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Diseases » Hypothyroidism » Glossary
 

Glossary for Hypothyroidism

  • 17-Beta-hydroxysteroid dehydrogenase III deficiency: A rare disorder characterized caused by an enzyme (17-ketosteroid reductase) defect only in the testes which results in a lack of testosterone which is needed during the fetal stage to give males there physical characteristics.
  • ACTH deficiency, isolated: An inherited deficiency of adrenocorticotropic hormone. The condition results from a genetic defect.
  • ADHD: Attention Deficit Hyperactivity Disorder (ADHD) is a mental and behavioral disorder characterized by behavioral problems such as hyperactivity, inattention, concentration difficulty, and other mental symptoms. Typically, ADHD and associated hyperactivity is known as a childhood disorder, although ADD/ADHD in adults is known to be under-diagnosed. It is distinguished from Attention Deficit Disorder (ADD) which has a reduced focus on hyperactivity type symptoms.
  • APECED Syndrome: APECED is a recessively inherited genetic disease characterized by the presence of two of the following three conditions: impaired parathyroid function, yeast infection (candidiasis) and impaired adrenal gland function (Addison's disease). It is an autoimmune disease resulting from a genetic defect. The body's immune system malfunctions and attacks it's own body tissues.
  • Acanthocytosis: A rare disorder where most of the red blood cells are abnormal with spiny projections due to lipid abnormalities. The blood abnormality is seen in conditions such as abetalipoproteinemia, severe liver disease and severe malnutrition. Symptoms and prognosis depend on the underlying disorder.
  • Acquired hypothyroidism: Acquired hypothyroidism is a condition where the thyroid gland makes too little or no thyroid hormone. Acquired hypothyroidism can be caused by both thyroid disease (primary hypothyroidism) and hypothalamic-pituitary disease (central hypothyroidism)
  • Adrenoleukodystrophy: A rare disorder which has characteristic symptoms of Addison disease (adrenocortical insufficiency) and Schilder disease (cerebral sclerosis). Bronze skin, brain sclerosis and demyelination are the main symptoms.
  • Alopecia: Various types of hair loss or balding
  • Alström Syndrome: A progressive condition which is characterized by deafness, obesity and visual problems in childhood that may lead to diabetes and kidney failure in adulthood
  • Alzheimer's Disease: Dementia-causing brain disease mostly in seniors and the elderly.
  • Amiodarone -- Teratogenic Agent: There is strong evidence to indicate that exposure to Amiodarone during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Amyloidosis: A rare group of metabolic disorders where a protein called amyloid accumulates in body organs and tissues where it can cause damage and is potentially fatal. Symptoms depend on the organs involved. There are numerous forms of the condition: primary amyloidosis, secondary amyloidosis, hemodialysis-associated amyloidosis and familial amyloidosis.
  • Anemia: Reduced ability of blood to carry oxygen from various possible causes.
  • Anovulation: Failure to ovulate
  • Antithyroid drugs -- Teratogenic Agent: There is strong evidence to indicate that the use of Antithyroid drugs during pregnancy may cause a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Ascites: Fluid accumulation in abdominal cavity
  • Autoimmune disorders -- Teratogenic Agent: There is strong evidence to indicate that the development of autoimmune disorders during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the stage of pregnancy that the exposure occurred at.
  • Autoimmune enteropathy, type 1: A rare condition involving autoimmune problems which can variably manifest as enteropathy (diarrhea), hemolytic anemia, and endocrine gland diseases such as diabetes mellitus and thyroid disease. Resistance to viral infections is poor. The condition is life-threatening, especially during infancy and early childhood. As the condition is inherited in a X-linked manner, males tend to suffer severe symptoms whereas females suffer few if any symptoms as they are a carrier of the condition.
  • Autoimmune thyroid diseases: Autoimmune diseases of the thyroid gland.
  • Bamforth syndrome: A rare syndrome characterized mainly by the association of an abnormal opening in the roof of the mouth and reduced thyroid functioning.
  • Bangstad syndrome: A rare disorder characterized by diabetes, goiter, insufficient hormone production by the gonads and progressive ataxia.
  • Bilateral abductor vocal cord paralysis syndrome: A complication that can occur following the removal of the thyroid gland.
  • Bradycardia: Excessively slow heart beat.
  • CATCH 22: A term used to describe a group of disorders resulting from a deletion on chromosome 22q11 and involving heart and face abnormalities, T cell deficit due to an underdeveloped thymus, cleft palate, low blood calcium due to hypothyroidism. This term tends to include disorders such as Shprintzen syndrome, velocardiofacial syndrome, DiGeorge syndrome and Takao syndrome.
