - This study is no longer recruiting patients (Current: 23 Nov 2006) - Metformin or placebo
• Diabetes Telemedicine Project - This study is currently recruiting patients (Current: 23 Nov 2006)
• Study of Human Insulin Inhalation Powder in Patients With Type 1 Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006) - Inhaled insulin
• Influence of Binge Drinking on Glucose Metabolism in Patients With Type 1 Diabetes A Pilot Study - This study is currently recruiting patients (Current: 23 Nov 2006)
• European Trial of Immunosuppression in SPK Tx - This study is no longer recruiting patients (Current: 23 Nov 2006) - sirolimus versus mycophenolate mofetil
• To Examine the Lung When People With Diabetes Take an Inhaled Form of Insulin, Compared to Subcutaneous Insulin. - This study is currently recruiting patients (Current: 23 Nov 2006) - Inhaled insulin
• Allogenic Islet Cell Transplantation - This study is currently recruiting patients (Current: 23 Nov 2006) - Allogenic islet cells (human, U. Chicago)
• Comparison of Insulin Detemir With NPH Insulin in Type 1 Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006) - NPH,Insulin Detemir,Insulin Aspart
• Local Registration Trial in China Humalog Mix 50 - This study has been completed (Current: 23 Nov 2006) - Humalog Mix 50
• Outcomes and Cost Consequences of Using an Internet Co-Management Module to Improve the Quality of Type 1 Diabetes Care - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Vascular Reactivity in Diabetic Dialysis Patients. - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• VARIABILITE DETEMIR - Efficacy Study on the Control of Blood Glucose Concentration in Type 1 Diabetic Patients - This study is currently recruiting patients (Current: 23 Nov 2006) - insulin glulisine / insulin glargine / insulin detemir
• Insulin Glargine in Type 1 Diabetes Mellitus - This study is no longer recruiting patients (Current: 23 Nov 2006) - Insulin glargine
• Effect of C-Peptide on Diabetic Peripheral Neuropathy - This study has been completed (Current: 23 Nov 2006) - C-peptide
• Metabolic Effects of Accurate Blood Sugar Results and Education in Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006) - Insulin dosing based on SMBG chart and education
• Islet Cell Transplants for Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• SAM - Skip a Meal - Insulin Glargine, Diabetes Mellitus Type 1 - This study has been completed (Current: 23 Nov 2006) - Insulin glargine
• Islet Cell Transplantation in Patients With Type I Diabetes With Previous Kidney Transplantation - This study is currently recruiting patients (Current: 23 Nov 2006)
• Improving Control and Reducing the Risk of Hypoglycemic Episodes in Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Blood Glucose Awareness Training for Parents - This study is currently recruiting patients (Current: 23 Nov 2006)
• Safety and Efficacy of Inhaled Insulin in Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - insulin human inhalation solution
• Diabetes Technology Study of Real-Time Glucose Alerts in the Team Management of Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• The Effect of Hyperglycaemia on Local Energy Stores in the Working Muscle in Patients With Type 1 Diabetes Mellitus - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• A Clinical Trial Comparing Efficacy and Safety of Exubera and Humalog - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Inhaled Human Insulin (Exubera),Insulin lispro (Humalog)
• Improving Blood Pressure Management in Patients With Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Glargine in Type I Diabetes Mellitus> Main Study "AT.LANTUS": A Trial Comparing Lantus Algorithms to Achieve Normal Blood Glucose Targets in Subjects With Uncontrolled Blood Sugar. Sub-Study: "HALT"(Hypoglycaemia Avoidance With Lantus Trial) - This study has been completed (Current: 23 Nov 2006) - Insulin Glargine
• Insulin Glulisine, Diabetes Mellitus Type 1 - This study is no longer recruiting patients (Current: 23 Nov 2006) - Insulin glulisine
• Breaking Down Barriers to Diabetes Self-Care - This study is currently recruiting patients (Current: 23 Nov 2006)
• Renin Angiotensin System Study (RASS/B-RASS) - This study is no longer recruiting patients (Current: 23 Nov 2006) - enalapril,losartan
• Autoantibodies in Patients With Type 1 Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006)
• Alemtuzumab Induction in Islet Transplantation - This study is currently recruiting patients (Current: 23 Nov 2006) - alemtuzumab
• Islet Transplantation Using Campath-1H and Infliximab Induction - This study is no longer recruiting patients (Current: 23 Nov 2006) - alemtuzumab,infliximab
• Lantus in the Treatment of Type 1 Diabetes Children - This study is currently recruiting patients (Current: 23 Nov 2006) - Lantus and short acting analogs Vs NPH and short acting analogs
• Use of the Paradigm 722 System to Improve Glycemic Control in Adult and Adolescent Subjects With Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Study Comparing Effectiveness of Intraperitoneal Insulin Administration to Subcutaneous Insulin Administration - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Islet Transplantation in Type 1 Diabetic Patients - This study is currently recruiting patients (Current: 23 Nov 2006) - Islet cell and immunosuppression
