Down's syndrome associated Celiac Disease: Patients with Down's syndrome have a high degree of susceptibility to developing celiac disease. Up to 17% of Down's syndrome sufferers develop celiac disease but this rate varies amongst age groups and country of origin. Celiac disease is an autoimmune disorder characterized by intolerance to gluten by the small intestine. The type and severity of symptoms varies amongst people - some people have severe gastrointestinal symptoms from infancy whereas other have no symptoms other than fatigue or anemia during adulthood. More detailed information about the symptoms, causes, and treatments of Down's syndrome associated Celiac Disease is available below.
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Prognosis for Down's syndrome associated Celiac Disease: Delayed diagnosis can have long-term negative effects on children's growth and development. Diagnosed patients who can completely avoid gluten have a good prognosis. This can be difficult as gluten is used in a wide range of foods and ingesting even a small amount can cause symptoms. Strict avoidance of gluten means a normal life expectancy can be expected. However, up to 10% of people may eventually develop gastrointestinal cancers which can affect life expectancy.
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