Clinical Trials for Eczema

Clinical trials are research studies conducted in an effort to improve overall patient health and care. Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition. Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks. A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.

A brief description of each phase:

• Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
• Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
• Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
• Phase IV: These studies monitor long-term side effects after the treatment has been marketed.

Clinical Trials data for Eczema is grouped into the following categories:-

• View by trial name
• View by drugs used in Eczema clinical trials

Clinical Trials by trial name

The format for each of the following is:

• The name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.
• followed by a list of drug/s, if any, used in the trial

ClinicalTrials.gov has listed the following trials for Eczema:

• Preliminary Study of Safety and Efficacy of Nanocrystalline Silver Cream in Atopic Dermatitis (Eczema) - This study has been completed (Current: 23 Nov 2006) - Nanocrystalline silver cream (NPI)
• Neuroskin Forte for Dry Skin Relief in Eczema and Psoriasis - This study is currently recruiting patients (Current: 23 Nov 2006) - Neuroskin Forte and Placebo Application
• Influence of Probiotics on Prevention of Atopy, Atopic Disease and Immunological Responses - This study is currently recruiting patients (Current: 23 Nov 2006) - Bifidobacterium longum,Lactobacillus rhamnosus GG
• Promoting Tolerance to Peanut in High-Risk Children - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
• Influence of Probiotics on Atopy, Immunological Responses and Gut Microflora - Follow-Up to 5 Years - This study is currently recruiting patients (Current: 23 Nov 2006) - Bifidobacterium longum,Lactobacillus rhamnosus GG
• Randomized Phase III Study to Evaluate the Efficacy and Safety of Xyzal (Levocetirizine) Vs Zyrtec (Cetirizine) in Subjects With Dermatitis and Eczema - This study has been completed (Current: 23 Nov 2006) - Levocetirizine and Cetirizine
• Double-Blind, Parallel, Randomised Study to Investigate the Effect of Oral Probiotics in Infants With Atopic Dermatitis - This study is no longer recruiting patients (Current: 23 Nov 2006) - probiotics: Lactobacillus GG, lactobacillus Rhamnosus
• NAET Screening for Food Allergy, Sensitivity and Intolerances Using IgE-Specific Antigen Test and NST- NAET - This study has been completed (Current: 23 Nov 2006)
• Nutrition, Allergy, Mucosal Immunology and Intestinal Microbiota: The Effects of Maternal Nutrition During Pregnancy and Breast Feeding on the Risk of Allergic Disease in Child - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pimecrolimus Cream 1% in Patients (18 Years of Age and Over) With Mild to Moderate Chronic Hand Dermatitis - This study has been completed (Current: 23 Nov 2006) - Pimecrolimus Cream 1%
• Study of Clinical Features and Genetics of Hyperimmunoglobulin E Recurrent Infection (Job Syndrome) - This study is currently recruiting patients (Current: 23 Nov 2006)
• Use of a Probiotic Supplement to Prevent Asthma in Infants - This study is currently recruiting patients (Current: 23 Nov 2006) - Probiotic Supplement
• Efalizumab for Eczema - This study is currently recruiting patients (Current: 23 Nov 2006) - Efalizumab treatment
• Histamine Pharmacogenetics in Children With Atopic Dermatitis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Quality of Life Study in Adults With Facial Eczema - This study is no longer recruiting patients (Current: 23 Nov 2006) - Pimecrolimus Cream 1%
• Safety and Efficacy of a Retinoid for the Treatment of Severe Chronic Hand Dermatitis - This study is currently recruiting patients (Current: 23 Nov 2006) - alitretinoin
• Topical NF-kappaB Decoy in the Treatment of Atopic Dermatitis - This study is currently recruiting patients (Current: 23 Nov 2006) - NF-kappaB Decoy
• A Multi-Center Study of Short and Long-Term Use of Protopic Ointment in Patients With Atopic Dermatitis - This study is no longer recruiting patients (Current: 23 Nov 2006) - topical tacrolimus (Protopic Ointment)
• Reconstitution With Pimecrolimus Cream 1% of Steroid-Damaged Skin in Adults With Atopic Dermatitis. - This study is currently recruiting patients (Current: 23 Nov 2006) - Pimecrolimus
• Steroid-Sparing Effect With Pimecrolimus in Pediatric Patients With Atopic Dermatitis - Could not be determined (Current: 23 Nov 2006)
• Efficacy and Safety of Pimecrolimus Cream 1% in Patients 3 Months of Age With Mild or Moderate Atopic Dermatitis - This study is no longer recruiting patients (Current: 23 Nov 2006) - Pimecrolimus Cream 1%

