Signs of Holoprosencephaly
Symptoms of Holoprosencephaly
The list of medical symptoms mentioned in various sources
for Holoprosencephaly may include:
List of 20
Note that Holoprosencephaly symptoms usually refers to various medical symptoms known to a patient,
but the phrase Holoprosencephaly signs may often refer to those signs
that are only noticable by a doctor.
Signs or Symptoms of Holoprosencephaly:
the disorder consists of a spectrum of defects or malformations of the
brain and face.
Most cases are associated with severe malformations of the
brain which are incompatible with life and often cause spontaneous
intrauterine death. At the other end of the spectrum are individuals with
facial defects -- which may affect the eyes, nose, and upper lip -- and
normal or near-normal brain development. Seizures and mental retardation
may occur. The most severe of the facial anomalies is cyclopia, an
abnormality characterized by a single eye, located in the area normally
occupied by the root of the nose, and a missing nose or a nose in the form
of a proboscis (a tubular appendage), located above the eye. Ethmocephaly
is the least common facial anomaly. It consists of a proboscis separating
narrow-set eyes with an absent nose and microphthalmia (abnormal smallness
of one or both eyes). Cebocephaly, another facial anomaly, is
characterized by a small, flattened nose with a single nostril situated
below incomplete or underdeveloped closely set eyes. The least severe in
the spectrum of facial anomalies is the median cleft lip also called
(Source: excerpt from NINDS Holoprosencephaly Information Page: NINDS)
More Symptoms of Holoprosencephaly:
More detailed symptom information may be found on the symptoms of Holoprosencephaly article.
In addition to the above medical information, to get a full picture
of the possible signs or symptoms of this condition
and also possibly the signs and symptoms of its related medical conditions,
it may be necessary to examine symptoms
that may be
Medical articles on signs and symptoms:
These general reference articles may be related
to medical signs and symptoms of disease in general:
What are the signs of Holoprosencephaly?
The phrase "signs of Holoprosencephaly" should, strictly speaking,
refer only to those signs and symptoms of Holoprosencephaly that are not readily apparent to the patient.
The word "symptoms of Holoprosencephaly" is the more general meaning; see symptoms of Holoprosencephaly.
The signs and symptom information on this page
attempts to provide a list of some possible signs and symptoms of Holoprosencephaly.
This medical information about signs and symptoms for Holoprosencephaly has been gathered
from various sources,
may not be fully accurate,
and may not be the full list of Holoprosencephaly signs or Holoprosencephaly symptoms.
Furthermore, signs and symptoms of Holoprosencephaly may vary on an individual basis for each patient.
Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they
are indeed Holoprosencephaly symptoms.