• Intranasal Insulin for Prevention of Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - daily intranasal administration of insulin
• Treatment Trial Evaluating Long Acting Insulin in Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006) - Basal insulin
• A Comparison of Pharmacodynamics and Pharmacokinetics of Insulin Aspart, Biphasic Insulin Aspart 30, 50 and 70. - This study is currently recruiting patients (Current: 23 Nov 2006) - NovoRapid, NovoMix 30, Bifasisk Insulin Aspart 50, BIAsp70
• hOKT31 (Ala-Ala) Combined With Sirolimus and Delayed Tacrolimus in Type 1 Diabetic Islet Allograft Recipients - This study has been completed (Current: 23 Nov 2006) - Allogeneic Islets of Langerhans,hOKT3γ1 (Ala-Ala)
• Delayed Mycophenolate Mofetil in Single-Donor Islet Allotransplantation in Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006) - Allogeneic Islets of Langerhans
• Medtronic MiniMed Implantable Insulin Pump - This study is no longer recruiting patients (Current: 23 Nov 2006)
• A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Activity of Very Low Dose-Glucagon in Subjects With Type 1 Diabetes Mellitus - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - very low dose (VLD) glucagon
• Safety of Inhaled Insulin With Type 1 and Type 2 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - Inhaled Insulin
• Clinical Islet Transplantation Using the Edmonton Protocol - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Comparison of Efficacy and Safety of Insulin Detemir and Insulin Glargine in Patients With Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006) - Insulin Detemir,Insulin Glargine,Insulin Aspart
• Comparison of Efficacy and Safety of Insulin Detemir and NPH Insulin in Children and Adolescents With Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006) - Insulin Detemir,NPH Insulin,Insulin Aspart
• The Effect of Exercise on Blood Glucose Levels in Patients With Type 1 Diabetes A Comparison of 3 Long-Acting Insulins - This study is currently recruiting patients (Current: 23 Nov 2006) - Insulin Detemir,Insulin Glargine,NPH Insulin
• The Effect of Antihypertensive Drugs on the Retina in Type 1 Diabetes - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Amlodipine,Lisinopril
• Predictive and Protective Factors in the Cause of Diabetes - A Study in Twins - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Management of Type 1 Diabetes Among Adolescents - This study has been completed (Current: 23 Nov 2006)
• Family Management of Childhood Diabetes Study - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Analogues and Severe Hypoglycaemia - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - insulin levemir / aspart,human insulin /insulin isophane
• Rosiglitazone and Insulin in T1DM Adolescents - This study has been completed (Current: 23 Nov 2006) - Rosiglitazone
• Study of Intensive, Home-Based Family Therapy to Improve Illness Management in Youth With Diabetes - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Depression In Juvenile Diabetics - This study has been completed (Current: 23 Nov 2006)
• Markers and Mechanisms of Macrovascular Disease in IDDM - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Epidemiological Study of Cardiovascular Disease in Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Coronary Artery Calcification in Type 1 Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006)
• hOKT3gamma1 (Ala-Ala) for the Prevention of Human Islet Allograft Failure - This study is no longer recruiting patients (Current: 23 Nov 2006) - hOKT3gamma1 (Ala-ala)
• Islet Cell Transplants for Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006) - Sirolimus.,Tacrolimus.,Daclizumab.,Sulfamethoxazole.,Ganciclovir.,Trimethoprim.,Pentamidine
• Risk Factors for Atherogenesis in Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Treatment for Symptomatic Peripheral Neuropathy in Patients With Diabetes - This study has been completed (Current: 23 Nov 2006) - Ruboxistaurin mesylate
• Treatment for Symptomatic Peripheral Neuropathy in Patients With Diabetes - This study has been completed (Current: 23 Nov 2006) - Ruboxistaurin mesylate
• Insulin Aspart Vs. Insulin Lispro Vs. Regular Insulin in Pediatric Population - This study has been completed (Current: 23 Nov 2006) - Insulin Aspart (NovoLog®),Regular Human Insulin (Novolin®R),Insulin Lispro (Humalog®) in combination with NPH
• Safety and Pharmacokinetics (PK) of hOKT3g1 (Ala-Ala) in Type 1 Diabetes Mellitus (T1DM) - This study is no longer recruiting patients (Current: 23 Nov 2006) - hokt3g1 (ALA-ALA)
• Comparison of the Ability of Glulisine With Lispro to Control Type 1 Diabetes Mellitus in Children and Adolescents - This study is currently recruiting patients (Current: 23 Nov 2006) - insulin glulisine,insulin lispro,insulin glargine,NPH insulin
• Ischemic Injury and Ischemic Preconditioning in Diabetes - This study has been suspended (Current: 23 Nov 2006) - Diazoxide,glibenclamide,adenosine
• Prevention of Diabetes Progression Trial (PDPT) - This study has been completed (Current: 23 Nov 2006) - Zenapax