  • CDG syndrome type 1A: A very rare inherited metabolic disorder where defective carbohydrate compounds are attached to glycoproteins and thus impairing glycoprotein function. Type 1A involves a phosphomannomutase enzyme defect and affects most body systems especially the nervous system and liver function.
  • Carbimazole -- Teratogenic Agent: There is strong evidence to indicate that exposure to Carbimazole during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Cardiac tamponade: Symptoms caused by compression of the heart due to the accumulation of blood or fluid in the space between the heart muscle and the membrane covering the heart.
  • Cardiovascular Disease: Diseases of the heart or blood vessels including cerebrovascular diseases such as stroke.
  • Carpal Tunnel Syndrome: Hand or wrist problems; often from repetitive motion.
  • Celiac Disease: Digestive intolerance to gluten in the diet.
  • Chemical poisoning -- Bromide: Bromide is a chemical used for many applications - flame retardant, industrial uses, pesticides, sanitary products, fumigants, medicines, dyes, photographic solutions and water purification. Bromides act as central nervous system depressants and the ingestion of excessive quantities can cause serious symptoms. Ingestion and other exposures to the chemical can cause various symptoms. The type and severity of symptoms varies depending on the amount of chemical involved and the nature of the exposure.
  • Chromosome 1, 1p36 deletion syndrome: A rare chromosomal disorder where deletion of a portion of chromosome 1 causes various abnormalities such as heart problems, mental retardation, developmental delay, facial dysmorphism and short stature. The symptoms are variable depending on the exact location of chromosomal deletion.
  • Chromosome 10, Monosomy 10p:
  • Chromosome 10p deletion syndrome: A rare chromosomal disorder where there is a deletion of the short arm (p) of chromosome 10 resulting in variable abnormalities.
  • Chromosome 12 ring syndrome: A rare chromosomal disorder where genetic material from one or both ends of chromosome 12 is missing and the two broken ends have rejoined to form a ring. The resulting type and severity of symptoms is determined by the amount and location of genetic material missing.
  • Chromosome 15q duplication syndrome: A rare chromosomal disorder involving an extra copy of genetic material from the long arm of chromosome 15. The type and severity of symptoms are determined by the amount and location of the duplicated genetic material.
  • Chromosome 15q, trisomy: A rare chromosomal disorder involving an extra copy of genetic material from the long arm of chromosome 15. The type and severity of symptoms are determined by the amount and location of the duplicated genetic material.
  • Chromosome 2 trisomy syndrome: A rare chromosomal disorder where there are three copies of chromosome 2 instead of the normal two.
  • Chromosome 6, trisomy 6q: A rare chromosomal disorder involving duplication of the long arm (q) of chromosome 6 which results in various abnormalities depending on the size and location of the portion of duplicated genetic material.
  • Chromosome 6q duplication syndrome: A rare chromosomal disorder involving duplication of the long arm (q) of chromosome 6 which results in various abnormalities depending on the size and location of the portion of duplicated genetic material.
  • Chronic Fatigue Syndrome: Severe chronic fatigue disorder often following infection.
  • Chronic infections: Ongoing and often slow progressing infection; opposite to acute infections.
  • Cold sensitivity: Feeling cold or sensitivity to the cold
  • Congenital Disorders of Glycosylation Type Ia: A very rare inherited metabolic disorder where defective carbohydrate compounds are attached to glycoproteins and thus impairing glycoprotein function. Type 1A involves a phosphomannomutase enzyme defect and affects most body systems especially the nervous system and liver function.
  • Congenital disorder of glycosylation type 1A: A very rare inherited metabolic disorder where defective carbohydrate compounds are attached to glycoproteins and thus impairing glycoprotein function. Type 1A involves a phosphomannomutase enzyme defect and affects most body systems especially the nervous system and liver function.
  • Congenital disorder of glycosylation type 1H: Congenital disorders of glycosylation is a group of very rare inherited metabolic disorder where defective carbohydrate compounds are attached to glycoproteins and thus impairing glycoprotein function. Type Ih is caused by a defect on chromosome 11pter-p15.5 and involves the gene for a particular enzyme (dolichyl-P-glucose:Glc-1-Man-9-GlcNAc-2-PP-dolichyl-alpha-3-glucosyltransferase).
