Ewing's sarcoma: Ewing's sarcoma is a malignant round-cell tumor. It is a rare disease in which cancer cells are found in the bone or in soft tissue. The most common areas in which it occurs are the pelvis, the femur, the humerus, and the ribs. More detailed information about the symptoms, causes, and treatments of Ewing's sarcoma is available below.
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Prognosis for Ewing's sarcoma: Five-year survival for localized disease is 70% to 80% when treated with chemotherapy. Long term survival for metastatic disease can be less than 10% but some sources state it is 25-30%
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The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.
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A spectrum of malignant tumors, affecting mostly males under age 20, characterized morphologically by the presence of small round cells. Ewing's sarcoma and peripheral primitive neuroectodermal tumor represent the ends of a spectrum, with Ewing's sarcoma lacking evidence of neural differentiation and the markers that characterize the peripheral primitive neuroectodermal tumor. Ewing's sarcoma and peripheral primitive neuroectodermal tumor may share cytogenetic abnormalities, proto-oncogene expression, cell culture and immunohistochemical abnormalities. These tumors may occur in the soft tissues or the bones. Pain and the presence of a mass are the most common clinical symptoms. -- 2004 - (Source - Diseases Database)
Malignant tumor in bone marrow (usually in the pelvis or in long bones) - (Source - WordNet 2.1)
Ewing's sarcoma is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Ewing's sarcoma, or a subtype of Ewing's sarcoma,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
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