• Solitary Islet Transplantation for Type 1 Diabetes Mellitus Using Steroid Sparing Immunosuppression - This study is no longer recruiting patients (Current: 23 Nov 2006) - Islets
• Clinical Utility and Safety of Pramlintide in Subjects With Type 1 and Type 2 Diabetes Mellitus - This study has been completed (Current: 23 Nov 2006) - pramlintide acetate
• Pediatric Atorvastatin in Diabetes Intervention Trial (PADIT) - This study is currently recruiting patients (Current: 23 Nov 2006) - Atorvastatin 20 mg daily for 3 months
• The Role of Regulatory T Cell in Patients With Type 1 Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006)
• Open Trial of Miglitol in Type 1 Diabetic Patients With Insulin Treatment - This study is no longer recruiting patients (Current: 23 Nov 2006) - Miglitol
• An Observational Study Evaluating SYMLIN (Pramlintide Acetate) Injection Use in Insulin Using Patients With Type 2 and Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - pramlintide acetate
• hOKT31 (Ala-Ala), Sirolimus and Tacrolimus in Islet Transplantation - This study is currently recruiting patients (Current: 23 Nov 2006) - hOKT3 gamma 1 (Ala-Ala),Allogeneic Islets of Langerhans
• Islet Transplantation Using Efalizumab - This study is currently recruiting patients (Current: 23 Nov 2006) - Human Islets,efalizumab
• TEDDY - The Environmental Determinants of Diabetes in the Young - This study is currently recruiting patients (Current: 23 Nov 2006)
• Anti-Thymocyte Globulin, Cyclosporine, and RAD in Islet Transplantation - This study is no longer recruiting patients (Current: 23 Nov 2006) - Allogeneic Islets of Langerhans,Everolimus (RAD)
• Insulin Glulisine in Type 1 Diabetes Mellitus - This study has been completed (Current: 23 Nov 2006) - Insulin Glulisine
• Safety and Efficacy Study of Autologous Stem Cell Transplantation for Early Onset Type I Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006)
• Islet Cell Transplantation Alone and CD34+ Enriched Donor Bone Marrow Cell Infusion in Patients With Type 1 Diabetes Mellitus; Steroid Free Regimen - This study is currently recruiting patients (Current: 23 Nov 2006)
• Steroid-Free and Long-Term Calcineurin-Free Trial in Islet Cell Transplantation - This study is currently recruiting patients (Current: 23 Nov 2006)
• Feasibility and Efficacy of Delivering Blood Glucose Awareness Training Over the Internet - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Gene Expression Profiling in Type 1 Diabetes - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Evaluate the Efficacy of Insulin Patients With Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - Insulin
• Behavior Therapy for Families of Diabetic Adolescents - This study has been completed (Current: 23 Nov 2006)
• Diabetes Control and Complications Trial (DCCT) - This study has been completed (Current: 23 Nov 2006)
• Epidemiology of Diabetes Interventions and Complications (EDIC) - This study has been completed (Current: 23 Nov 2006)
• Prevention of Severe Hypoglycemia in Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006) - insulin glargine
• Anti-CD3 mAb Treatment of Recent Onset Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - mAb hOKT3gamma1(Ala-Ala)
• The Probeta Study - a Multinational Clinical Trial of MGA031 for Preserving the Capability to Produce Insulin, Reducing Insulin Usage and Improving Blood Sugar Levels in Children and Adults With Recent-Onset Type 1 Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006) - MGA031
• African-American Diabetes Intervention Project - This study has been completed (Current: 23 Nov 2006)
• Polyclonal Anti-T-Lymphocyte Globulin in Type-1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - Polyclonal anti-T-cell antibodies
• Maximal Dose of Angiotensin Converting Enzyme (ACE) Inhibitor for Treatment of Diabetic Kidney Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - Lisinopril
• Dose-Exposure-Response in Type 1 Diabetes Mellitus - This study has been completed (Current: 23 Nov 2006) - Insulin glulisine
• Monitoring of Nocturnal Hypoglycemia Using EarlySense Monitoring Device - This study is currently recruiting patients (Current: 23 Nov 2006)
• A Pilot Study to Determine the Safety of Campath-1H (Anti-CD52 Antibody) Therapy in Newly Diagnosed Subjects With Type 1 Diabetes Mellitus - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Campath 1H® (Alemtuzumab)
• Laser and Medical Treatment of Diabetic Macular Edema - This study has been completed (Current: 23 Nov 2006) - Vitamin E
• Effect of AC2993 With or Without Immunosuppression on Beta Cell Function in Patients With Type I Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006) - AC2993
• 12 Week,Comparing Safety of HMR1964 & Insulin Aspart Used in Continuous Subcutaneous Infusion in Type 1 Diabetes. - This study has been completed (Current: 23 Nov 2006) - HMR 1964, Insulin glulisine
• Safety, Tolerability, Immunological and Clinical Efficacy of Multiple Subcutaneous Doses of DiaPep277 in Latent Autoimmune Diabetes in Adults (LADA) - This study is currently recruiting patients (Current: 23 Nov 2006) - DiaPep277
• Safety and Efficacy of Insulin Detemir Plus Insulin Aspart Against Insulin Glargine Plus Insulin Aspart as Mealtime Insulin in Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006) - Insulin Detemir,Insulin Glargine,Insulin Aspart
