Cure Research for Diabetes
Cure Research list for Diabetes:
The list of research areas and treatments under analysis mentioned
in various sources for Diabetes
Curable Types of Diabetes
Possibly curable or rare types of Diabetes include:
Rare Types of Diabetes:
Some rare types of Diabetes include:
Latest Treatments for Diabetes
Some of the more recent treatments for Diabetes include:
Treatments for Diabetes
Treatments to consider for Diabetes may include:
Cure Research discussion for Diabetes:
Diabetes Overview: NIDDK (Excerpt)
In recent years, advances in diabetes research have led to better ways
to manage diabetes and treat its complications. Major advances include
- The development of a quick-acting insulin analog.
- Better ways to monitor blood glucose and for people with diabetes to
check their own blood glucose levels.
- Development of external insulin pumps that deliver insulin,
replacing daily injections.
- Laser treatment for diabetic eye disease, reducing the risk of
- Successful transplantation of kidneys and pancreas in people whose
own kidneys fail because of diabetes.
- Better ways of managing diabetes in pregnant women, improving
chances of successful outcomes.
- New drugs to treat type 2 diabetes and better ways to manage this
form of diabetes through weight control.
- Evidence that intensive management of blood glucose reduces and may
prevent development of diabetes complications.
- Demonstration that antihypertensive drugs called ACE
(angiotensin-converting enzyme) inhibitors prevent or delay kidney
failure in people with diabetes.
- Promising results with islet transplantation for type 1 diabetes
reported by the University of Alberta in Canada. A nationwide clinical
trial funded by the NIH and the Juvenile Diabetes Foundation is
currently trying to replicate the Canadian advance.
What Will the Future Bring?
In the future, it may be possible to administer insulin through
inhalers, a pill, or a patch. Devices are also being developed that can
monitor blood glucose levels without having to prick a finger to get a
Researchers continue to search for the cause or causes of diabetes and
ways to prevent and cure the disorder. Scientists are looking for genes
that may be involved in type 1 or type 2 diabetes. Some genetic markers
for type 1 diabetes have been identified, and it is now possible to screen
relatives of people with type 1 diabetes to see if they are at risk.
The Diabetes Prevention Trial--Type 1, sponsored by NIDDK, identifies
relatives at risk for developing type 1 diabetes and treats them with low
doses of insulin or with oral insulin-like agents in the hope of
preventing type 1 diabetes. Similar research is under way at other medical
centers throughout the world. For more information about this trial, call
Transplantation of the pancreas or insulin-producing beta cells offers
the best hope of cure for people with type 1 diabetes. Some pancreas
transplants have been successful. However, people who have transplants
must take powerful drugs to prevent rejection of the transplanted organ.
These drugs are costly and may eventually cause other health problems.
Scientists are working to develop less harmful drugs and better methods
of transplanting beta cells to prevent rejection by the body. Using
techniques of bioengineering, researchers are also trying to create
artificial beta cells that secrete insulin in response to increased
glucose levels in the blood.
Recently, researchers at the University of Alberta in Edmonton, Canada,
announced promising results with islet transplantation in seven patients
with type 1 diabetes. At the time of the report in the New England
Journal of Medicine, all seven patients who had received the
transplant remained free of insulin injections up to 14 months after the
A clinical trial funded by the NIH and the Juvenile Diabetes Foundation
will try to replicate the Edmonton advance. With the insights gained from
this trial and other studies, scientists hope to further refine methods of
islet harvesting and transplantation and learn more about the immune
processes that affect rejection and acceptance of transplanted islets.
For type 2 diabetes, the focus is on ways to prevent diabetes.
Preventive approaches include identifying people at high risk for the
disorder and encouraging them to lose weight, be more physically active,
and follow a healthy eating plan. The Diabetes Prevention Program, another
NIDDK project, focuses on preventing the disorder in high-risk
populations, such as people with impaired fasting glucose, African
Americans, Alaska Natives, American Indians, Asian and Pacific Islander
Americans, Hispanic Americans, or women who have had gestational
Several new drugs were recently developed to treat type 2 diabetes. By
using the oral diabetes medications now available, many people can control
blood glucose levels without insulin injections. Studies are under way to
determine how best to use these drugs to manage type 2 diabetes.
Scientists also are investigating strategies for weight loss in people
with type 2 diabetes.
(Source: excerpt from Diabetes Overview: NIDDK)
Diabetes Control and Complications Trial (DCCT): NIDDK (Excerpt)
The DCCT is a clinical study conducted from 1983 to 1993 by the
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
The study showed that keeping blood glucose levels as close to normal as
possible slows the onset and progression of eye, kidney, and nerve
diseases caused by diabetes. In fact, it demonstrated that any sustained
lowering of blood glucose helps, even if the person has a history of poor
The largest, most comprehensive diabetes study ever conducted, the DCCT
involved 1,441 volunteers with type 1 diabetes and 29 medical centers in
the United States and Canada. Volunteers had diabetes for at least 1 year
but no longer than 15 years. They also were required to have no, or only
early signs of, diabetic eye disease.
The study compared the effects of two treatment regimens--standard
therapy and intensive control--on the complications of diabetes.
Volunteers were randomly assigned to each treatment group. (Source: excerpt from Diabetes Control and Complications Trial (DCCT): NIDDK)
Noninvasive Blood Glucose Monitors: NIDDK (Excerpt)
Over the years, scientists have been trying to find noninvasive ways
for people with diabetes to measure their blood glucose. Most methods of
monitoring blood glucose require a blood sample, usually obtained by using
an automatic lancing device on a finger. Some meters use a blood sample
from a less sensitive area, such as the upper arm, forearm, or thigh. Some
devices use a beam of light instead of a lancet to pierce the skin.
(Source: excerpt from Noninvasive Blood Glucose Monitors: NIDDK)
Pancreatic Islet Transplantation: NIDDK (Excerpt)
In pancreatic islet transplantation, cells are taken from a donor
pancreas and transferred into another person. Once implanted, the new
islets begin to make and release insulin. Researchers hope that islet
transplantation will help people with type 1 diabetes live without daily
injections of insulin. (Source: excerpt from Pancreatic Islet Transplantation: NIDDK)
Diabetes: NWHIC (Excerpt)
In recent years, advances in diabetes research have led to better ways
to manage diabetes and treat its complications. For example, the insulin
pump, new oral medications, and better ways of monitoring blood glucose
have become available. In the future, it may be possible to administer
insulin through inhalers, a pill, or a patch. Devices are also being
developed that can monitor blood glucose levels without having to prick a
finger to get a blood sample. Researchers continue to search for the cause
or causes of diabetes and ways to prevent and cure the disorder. (Source: excerpt from Diabetes: NWHIC)
Medical research for Diabetes: medical news summaries:
The following medical news items
are relevant to medical research for Diabetes:
Clinical Trials for Diabetes
Some of the clinical trials for Diabetes include:
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