  • Congenital hypothyroidism: A condition in infancy or early childhood due to an in-utero deficiency of thyroid hormones that can be caused by genetic or environmental factors, such as thyroid dysgenesis or hypothyroidism in infants of mothers treated with thiouracil during pregnancy.
  • Congestive Heart Failure: Inadequate pumping and decline of heart function common in the elderly.
  • Constipation: Difficult or dry bowel movements
  • Cretinism athyreotic: A rare form of congenital hypothyroidism that causes mental and physical growth retardation in infants or children. Prompt thyroid hormone therapy is essential in order to prevent progressive neurological and motor deterioration.
  • Cystic Fibrosis: Cystic fibrosis is a hereditary disease affecting the exocrine (mucus) glands of the lungs, liver, pancreas, and intestines, causing progressive disability due to multisystem failure.
  • Cystinosis: A rare biochemical disorder involving the accumulation of a chemical called cystine in various parts of the body which can cause harmful effects.
  • Deafness -- goiter -- stippled epiphyses: A congenital metabolic disorder where the body fails to respond to thyroid hormone even though there is sufficient quantities of the hormone.
  • Deafness -- thyroid hormone resistance: An inherited disorder where the body fails to respond to thyroid hormone even though there is sufficient quantities of the hormone.
  • Del (2) (q22-q23): A rare chromosomal disorder characterized by various anomalies. The listed symptoms are those observed in one reported case. The manifestations linked to most genetic defects are often variable to some degree.
  • Del (3) (pter-p25.1): A rare chromosomal disorder characterized by various anomalies. The listed symptoms are those observed in one reported case. The manifestations linked to most genetic defects are often variable to some degree.
  • Delirium: Severe state of mental confusion
  • Dementia: Various mental impairment conditions.
  • Depression: Various syndromes with excessive anxiety, phobias, or fear.
  • DiGeorge's syndrome: Rare form of primary immune deficiency
  • Diabetes: Failing or reduced ability of the body to handle sugars.
  • Diabetes insipidus, diabetes mellitus, optic atrophy: A rare association of diabetes insipidus, diabetes mellitus, optic atrophy, and deafness.
  • Diabetes mellitus, congenital insulin-dependent, with fatal secretory diarrhea: A rare condition involving autoimmune problems which can variably manifest as enteropathy (diarrhea), hemolytic anemia, and endocrine gland diseases such as diabetes mellitus and thyroid disease. Resistance to viral infections is poor. The condition is life-threatening, especially during infancy and early childhood. As the condition is inherited in a X-linked manner, males tend to suffer severe symptoms whereas females suffer few if any symptoms as they are a carrier of the condition.
  • Diabetic Gastroparesis: Gastroparesis is a diabetic complication that occurs from neuropathy of the stomach nerve (called the "vagus nerve"). This causes digestive difficulties as the food starts to move too slowly through the stomach.
  • Diarrhea -- polyendocrinopathy -- infections, X-linked: A rare X-linked disorder characterized by diarrhea and severe, fatal infections during infancy. The body's immune system attacks it's own endocrine glands and various other organs. Females are carriers and can have mild symptoms whereas males suffer the fatal course of the disease.
  • Diarrhea, polyendocrinopathy, fatal infection syndrome, X-linked: A rare condition involving autoimmune problems which can variably manifest as enteropathy (diarrhea), hemolytic anemia, and endocrine gland diseases such as diabetes mellitus and thyroid disease. Resistance to viral infections is poor. The condition is life-threatening, especially during infancy and early childhood. As the condition is inherited in a X-linked manner, males tend to suffer severe symptoms whereas females suffer few if any symptoms as they are a carrier of the condition.
  • Distinctive Craniofacial Features -- Pterygia -- Mental Retardation: A very rare syndrome characterized mainly by short stature, underdeveloped genitals and various skull and facial anomalies.
  • Down Syndrome: A chromosome syndrome causing physical effects and mental retardation.
  • Dry hair: A condition which is characterized by a dry texture to ones hair
  • Dup (2) (q11.2-q21.1): A rare chromosomal disorder characterized by various anomalies. The listed symptoms are those observed in two reported cases. The manifestations linked to most genetic defects are often variable to some degree.
  • Duplication 6q: A rare chromosomal disorder involving duplication of the long arm (q) of chromosome 6 which results in various abnormalities depending on the size and location of the portion of duplicated genetic material.
  • Dysmenorrhea: Pain, cramping, or discomfort due to menstruation
  • Emanuel syndrome: A rare chromosomal disorder where a portion of chromosome 11 is translocated with a portion of chromosome 22. The disorder involves a wide range of abnormalities such as kidney, genital and heart abnormalities, mental retardation, small head and failure to thrive.