• Safety and Efficacy of NovoLog Vs. Humalog in Insulin Pumps in Children and Adolescents - This study is no longer recruiting patients (Current: 23 Nov 2006) - Insulin Aspart,Insulin Lispro
• Study to Determine the Relationship Between Exercise and Hypoglycemia in Children With Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• The Effect of Insulin During Exercise on the Development of Low Blood Sugar in Individuals With Type I Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Renal and Peripheral Hemodynamic Function in Patients With Type 1 Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006) - Ruboxistaurin,placebo
• Islet Cell Transplantation Alone in Patients With Type 1 Diabetes Mellitus: Steroid-Free Immunosuppression - This study is currently recruiting patients (Current: 23 Nov 2006)
• Efficacy & Safety of Inhaled Insulin in Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - Inhaled Insulin
• Diabetes Type 1, Treatment Study Atacand/Placebo After Kidney Biopsy - This study is no longer recruiting patients (Current: 23 Nov 2006) - Candesartan,Placebo
• Carnitine Levels and Carnitine Supplementation in Type I Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - Carnitine (drug)
• Study of Alemtuzumab Versus Anti-Thymocyte Globulin to Help Prevent Rejection in Kidney and Pancreas Transplantation - This study is currently recruiting patients (Current: 23 Nov 2006) - Alemtuzumab
• Soy Protein in Early Diabetic Nephropathy - This study has been completed (Current: 23 Nov 2006) - soy protein
• An Intervention Trial for Cardiac Neuropathy in Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - Combination of allopurinol, alpha lipoic acid (ALA), and nicotinamide
• Assessment of Insulin Production From Native Pancreas in Patients With Pancreas Transplants - This study is currently recruiting patients (Current: 23 Nov 2006)
• Autoregulation of Glomerular Filtration Rate in Patients With Type 1 Diabetes During Spironolactone Therapy - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Spironolactone
• CSII in Adolescents With Newly Diagnosed T1D - This study is currently recruiting patients (Current: 23 Nov 2006) - Lantus
• RhVEGF (Telbermin) for Induction of Healing of Chronic, Diabetic Foot Ulcers - This study is no longer recruiting patients (Current: 23 Nov 2006) - rhVEGF (telbermin)
• ASCEND: A Study of Cardiovascular Events iN Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006) - aspirin,Omega-3-acid Ethyl Esters
• Ability to Cope With Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Ability to Cope With Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Long-Term Mortality in Diabetics Undergoing Major Surgery - This study is currently recruiting patients (Current: 23 Nov 2006)

Drugs used in Clinical Trials for Type 1 diabetes

The format for each of the following is:

• The drug,
• followed by the name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Type 1 diabetes:

• AC2993 - Effect of AC2993 With or Without Immunosuppression on Beta Cell Function in Patients With Type I Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Adenosine - Ischemic Injury and Ischemic Preconditioning in Diabetes - This study has been suspended (Current: 23 Nov 2006)
• Alemtuzumab - Alemtuzumab Induction in Islet Transplantation - This study is currently recruiting patients (Current: 23 Nov 2006)
• Alemtuzumab - Islet Transplantation Using Campath-1H and Infliximab Induction - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Alemtuzumab - Study of Alemtuzumab Versus Anti-Thymocyte Globulin to Help Prevent Rejection in Kidney and Pancreas Transplantation - This study is currently recruiting patients (Current: 23 Nov 2006)
• Allogeneic Cultured Islet Cells (human); Encapsulated - Safety and Efficacy of PEG-Encapsulated Islet Allografts Implanted in Type I Diabetic Recipients - This study is currently recruiting patients (Current: 23 Nov 2006)
• Allogeneic Islets of Langerhans - Anti-Thymocyte Globulin, Cyclosporine, and RAD in Islet Transplantation - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Allogeneic Islets of Langerhans - Delayed Mycophenolate Mofetil in Single-Donor Islet Allotransplantation in Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Allogeneic Islets of Langerhans - hOKT31 (Ala-Ala) Combined With Sirolimus and Delayed Tacrolimus in Type 1 Diabetic Islet Allograft Recipients - This study has been completed (Current: 23 Nov 2006)
• Allogeneic Islets of Langerhans - hOKT31 (Ala-Ala), Sirolimus and Tacrolimus in Islet Transplantation - This study is currently recruiting patients (Current: 23 Nov 2006)
• Allogenic islet cells (human, U. Chicago) - Allogenic Islet Cell Transplantation - This study is currently recruiting patients (Current: 23 Nov 2006)
• Amlodipine - The Effect of Antihypertensive Drugs on the Retina in Type 1 Diabetes - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Anti-CD20 (rituximab) - Effects of Rituximab on the Progression of Type 1 Diabetes in New Onset Subjects - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Aspirin - ASCEND: A Study of Cardiovascular Events iN Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Atorvastatin 20 mg daily for 3 months - Pediatric Atorvastatin in Diabetes Intervention Trial (PADIT) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Basal insulin - Treatment Trial Evaluating Long Acting Insulin in Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Benfotiamine - Effects of Vitamin B1 in Type 1 Diabetic Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
