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Clinical Trials for Esophagitis
Clinical trials are research studies conducted in an effort to improve overall patient health and care.
Each trial involves running supervised tests to determine the effectiveness and safety of new drugs, procedures and/or devices with the aim of answering scientific questions about a disease or condition.
Risks and side-effects are also evaluated during these trials with results ranging from being unpleasant, with side effects such as headaches, to more serious or even life-threatening risks.
A clinical trial may be separated into phases, or steps, with each step designed to answer a separate research question. This maybe reflected in the trial name.
A brief description of each phase:
- Phase I: Usually designed to evaluate safety, determine a safe dosage range, and identify side effects on a small group of patients.
- Phase II: If Phase I is successful, the trial is then repeated with a larger group to further evaluate its effect and safety.
- Phase III: Trials are conducted on an ever larger group and are compared with the best current treatment while gathering more information on effect and safety.
- Phase IV: These studies monitor long-term side effects after the treatment has been marketed.
Clinical Trials data for Esophagitis is grouped into the following categories:-
The format for each of the following is:
- The name of the trial,
- followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
- followed by a list of drug/s, if any, used in the trial
ClinicalTrials.gov has listed the following trials for Esophagitis:
- A Study to Compare the Efficacy and Safety of TAK-390MR (30 mg and 60 mg) and Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis. - This study is currently recruiting patients (Current: 23 Nov 2006) - TAK-390MR 30 mg oral,TAK-390MR 60 mg oral
- NEXIUM in the Treatment of Moderate and Severe Erosive Esophagitis - This study is no longer recruiting patients (Current: 23 Nov 2006) - esomeprazole magnesium (oral medication)
- 24 Hour Esophageal and Electrogastrography to Investigate the Mechanism of Reflux Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Immunologic Factors in Reflux Esophagitis and Barretts Esophagus - This study is currently recruiting patients (Current: 23 Nov 2006)
- Efficiency Study of S-Tenatoprazole-Na to Treat Erosive or Ulcerative Esophagitis. - This study has been suspended (Current: 23 Nov 2006) - S-Tenatoprazole-Na (STU-Na)
- Esomeprazole for Treatment of GERD in Pediatric Patients - This study is no longer recruiting patients (Current: 23 Nov 2006) - Esomeprazole
- Intravenous (IV) Pantoprazole in Erosive Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006) - pantoprazole
- A Study to Evaluate the Effects of Intravenous or Oral Lansoprazole on Gastric Acid Secretion in Subjects With Erosive Esophagitis. - This study has been completed (Current: 23 Nov 2006) - Lansoprazole IV and Oral
- The Effect of Nexium on Transmucosal Esophageal Leak - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - Esomeprazole (Nexium) 40 mg/day
- Study to Identify Non-Invasive Markers of Gastrointestinal Allergy - This study is currently recruiting patients (Current: 23 Nov 2006)
- Intravenous Mepolizumab In Children With Eosinophilic Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006) - mepolizumab
- A Pilot Study of the Treatment of Eosinophilic Esophagitis With Omalizumab - This study is currently recruiting patients (Current: 23 Nov 2006) - omalizumab
- Comparison of Esomeprazole to Aerosolized, Swallowed Fluticasone for Eosinophilic Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006) - esomeprazole,fluticasone
- Prospective Analysis of Eosinophilic Esophagitis in Patients Presenting With Dysphagia - This study is currently recruiting patients (Current: 23 Nov 2006)
- A Study to Compare the Efficacy and Safety of TAK-390MR and Lansoprazole on Healing of Erosive Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006) - Tak-390MR oral / Lansoprazole oral
- A Study to Compare the Efficacy and Safety of TAK-390MR and Lansoprazole on Healing of Erosive Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006) - TAK-390MR oral / Lansoprazole oral
- A Study to Compare the Efficacy and Safety of TAK-390MR and Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis - This study is no longer recruiting patients (Current: 23 Nov 2006) - TAK-390MR oral
- A Study to Compare the Efficacy and Safety of TAK-390MR and Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis - This study is no longer recruiting patients (Current: 23 Nov 2006) - TAK-390MR oral
- A Study Comparing Swallowed Flovent and Placebo in Patients With Eosinophilic Disorders - This study is no longer recruiting patients (Current: 23 Nov 2006) - Fluticasone Propionate
- Data Bank for Eosinophilic Disorders - This study is currently recruiting patients (Current: 23 Nov 2006)
- Budesonide for Eosinophilic Esophagitis: a Randomized, Placebo-Controlled, Double-Blind Treatment Study - This study is currently recruiting patients (Current: 23 Nov 2006) - Budesonide
