More causes:see full list of causes for Gallstones
Causes of Gallstones (Diseases Database):
The follow list shows some of the possible medical causes of Gallstones
that are listed by the Diseases Database:
Source: Diseases Database
Gallstones Causes: Risk Factors
The following conditions have been cited in various
sources as potentially causal risk factors
related to Gallstones:
Race Patterns for Gallstones Causes:
Racial Information for Gallstones: Native Americans have the highest prevalence of
gallstones in the United States. Among the Pima Indians... (Source: excerpt from Native American Women's Health: NWHIC)
Gallstones Causes: Male-Female Gender Ratio
Gender of Patients for Gallstones: women 2:1 men...more »
Gallstones: Related Medical Conditions
To research the causes of Gallstones, consider researching the causes of these
these diseases that may be similar, or associated with Gallstones:
Gallstones: Causes and Types
Causes of Types of Gallstones: Review the cause informationfor the various types of Gallstones:
- Silent gallstones - unknown gallstones without symptoms
- Symptomatic gallstones - causing symptoms
- Cholesterol stones - about 80% of cases
- Pigment stones
- Mixed stones
- more types...»
Causes of Broader Categories of Gallstones: Review the causal information about the various more general categories of medical conditions:
Gallstones as a complication of other conditions:
Other conditions that might have
Gallstones as a complication may,
potentially, be an underlying cause of Gallstones.
Our database lists the following as having
Gallstones as a complication of that condition:
Gallstones as a symptom:
Conditions listing Gallstones
as a symptom may also be potential underlying causes of Gallstones.
Our database lists the following as having
Gallstones as a symptom of that condition:
Medications or substances causing Gallstones:
The following drugs, medications, substances or toxins are some of the possible
causes of Gallstones as a symptom.
This list is incomplete and various other drugs or substances
may cause your symptoms.
Always advise your doctor of any medications or treatments you are using,
including prescription, over-the-counter, supplements, herbal or alternative treatments.
See full list of 21
medications causing Gallstones
What causes Gallstones?
Article excerpts about the
causes of Gallstones:
Gallstones: NIDDK (Excerpt)
cholesterol stones form when bile contains too much cholesterol, too much
bilirubin, or not enough bile salts, or when the gallbladder does not
empty as it should for some other reason.
The cause of pigment stones is uncertain. They
tend to develop in people who have cirrhosis, biliary tract infections,
and hereditary blood disorders such as sickle cell anemia.
It is believed that the mere presence of
gallstones may cause more gallstones to develop. However, other factors
that contribute to gallstones have been identified, especially for
(Source: excerpt from Gallstones: NIDDK)
- Obesity. Obesity is a major risk factor for gallstones,
especially in women. A large clinical study showed that being even
moderately overweight increases one's risk for developing gallstones.
The most likely reason is that obesity tends to reduce the amount of
bile salts in bile, resulting in more cholesterol. Obesity also
decreases gallbladder emptying.
- Estrogen. Excess estrogen from pregnancy, hormone replacement
therapy, or birth control pills appears to increase cholesterol levels
in bile and decrease gallbladder movement, both of which can lead to
- Ethnicity. Native Americans have a genetic predisposition to
secrete high levels of cholesterol in bile. In fact, they have the
highest rates of gallstones in the United States. A majority of Native
American men have gallstones by age 60. Among the Pima Indians of
Arizona, 70 percent of women have gallstones by age 30. Mexican-American
men and women of all ages also have high rates of gallstones.
- Gender. Women between 20 and 60 years of age are twice as
likely to develop gallstones as men.
- Age. People over age 60 are more likely to develop gallstones
than younger people.
- Cholesterol-lowering drugs. Drugs that lower cholesterol
levels in blood actually increase the amount of cholesterol secreted in
bile. This in turn can increase the risk of gallstones.
- Diabetes. People with diabetes generally have high levels of
fatty acids called triglycerides. These fatty acids increase the risk of
- Rapid weight loss. As the body metabolizes fat during rapid
weight loss, it causes the liver to secrete extra cholesterol into bile,
which can cause gallstones.
- Fasting.Fasting decreases gallbladder movement, causing the
bile to become overconcentrated with cholesterol, which can lead to
Dieting and Gallstones: NIDDK (Excerpt)
researchers believe three conditions are necessary to form gallstones.
First, the bile becomes supersaturated with cholesterol, which means the
bile contains more cholesterol than the bile salts can dissolve. Second,
an imbalance of proteins or other substances in the bile causes the
cholesterol to start to crystallize. Third, the gallbladder does not
contract enough to empty its bile regularly.
(Source: excerpt from Dieting and Gallstones: NIDDK)
Medical news summaries relating to Gallstones:
The following medical news items are relevant to causes of Gallstones:
Related information on causes of Gallstones:
As with all medical conditions,
there may be many causal factors.
Further relevant information on causes of Gallstones may be found in:
» Next page: Risk Factors for Gallstones
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