• C-peptide - Effect of C-Peptide on Diabetic Peripheral Neuropathy - This study has been completed (Current: 23 Nov 2006)
• Campath 1H® (Alemtuzumab) - A Pilot Study to Determine the Safety of Campath-1H (Anti-CD52 Antibody) Therapy in Newly Diagnosed Subjects With Type 1 Diabetes Mellitus - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Candesartan - Diabetes Type 1, Treatment Study Atacand/Placebo After Kidney Biopsy - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Candsartan Cilexetil - DIRECT: DIabetic Retinopathy Candesartan Trials. - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Candsartan Cilexetil - DIRECT: DIabetic Retinopathy Candesartan Trials. - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Carnitine (drug) - Carnitine Levels and Carnitine Supplementation in Type I Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Cinnamon - The Effect of Cinnamon on HbA1c Among Adolescents With Type I Diabetes - This study has been completed (Current: 23 Nov 2006)
• Combination of allopurinol, alpha lipoic acid (ALA), and nicotinamide - An Intervention Trial for Cardiac Neuropathy in Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Controlled-Release Oral Alpha-Lipoic Acid - Pilot Study on the Effect of Oral Controlled-Release Alpha-Lipoic Acid on Oxidative Stress in Adolescents With Type 1 Diabetes Mellitus - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Crystallized human recombinant insulin - The Diabetes Prevention Trial of Type 1 Diabetes (DPT-1) - This study has been completed (Current: 23 Nov 2006)
• Daclizumab (DZB) - New Onset of Type 1 Diabetes Mycophenolate Mofetil-Daclizumab Clinical Trial - This study is currently recruiting patients (Current: 23 Nov 2006)
• Daclizumab. - Islet Cell Transplants for Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Daily Intranasal Administration Of Insulin - Intranasal Insulin for Prevention of Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• DiaPep277 - Safety, Tolerability, Immunological and Clinical Efficacy of Multiple Subcutaneous Doses of DiaPep277 in Latent Autoimmune Diabetes in Adults (LADA) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Diabetes Mellitus - Safety and Efficacy of Human Insulin Inhalation Powder in Patients With Type 1 Diabetes Mellitus. - This study has been completed (Current: 23 Nov 2006)
• Diazoxide - Efficacy of Diazoxide in Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Diazoxide - Ischemic Injury and Ischemic Preconditioning in Diabetes - This study has been suspended (Current: 23 Nov 2006)
• Docosahexaenoic acid (DHA) - Nutritional Intervention to Prevent Diabetes - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• E1 and G1 - A Study in Type 1 Diabetic Patients With Repeated Doses of E1 in Combination With G1 - This study is currently recruiting patients (Current: 23 Nov 2006)
• Efalizumab - Islet Transplantation Using Efalizumab - This study is currently recruiting patients (Current: 23 Nov 2006)
• Enalapril - Renin Angiotensin System Study (RASS/B-RASS) - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Everolimus (RAD) - Anti-Thymocyte Globulin, Cyclosporine, and RAD in Islet Transplantation - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Exubera - Study to Estimate the Effects of Inhaled Versus Intravenous (IV) Infusion of Human Insulin in Subjects With Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Ganciclovir. - Islet Cell Transplants for Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Glargine Insulin - Lunch Time Insulin Injection by School Nurse for Poorly Controlled Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Glibenclamide - Ischemic Injury and Ischemic Preconditioning in Diabetes - This study has been suspended (Current: 23 Nov 2006)
• HMR 1964, Insulin glulisine - 12 Week,Comparing Safety of HMR1964 & Insulin Aspart Used in Continuous Subcutaneous Infusion in Type 1 Diabetes. - This study has been completed (Current: 23 Nov 2006)
• Hokt3 Gamma 1 (Ala-Ala) - hOKT31 (Ala-Ala), Sirolimus and Tacrolimus in Islet Transplantation - This study is currently recruiting patients (Current: 23 Nov 2006)
• Hokt3γ1 (Ala-Ala) - hOKT31 (Ala-Ala) Combined With Sirolimus and Delayed Tacrolimus in Type 1 Diabetic Islet Allograft Recipients - This study has been completed (Current: 23 Nov 2006)
• Hokt3G1 (Ala-Ala) - Safety and Pharmacokinetics (PK) of hOKT3g1 (Ala-Ala) in Type 1 Diabetes Mellitus (T1DM) - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Hokt3Gamma1 (Ala-Ala) - hOKT3gamma1 (Ala-Ala) for the Prevention of Human Islet Allograft Failure - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Hokt3Gamma1 (Ala-Ala) - hOKT3gamma1 (Ala-Ala) in People Recently Diagnosed With Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Humalog Mix 50 - Local Registration Trial in China Humalog Mix 50 - This study has been completed (Current: 23 Nov 2006)