- An Evaluation Of Mepolizumab In Therapy Of Eosinophilic Esophagitis In Adult Patients - This study is currently recruiting patients (Current: 23 Nov 2006) - mepolizumab
- Subcutaneous Amifostine (Ethyol) in the Prevention of Radiochemotherapy-Induced Esophagitis and Pneumonitis in Patients With Unresectable Non-Small Cell Lung Cancer - This study is currently recruiting patients (Current: 23 Nov 2006) - Amifostine
- Study Comparing a Pantoprazole Formulation to the Currently Marketed Tablet for GERD and Erosive Esophagitis - This study is no longer recruiting patients (Current: 23 Nov 2006) - Pantoprazole for approximately 9 weeks
- Dose-Effect of S-Tenatoprazole-Na(STU-Na) 30 mg, 60 mg, 90 mg and 120 mg in Healthy Volunteers - This study is not yet open for patient recruitment (Current: 23 Nov 2006) - S-Tenatoprazole-Na (STU-Na)
- Anti-IL-5 Study for Hypereosinophilic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006) - Mepolizumab
- Topical Steroid Treatment for Eosinophilic Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006) - Swallowed Fluticansone
- A Dose-Finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients With Erosive Esophagitis. - This study has been completed (Current: 23 Nov 2006) - AZD0865
- A Dose-Finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients Without Erosive Esophagitis. - This study has been completed (Current: 23 Nov 2006) - AZD0865
- Evaluation of Amphotericin B in the Treatment of Biopsy Proven Candida Esophagitis in Immunocompromised Patients - This study has been completed (Current: 23 Nov 2006) - Amphotericin B
- A Comparison of Fluconazole and Ketoconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems - This study has been completed (Current: 23 Nov 2006) - Ketoconazole,Fluconazole
- A Study of Fluconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems - This study has been completed (Current: 23 Nov 2006) - Fluconazole
- A Randomized, Prospective, Double-Blind Study Comparing Fluconazole With Placebo for Primary and Secondary Prophylaxis of Mucosal Candidiasis in HIV-Infected Women - This study is no longer recruiting patients (Current: 23 Nov 2006) - Fluconazole
- Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis. - This study has been completed (Current: 23 Nov 2006) - Itraconazole,Fluconazole
- A Study of the Side Effects of L-743,872 in Men With Candidal Esophagitis - This study has been completed (Current: 23 Nov 2006) - L-743,872
- Quantifying Effects of Treatment of Pediatric Dysphonia - This study is currently recruiting patients (Current: 23 Nov 2006) - lansoprazole
- HEARD (Long Term) Study Histology of the Esophagus in Acid-Related Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - Esomeprazole
- Sopran - Omeprazole Treatment Versus Surgery - This study is no longer recruiting patients (Current: 23 Nov 2006) - Omeprazole
- Verification Study on Lafutidine in Mild Reflux Oesophagitis - Double Blind Controlled Study With Famotidine - - This study is currently recruiting patients (Current: 23 Nov 2006) - lafutidine
- ASTERIX: Low Dose ASA and Nexium - This study has been completed (Current: 23 Nov 2006) - Esomeprazole
The format for each of the following is:
- The drug,
- followed by the name of the trial,
- followed by whether the trial is recruiting patients,
- The trial may not have started and not yet recruiting, or the trial may have started and do not need any more recruitements, or the trial may be completed.
- Note**: Please follow the link to determine the current trial status.
ClinicalTrials.gov has listed the following drugs in trials for Esophagitis:
- AZD0865 - A Dose-Finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients With Erosive Esophagitis. - This study has been completed (Current: 23 Nov 2006)
- AZD0865 - A Dose-Finding Phase IIb Study With AZD0865 and Esomeprazole in GERD Patients Without Erosive Esophagitis. - This study has been completed (Current: 23 Nov 2006)
- Amifostine - Subcutaneous Amifostine (Ethyol) in the Prevention of Radiochemotherapy-Induced Esophagitis and Pneumonitis in Patients With Unresectable Non-Small Cell Lung Cancer - This study is currently recruiting patients (Current: 23 Nov 2006)
- Amphotericin B - Evaluation of Amphotericin B in the Treatment of Biopsy Proven Candida Esophagitis in Immunocompromised Patients - This study has been completed (Current: 23 Nov 2006)
- Budesonide - Budesonide for Eosinophilic Esophagitis: a Randomized, Placebo-Controlled, Double-Blind Treatment Study - This study is currently recruiting patients (Current: 23 Nov 2006)
- Esomeprazole (Nexium) 40 mg/day - The Effect of Nexium on Transmucosal Esophageal Leak - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
- Esomeprazole Magnesium (Oral Medication) - NEXIUM in the Treatment of Moderate and Severe Erosive Esophagitis - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Esomeprazole - ASTERIX: Low Dose ASA and Nexium - This study has been completed (Current: 23 Nov 2006)
- Esomeprazole - Comparison of Esomeprazole to Aerosolized, Swallowed Fluticasone for Eosinophilic Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Esomeprazole - Esomeprazole for Treatment of GERD in Pediatric Patients - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Esomeprazole - HEARD (Long Term) Study Histology of the Esophagus in Acid-Related Disease - This study is currently recruiting patients (Current: 23 Nov 2006)