Drugs used in Clinical Trials for Eczema

The format for each of the following is:

• The drug,
• followed by the name of the trial,
• followed by whether the trial is recruiting patients,
  - The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
  - Note**: Please follow the link to determine the current trial status.

ClinicalTrials.gov has listed the following drugs in trials for Eczema:

• Alitretinoin - Safety and Efficacy of a Retinoid for the Treatment of Severe Chronic Hand Dermatitis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Bifidobacterium longum - Influence of Probiotics on Atopy, Immunological Responses and Gut Microflora - Follow-Up to 5 Years - This study is currently recruiting patients (Current: 23 Nov 2006)
• Bifidobacterium longum - Influence of Probiotics on Prevention of Atopy, Atopic Disease and Immunological Responses - This study is currently recruiting patients (Current: 23 Nov 2006)
• Efalizumab treatment - Efalizumab for Eczema - This study is currently recruiting patients (Current: 23 Nov 2006)
• Lactobacillus rhamnosus GG - Influence of Probiotics on Atopy, Immunological Responses and Gut Microflora - Follow-Up to 5 Years - This study is currently recruiting patients (Current: 23 Nov 2006)
• Lactobacillus rhamnosus GG - Influence of Probiotics on Prevention of Atopy, Atopic Disease and Immunological Responses - This study is currently recruiting patients (Current: 23 Nov 2006)
• Levocetirizine and Cetirizine - Randomized Phase III Study to Evaluate the Efficacy and Safety of Xyzal (Levocetirizine) Vs Zyrtec (Cetirizine) in Subjects With Dermatitis and Eczema - This study has been completed (Current: 23 Nov 2006)
• NF-kappaB Decoy - Topical NF-kappaB Decoy in the Treatment of Atopic Dermatitis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Nanocrystalline silver cream (NPI) - Preliminary Study of Safety and Efficacy of Nanocrystalline Silver Cream in Atopic Dermatitis (Eczema) - This study has been completed (Current: 23 Nov 2006)
• Neuroskin Forte and Placebo Application - Neuroskin Forte for Dry Skin Relief in Eczema and Psoriasis - This study is currently recruiting patients (Current: 23 Nov 2006)
• Pimecrolimus Cream 1% - Efficacy and Safety of Pimecrolimus Cream 1% in Patients 3 Months of Age With Mild or Moderate Atopic Dermatitis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Pimecrolimus Cream 1% - Pimecrolimus Cream 1% in Patients (18 Years of Age and Over) With Mild to Moderate Chronic Hand Dermatitis - This study has been completed (Current: 23 Nov 2006)
• Pimecrolimus Cream 1% - Quality of Life Study in Adults With Facial Eczema - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Pimecrolimus - Reconstitution With Pimecrolimus Cream 1% of Steroid-Damaged Skin in Adults With Atopic Dermatitis. - This study is currently recruiting patients (Current: 23 Nov 2006)
• Probiotic Supplement - Use of a Probiotic Supplement to Prevent Asthma in Infants - This study is currently recruiting patients (Current: 23 Nov 2006)
• Probiotics: Lactobacillus Gg, Lactobacillus Rhamnosus - Double-Blind, Parallel, Randomised Study to Investigate the Effect of Oral Probiotics in Infants With Atopic Dermatitis - This study is no longer recruiting patients (Current: 23 Nov 2006)
• Topical Tacrolimus (Protopic Ointment) - A Multi-Center Study of Short and Long-Term Use of Protopic Ointment in Patients With Atopic Dermatitis - This study is no longer recruiting patients (Current: 23 Nov 2006)

The trial data on this page has been sourced from

• The U.S. National Library of Medicine (NLM) together with ClinicalTrials.gov

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