• Human Insulin /Insulin Isophane - Insulin Analogues and Severe Hypoglycaemia - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Human Islets - Islet Transplantation Using Efalizumab - This study is currently recruiting patients (Current: 23 Nov 2006)
• INGAP Peptide - Single Dose and 34-Day Tolerance Study of INGAP Peptide in Insulin Deficient Patients - This study has been completed (Current: 23 Nov 2006)
• INGAP-Peptide - Safety and Efficacy of INGAP-Peptide in Patients With Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Infliximab - Islet Transplantation Using Campath-1H and Infliximab Induction - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Inhaled Human Insulin (Exubera) - A Clinical Trial Comparing Efficacy and Safety of Exubera and Humalog - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Inhaled Insulin - Efficacy & Safety of Inhaled Insulin in Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Inhaled Insulin - Safety of Inhaled Insulin With Type 1 and Type 2 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Inhaled insulin - Study of Human Insulin Inhalation Powder in Patients With Type 1 Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Inhaled insulin - To Examine the Lung When People With Diabetes Take an Inhaled Form of Insulin, Compared to Subcutaneous Insulin. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Aspart (NovoLog®) - Insulin Aspart Vs. Insulin Lispro Vs. Regular Insulin in Pediatric Population - This study has been completed (Current: 23 Nov 2006)
• Insulin Aspart - Comparison of Efficacy and Safety of Insulin Detemir and Insulin Glargine in Patients With Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Insulin Aspart - Comparison of Efficacy and Safety of Insulin Detemir and NPH Insulin in Children and Adolescents With Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Insulin Aspart - Comparison of Insulin Detemir With NPH Insulin in Type 1 Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Insulin Aspart - Safety and Efficacy of Insulin Detemir Plus Insulin Aspart Against Insulin Glargine Plus Insulin Aspart as Mealtime Insulin in Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Insulin Aspart - Safety and Efficacy of NovoLog Vs. Humalog in Insulin Pumps in Children and Adolescents - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Insulin Detemir - Comparison of Efficacy and Safety of Insulin Detemir and Insulin Glargine in Patients With Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Insulin Detemir - Comparison of Efficacy and Safety of Insulin Detemir and NPH Insulin in Children and Adolescents With Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Insulin Detemir - Comparison of Insulin Detemir With NPH Insulin in Type 1 Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Insulin Detemir - Safety and Efficacy of Insulin Detemir Plus Insulin Aspart Against Insulin Glargine Plus Insulin Aspart as Mealtime Insulin in Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Insulin Detemir - The Effect of Exercise on Blood Glucose Levels in Patients With Type 1 Diabetes A Comparison of 3 Long-Acting Insulins - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Glargine - Comparison of Efficacy and Safety of Insulin Detemir and Insulin Glargine in Patients With Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Insulin Glargine - Comparison of the Ability of Glulisine With Lispro to Control Type 1 Diabetes Mellitus in Children and Adolescents - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Glargine - Insulin Glargine in Type I Diabetes Mellitus> Main Study "AT.LANTUS": A Trial Comparing Lantus Algorithms to Achieve Normal Blood Glucose Targets in Subjects With Uncontrolled Blood Sugar. Sub-Study: "HALT"(Hypoglycaemia Avoidance With Lantus Trial) - This study has been completed (Current: 23 Nov 2006)
• Insulin Glargine - Prevention of Severe Hypoglycemia in Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Insulin Glargine - Safety and Efficacy of Insulin Detemir Plus Insulin Aspart Against Insulin Glargine Plus Insulin Aspart as Mealtime Insulin in Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Insulin Glargine - The Effect of Exercise on Blood Glucose Levels in Patients With Type 1 Diabetes A Comparison of 3 Long-Acting Insulins - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Glulisine / Insulin Glargine / Insulin Detemir - VARIABILITE DETEMIR - Efficacy Study on the Control of Blood Glucose Concentration in Type 1 Diabetic Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Glulisine - Comparison of the Ability of Glulisine With Lispro to Control Type 1 Diabetes Mellitus in Children and Adolescents - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Glulisine - Efficacy and Safety of Insulin Glulisine in Type 1 Diabetes Mellitus - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Insulin Glulisine - Insulin Glulisine in Type 1 Diabetes Mellitus - This study has been completed (Current: 23 Nov 2006)
• Insulin Human Inhalation Solution - Safety and Efficacy of Inhaled Insulin in Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Levemir / Aspart - Insulin Analogues and Severe Hypoglycaemia - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Insulin Lispro (Humalog®) in combination with NPH - Insulin Aspart Vs. Insulin Lispro Vs. Regular Insulin in Pediatric Population - This study has been completed (Current: 23 Nov 2006)