- Fluconazole - A Comparison of Fluconazole and Ketoconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems - This study has been completed (Current: 23 Nov 2006)
- Fluconazole - A Randomized, Prospective, Double-Blind Study Comparing Fluconazole With Placebo for Primary and Secondary Prophylaxis of Mucosal Candidiasis in HIV-Infected Women - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Fluconazole - A Study of Fluconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems - This study has been completed (Current: 23 Nov 2006)
- Fluconazole - Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis. - This study has been completed (Current: 23 Nov 2006)
- Fluticasone Propionate - A Study Comparing Swallowed Flovent and Placebo in Patients With Eosinophilic Disorders - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Fluticasone - Comparison of Esomeprazole to Aerosolized, Swallowed Fluticasone for Eosinophilic Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Itraconazole - Randomized, Controlled, Double-Blind Study of Itraconazole Oral Solution Versus Fluconazole Tablets for the Treatment of Esophageal Candidiasis. - This study has been completed (Current: 23 Nov 2006)
- Ketoconazole - A Comparison of Fluconazole and Ketoconazole in the Treatment of Fungal Infections of the Throat in Patients With Weakened Immune Systems - This study has been completed (Current: 23 Nov 2006)
- L-743,872 - A Study of the Side Effects of L-743,872 in Men With Candidal Esophagitis - This study has been completed (Current: 23 Nov 2006)
- Lafutidine - Verification Study on Lafutidine in Mild Reflux Oesophagitis - Double Blind Controlled Study With Famotidine - - This study is currently recruiting patients (Current: 23 Nov 2006)
- Lansoprazole IV and Oral - A Study to Evaluate the Effects of Intravenous or Oral Lansoprazole on Gastric Acid Secretion in Subjects With Erosive Esophagitis. - This study has been completed (Current: 23 Nov 2006)
- Lansoprazole - Quantifying Effects of Treatment of Pediatric Dysphonia - This study is currently recruiting patients (Current: 23 Nov 2006)
- Mepolizumab - An Evaluation Of Mepolizumab In Therapy Of Eosinophilic Esophagitis In Adult Patients - This study is currently recruiting patients (Current: 23 Nov 2006)
- Mepolizumab - Anti-IL-5 Study for Hypereosinophilic Syndrome - This study is currently recruiting patients (Current: 23 Nov 2006)
- Mepolizumab - Intravenous Mepolizumab In Children With Eosinophilic Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006)
- Omalizumab - A Pilot Study of the Treatment of Eosinophilic Esophagitis With Omalizumab - This study is currently recruiting patients (Current: 23 Nov 2006)
- Omeprazole - Sopran - Omeprazole Treatment Versus Surgery - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Pantoprazole for approximately 9 weeks - Study Comparing a Pantoprazole Formulation to the Currently Marketed Tablet for GERD and Erosive Esophagitis - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Pantoprazole - Intravenous (IV) Pantoprazole in Erosive Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006)
- S-Tenatoprazole-Na (STU-Na) - Dose-Effect of S-Tenatoprazole-Na(STU-Na) 30 mg, 60 mg, 90 mg and 120 mg in Healthy Volunteers - This study is not yet open for patient recruitment (Current: 23 Nov 2006)
- S-Tenatoprazole-Na (STU-Na) - Efficiency Study of S-Tenatoprazole-Na to Treat Erosive or Ulcerative Esophagitis. - This study has been suspended (Current: 23 Nov 2006)
- Swallowed Fluticansone - Topical Steroid Treatment for Eosinophilic Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006)
- TAK-390MR 30 mg oral - A Study to Compare the Efficacy and Safety of TAK-390MR (30 mg and 60 mg) and Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis. - This study is currently recruiting patients (Current: 23 Nov 2006)
- TAK-390MR 60 mg oral - A Study to Compare the Efficacy and Safety of TAK-390MR (30 mg and 60 mg) and Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis. - This study is currently recruiting patients (Current: 23 Nov 2006)
- TAK-390MR oral / Lansoprazole oral - A Study to Compare the Efficacy and Safety of TAK-390MR and Lansoprazole on Healing of Erosive Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006)
- TAK-390MR oral - A Study to Compare the Efficacy and Safety of TAK-390MR and Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis - This study is no longer recruiting patients (Current: 23 Nov 2006)
- TAK-390MR oral - A Study to Compare the Efficacy and Safety of TAK-390MR and Placebo on the Ability to Maintain Healing in Subjects With Healed Erosive Esophagitis - This study is no longer recruiting patients (Current: 23 Nov 2006)
- Tak-390MR oral / Lansoprazole oral - A Study to Compare the Efficacy and Safety of TAK-390MR and Lansoprazole on Healing of Erosive Esophagitis - This study is currently recruiting patients (Current: 23 Nov 2006)
The trial data on this page has been sourced from
