Diseases » Hyper-IgM Syndrome » Introduction

Hyper-IgM Syndrome

Hyper-IgM Syndrome: Introduction

Hyper-IgM Syndrome: Immunodeficiency with hyper-IgM (HIM) is a rare primary immunodeficiency characterized by the production of normal to increased amounts of IgM antibody of questionable quality ... more about Hyper-IgM Syndrome.

Hyper-IgM Syndrome: A rare inherited immunodeficiency disorder which causes frequent infections involving the ears, eyes, sinuses, lungs, skin, respiratory tract and other areas of the body. More detailed information about the symptoms, causes, and treatments of Hyper-IgM Syndrome is available below.

Symptoms of Hyper-IgM Syndrome

• Recurring respiratory infections
• Enlarged tonsils
• Enlarged liver
• Enlarged spleen
• Chronic diarrhea
• more symptoms...»

See full list of 17 symptoms of Hyper-IgM Syndrome

Treatments for Hyper-IgM Syndrome

• Intravenous immunogloblulin (IVIG)
• Granulocyte colony-stimulating factor (G-CSF) - for neutropenia
• Antibiotics - for infections or preventive maintenance.
• more treatments...»

Read more about treatments for Hyper-IgM Syndrome

Wrongly Diagnosed with Hyper-IgM Syndrome?

• Misdiagnosis of Hyper-IgM Syndrome
• Failure to diagnose Hyper-IgM Syndrome
• Undiagnosed: Hyper-IgM Syndrome

Hyper-IgM Syndrome: Related Patient Stories

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• i m in major pain..need help
• Mrs.M.
• daily constant headache with increasing blurry vision
• diagnosis of celiac in immunodeficiency
• Increased Hunger and Asthma
• Increasing discomfort

Diagnostic Tests for Hyper-IgM Syndrome

• Immune function blood tests
• IgA levels
• IgG levels
• more tests...»

Read more about tests for Hyper-IgM Syndrome

Hyper-IgM Syndrome: Complications

Review possible medical complications related to Hyper-IgM Syndrome:

• Opportunistic infections
• Pneumocystis carinii pneumonia
• Non-Hodgkins lymphoma - higher risk of NHL.
• Neurological complications
• Lymphoma
• more complications...»

Causes of Hyper-IgM Syndrome

Read more about causes of Hyper-IgM Syndrome.

Disease Topics Related To Hyper-IgM Syndrome

Research the causes of these diseases that are similar to, or related to, Hyper-IgM Syndrome:

• Hypohidrotic ectodermal dysplasia
• Humoral immunity
• Somatic hypermutation
• SHM
• CD40 ligand
• more related diseases...»

Research about Hyper-IgM Syndrome

Visit our research pages for current research about Hyper-IgM Syndrome treatments.

Statistics for Hyper-IgM Syndrome

• Medical statistics for Hyper-IgM Syndrome
• Prevalence and incidence statistics for Hyper-IgM Syndrome
• Death and Mortality statistics for Hyper-IgM Syndrome
• Society statistics for Hyper-IgM Syndrome

Hyper-IgM Syndrome: Broader Related Topics

• Primary Immune Deficiency
• Immune disorders
• Immune deficiency conditions
• Genetic Disease
• more types...»

Types of Hyper-IgM Syndrome

Hyper-IgM Syndrome Message Boards

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User Interactive Forums

Read about other experiences, ask a question about Hyper-IgM Syndrome, or answer someone else's question, on our message boards:

• I can not get a diagnosis. Please help.
• Tell us your medical story.
• Share your misdiagnosis story.
• What is the best treatment for this?
• See all the forums.

Article Excerpts about Hyper-IgM Syndrome

Genes and Disease by the National Center for Biotechnology (Excerpt)

Immunodeficiency with hyper-IgM (HIM) is a rare primary immunodeficiency characterized by the production of normal to increased amounts of IgM antibody of questionable quality and an inability to produce sufficient quantities of IgG and IgA. Individuals with HIM are susceptible to recurrent bacterial infections and are at an increased risk of autoimmune disorders and cancer at an early age. (Source: Genes and Disease by the National Center for Biotechnology)

Primary Immune Deficiency, NIAID Fact Sheet: NIAID (Excerpt)

Hyper-IgM is a rare immunodeficiency disease in which the immune system fails to produce IgA and IgG antibodies. (Source: excerpt from Primary Immune Deficiency, NIAID Fact Sheet: NIAID)

Definitions of Hyper-IgM Syndrome:

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Hyper-IgM Syndrome as a "rare disease".
Source - Orphanet

 » Next page: What is Hyper-IgM Syndrome?

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