• Insulin Lispro - Comparison of the Ability of Glulisine With Lispro to Control Type 1 Diabetes Mellitus in Children and Adolescents - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin Lispro - Safety and Efficacy of NovoLog Vs. Humalog in Insulin Pumps in Children and Adolescents - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Insulin NovoRapid versus Actrapid - Insulin NovoRapid Versus Actrapid in Treatment of Type 1 Diabetic Patients During Daily Adjustment of Insulin Dose - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Insulin aspart - Comparison of Insulin Detemir Given Once or Twice Daily in Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin detemir - Comparison of Insulin Detemir Given Once or Twice Daily in Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Insulin dosing based on SMBG chart and education - Metabolic Effects of Accurate Blood Sugar Results and Education in Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Insulin glargine - Insulin Glargine in Type 1 Diabetes Mellitus - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Insulin glargine - SAM - Skip a Meal - Insulin Glargine, Diabetes Mellitus Type 1 - This study has been completed (Current: 23 Nov 2006)
• Insulin glulisine - Dose-Exposure-Response in Type 1 Diabetes Mellitus - This study has been completed (Current: 23 Nov 2006)
• Insulin glulisine - Glulisine Pre- and Postmeal - This study has been completed (Current: 23 Nov 2006)
• Insulin glulisine - Insulin Glulisine, Diabetes Mellitus Type 1 - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Insulin lispro (Humalog) - A Clinical Trial Comparing Efficacy and Safety of Exubera and Humalog - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Insulin - Evaluate the Efficacy of Insulin Patients With Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Interferon Alpha - Ingested Interferon Alpha: Prolongation or Permanence of the "Honeymoon" Phase in Newly Diagnosed Type 1 Diabetes Mellitus - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Islet cell and immunosuppression - Islet Transplantation in Type 1 Diabetic Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
• Islets - Solitary Islet Transplantation for Type 1 Diabetes Mellitus Using Steroid Sparing Immunosuppression - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Lantus and short acting analogs Vs NPH and short acting analogs - Lantus in the Treatment of Type 1 Diabetes Children - This study is currently recruiting patients (Current: 23 Nov 2006)
• Lantus - CSII in Adolescents With Newly Diagnosed T1D - This study is currently recruiting patients (Current: 23 Nov 2006)
• Lisinopril - Maximal Dose of Angiotensin Converting Enzyme (ACE) Inhibitor for Treatment of Diabetic Kidney Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
• Lisinopril - The Effect of Antihypertensive Drugs on the Retina in Type 1 Diabetes - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Losartan - Renin Angiotensin System Study (RASS/B-RASS) - This study is no longer recruiting patients (Current: 23 Nov 2006)
• MGA031 - The Probeta Study - a Multinational Clinical Trial of MGA031 for Preserving the Capability to Produce Insulin, Reducing Insulin Usage and Improving Blood Sugar Levels in Children and Adults With Recent-Onset Type 1 Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006)
• Mab Hokt3Gamma1(Ala-Ala) - Anti-CD3 mAb Treatment of Recent Onset Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Metformin or placebo - Effect of Metformin in Patients With Type-1 Diabetes With Inadequate Glycaemic Control by Insulin and Diet - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Miglitol - Open Trial of Miglitol in Type 1 Diabetic Patients With Insulin Treatment - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Mycophenolate mofeteil (MMF) - New Onset of Type 1 Diabetes Mycophenolate Mofetil-Daclizumab Clinical Trial - This study is currently recruiting patients (Current: 23 Nov 2006)
• NPH Insulin - Comparison of Efficacy and Safety of Insulin Detemir and NPH Insulin in Children and Adolescents With Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• NPH Insulin - The Effect of Exercise on Blood Glucose Levels in Patients With Type 1 Diabetes A Comparison of 3 Long-Acting Insulins - This study is currently recruiting patients (Current: 23 Nov 2006)
• NPH insulin - Comparison of the Ability of Glulisine With Lispro to Control Type 1 Diabetes Mellitus in Children and Adolescents - This study is currently recruiting patients (Current: 23 Nov 2006)
• NPH - Comparison of Insulin Detemir With NPH Insulin in Type 1 Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006)