  • Emotional stress: A condition which occurs when a person is under stress affecting their emotions
  • Empty Sella Syndrome: Congenital defect of the brain.
  • Endocrine disorders: Any disorder that affects the endocrine system
  • Endocrine system conditions: Medical conditions affecting the endocrine systems, such as the related hormones or glands.
  • Enteropathy, autoimmune, with hemolytic anemia and polyendocrinopathy: A rare condition involving autoimmune problems which can variably manifest as enteropathy (diarrhea), hemolytic anemia, and endocrine gland diseases such as diabetes mellitus and thyroid disease. Resistance to viral infections is poor. The condition is life-threatening, especially during infancy and early childhood. As the condition is inherited in a X-linked manner, males tend to suffer severe symptoms whereas females suffer few if any symptoms as they are a carrier of the condition.
  • Erythema ab igne:
  • Escamilla-Lisser syndrome: Hypothyroidism in adults where external signs may be few or absent but serious problems can occur internally. Some of the problems includes weakened muscles in the heart, intestines and bladder.
  • Fatigue: Excessive tiredness or weakness.
  • Female infertility: Infertility that affects the female
  • Fibromyalgia: A difficult to diagnose condition affecting the muscles and/or joints
  • Forgetfulness: Forgetting things or loss of memory ability
  • Galactorrhoea-Hyperprolactinaemia: Increased blood prolactin levels associated with galactorrhea (abnormal milk secretion). It may be caused by such things as certain medications, pituitary disorders and thyroid disorders. The condition can occur in males as well as females.
  • Generalized resistance to thyroid hormone: An inherited disorder where the body fails to respond to thyroid hormone even though there is sufficient quantities of the hormone.
  • Graves Disease: is an autoimmune disease characterized by hyperthyroidism due to circulating autoantibodies. Thyroid-stimulating immunoglobulins (TSIs) bind to and activate thyrotropin receptors, causing the thyroid gland to grow and the thyroid follicles to increase synthesis of thyroid hormone.
  • Hair loss: Loss or thinning of head or body hair
  • Hashimoto's Thyroiditis: Hashimoto thyroiditis is characterized by the destruction of thyroid cells by various cell- and antibody-mediated immune processes. Patients with Hashimoto thyroiditis have antibodies to various thyroid antigens, the most frequently detected of which include antithyroid peroxidase (anti-TPO), antithyroglobulin (anti-Tg), and, to a lesser extent, TSH receptor-blocking antibodies.
  • Haspeslagh Fryns Muelenaere syndrome: A very rare syndrome characterized mainly by short stature, underdeveloped genitals and various skull and facial anomalies.
  • Hemochromatosis: Excess of iron leading to problems with joints, liver, heart and pancreas.
  • Hemochromatosis-related diabetes: A single-gene disease that causes iron accumulation in the tissues of the body. Diabetes is a primary complication if hemochromatosis goes untreated. Hemochromatosis is sometimes referred to as "bronze diabetes."
  • Hereditary hypothyroidism: Hereditary hypothyroidism is a condition in which there is a defect in the thyroid gland which leads to increased production of TSH reduced production of thyroid hormone.
  • High Cholesterol: High levels of blood cholesterol, triglycerides, or other lipids.
  • Hirsutism: Increased hairiness
  • Hoarse: Hoarseness or loss of voice
  • Hoarseness: Reduction or loss of voice
  • Hyperpigmentation: Excess skin pigment or coloration
  • Hyperprolactinemia: High levels of prolactin in the blood.
  • Hypersomnia: Hypersomnia is characterized by recurring episodes of excessive daytime sleepiness (EDS) or prolonged nighttime sleep.
  • Hyperthyroidism: Too much thyroid hormone production.
  • Hypoadrenocorticism -- hypoparathyroidism -- moniliasis: An autoimmune disorder where hormone production by various glands is reduced. The main features of the disorder are Addison disease and/or hypoparathyroidism and/or chronic candidiasis.
  • Hypoalbuminemia: Low levels of albumin (protein) in the blood.
  • Hypochondriasis: A disorder characterised by a preoccupation with normal bodily functions as abnormalities
  • Hypomelia -- mullerian duct anomalies: A rare genetic disorder characterized by severely underdeveloped arms and uterine and vaginal abnormalities.