• NovoRapid, NovoMix 30, Bifasisk Insulin Aspart 50, BIAsp70 - A Comparison of Pharmacodynamics and Pharmacokinetics of Insulin Aspart, Biphasic Insulin Aspart 30, 50 and 70. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Omega-3-acid Ethyl Esters - ASCEND: A Study of Cardiovascular Events iN Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Oral Interferon-Alpha - Interferon-Alpha for Diabetes Mellitus Type 1 - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Pentamidine. - Islet Cell Transplants for Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Pirfenidone - Pirfenidone to Treat Kidney Disease in Patients With Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Placebo - Diabetes Type 1, Treatment Study Atacand/Placebo After Kidney Biopsy - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Placebo - Renal and Peripheral Hemodynamic Function in Patients With Type 1 Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006)
• Polyclonal anti-T-cell antibodies - Polyclonal Anti-T-Lymphocyte Globulin in Type-1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pramlintide Acetate - A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Symlin in Adolescent Subjects With Type 1 Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pramlintide Acetate - An Observational Study Evaluating SYMLIN (Pramlintide Acetate) Injection Use in Insulin Using Patients With Type 2 and Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pramlintide Acetate - Clinical Utility and Safety of Pramlintide in Subjects With Type 1 and Type 2 Diabetes Mellitus - This study has been completed (Current: 23 Nov 2006)
• Pramlintide Acetate - Study of the Long-Term Safety of Pramlintide in Subjects With Type 1 Diabetes Mellitus - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Pramlintide acetate - Evaluation of Dose-Titration of Pramlintide During Initiation of Therapy in Patients Trying to Improve Glucose Control - This study has been completed (Current: 23 Nov 2006)
• Pramlintide acetate - Evaluation of the Bioavailability of Pramlintide - This study has been completed (Current: 23 Nov 2006)
• Pramlintide acetate - Evaluation of the Effect of Pramlintide on Satiety and Food Intake - This study has been completed (Current: 23 Nov 2006)
• Pramlintide and glucagon - The Role of Amylin and Glucagon in T1DM - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Pramlintide - Continuous Subcutaneous Infusion of Pramlintide and Insulin - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pramlintide - The Effect of Prolonged Pramlintide Infusion in Pediatric Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Regular Human Insulin (Novolin®R) - Insulin Aspart Vs. Insulin Lispro Vs. Regular Insulin in Pediatric Population - This study has been completed (Current: 23 Nov 2006)
• Rhvegf (Telbermin) - RhVEGF (Telbermin) for Induction of Healing of Chronic, Diabetic Foot Ulcers - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Rosiglitazone - Rosiglitazone and Insulin in T1DM Adolescents - This study has been completed (Current: 23 Nov 2006)
• Ruboxistaurin mesylate - Treatment for Symptomatic Peripheral Neuropathy in Patients With Diabetes - This study has been completed (Current: 23 Nov 2006)
• Ruboxistaurin mesylate - Treatment for Symptomatic Peripheral Neuropathy in Patients With Diabetes - This study has been completed (Current: 23 Nov 2006)
• Ruboxistaurin - Renal and Peripheral Hemodynamic Function in Patients With Type 1 Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006)
• Sirolimus Versus Mycophenolate Mofetil - European Trial of Immunosuppression in SPK Tx - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Sirolimus. - Islet Cell Transplants for Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Soy Protein - Soy Protein in Early Diabetic Nephropathy - This study has been completed (Current: 23 Nov 2006)
• Spironolactone - Autoregulation of Glomerular Filtration Rate in Patients With Type 1 Diabetes During Spironolactone Therapy - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Sulfamethoxazole. - Islet Cell Transplants for Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Tablet Metformin 500 mg - The Effect of Metformin in Overweight Patients With Dysregulated Type 1 Diabetes Mellitus - This study is currently recruiting patients (Current: 23 Nov 2006)
• Tacrolimus. - Islet Cell Transplants for Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Trimethoprim. - Islet Cell Transplants for Diabetes - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Twice Daily versus Three Times Daily Insulin Injections - A Study of Two Versus Three Daily Injections in Children and Adolescents With Newly Diagnosed Type 1 Diabetes - This study has been completed (Current: 23 Nov 2006)
• Very Low Dose (Vld) Glucagon - A Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamic Activity of Very Low Dose-Glucagon in Subjects With Type 1 Diabetes Mellitus - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Vitamin D3 (Cholecalciferol) 2000 Iu Per Day - Feasibility Study of 2000 IU Per Day of Vitamin D for the Primary Prevention of Type 1 Diabetes - This study is currently recruiting patients (Current: 23 Nov 2006)
• Vitamin E - Laser and Medical Treatment of Diabetic Macular Edema - This study has been completed (Current: 23 Nov 2006)
• Zenapax - Prevention of Diabetes Progression Trial (PDPT) - This study has been completed (Current: 23 Nov 2006)

The trial data on this page has been sourced from

• The U.S. National Library of Medicine (NLM) together with ClinicalTrials.gov

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