  • Hypopituitarism: A disorder caused by reduced pituitary hormone levels. Hormones produce by the pituitary gland produces growth hormones, prolactin, thyroid stimulating hormone, antidiuretic hormone and others.
  • Hypothalamic dysfunction: Abnormal function of the thalamus located in the brain. The thalamus controls pituitary gland function which in turn controls other hormone producing glands such as the thyroid gland, adrenal gland, ovaries and testes. The thalamus also regulates functions such as temperature control, emotions, sleep, appetite and salt balance. Abnormal thalamus functioning may be caused by such things as surgery, infection, genetic disorders, poor nutrition and tumors.
  • Hypothermia: Low body temperature
  • Hypothyroidism: Too little thyroid hormone production.
  • Hypothyroidism -- cleft palate: A rare syndrome characterized mainly by the association of an abnormal opening in the roof of the mouth and reduced thyroid functioning.
  • Hypothyroidism -- dermoid cyst -- cleft palate: A rare syndrome characterized by primary hypothyroidism, dermoid cyst, cleft palate and other abnormalities.
  • Hypothyroidism postaxial polydactyly mental retardation: A very rare syndrome characterized by abnormally low thyroid levels, extra digits, mental retardation and unusually facial appearance.
  • IPEX syndrome: A rare condition involving autoimmune problems which can variably manifest as enteropathy (diarrhea), hemolytic anemia, and endocrine gland diseases such as diabetes mellitus and thyroid disease. Resistance to viral infections is poor. The condition is life-threatening, especially during infancy and early childhood. As the condition is inherited in a X-linked manner, males tend to suffer severe symptoms whereas females suffer few if any symptoms as they are a carrier of the condition.
  • Immune dysregulation -- polyendocrinopathy -- enteropathy, X linked: A rare condition involving autoimmune problems which can variably manifest as enteropathy (diarrhea), hemolytic anemia, and endocrine gland diseases such as diabetes mellitus and thyroid disease. Resistance to viral infections is poor. The condition is life-threatening, especially during infancy and early childhood. As the condition is inherited in a X-linked manner, males tend to suffer severe symptoms whereas females suffer few if any symptoms as they are a carrier of the condition.
  • Impotence: Inability to attain or sustain an erection.
  • Inborn errors of thyroid hormone synthesis related to hypothyroidism: Congenital hypothyroidism is inadequate thyroid hormone production in newborn infants. This can occur because of an anatomic defect in the gland, an inborn error of thyroid metabolism, or iodine deficiency.
  • Infantile hypothyroidism: A condition in infancy or early childhood due to an in-utero deficiency of thyroid hormones that can be caused by genetic or environmental factors, such as thyroid dysgenesis or hypothyroidism in infants of mothers treated with thiouracil during pregnancy.
  • Infertility: The inability to produce offspring
  • Iodine -- Teratogenic Agent: There is evidence to indicate that exposure to Iodine during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Iodine antenatal infection: Excessive fetal exposure to iodine which can destroy part or all of the thyroid gland.
  • Iodine deficiency: Dietary deficiency of iodine affecting the thyroid.
  • Irritable bowel syndrome: Spasms in the colon wall
  • Itching: Itching feeling of the skin.
  • Johanson-Blizzard Syndrome: A rare genetic disorder involving a range of abnormalities including a characteristic beak-like small nose, hypothyroidism and deafness.
  • Kaplowitz-Bodurtha syndrome: A very rare syndrome characterized mainly by reduced pituitary hormone production and small eyes.
  • Kashin-Bek disease: A disease involving progressive joint degeneration which affects the spine and hands and feet. The condition becomes progressively worse and eventually leads to disability. The condition is most often seen in children who live in the northern parts of China, Siberia and Korea. A possible cause is believed to be eating cereals contaminated with a fungus called Sporotrichella.
  • Langerhans Cell Histiocytosis: A condition which is characterized by proliferation of Langerhans cells
  • Lethargy: feeling of tiredness
  • Lithium -- Teratogenic Agent: There is evidence to indicate that exposure to Lithium during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Lymphomatous thyroiditis: Progressive thyroid gland enlargement due to autoimmune disease.
  • Macroglossia: Abnormally large tongue.
  • Menopause: The end of female menstruation and fertility.
  • Menorrhagia: Excessive menstrual bleeding
  • Mental Retardation -- Pterygia -- Shortness -- Distinctive Facial Appearance: A very rare syndrome characterized mainly by short stature, underdeveloped genitals and various skull and facial anomalies.
  • Mental mixed retardation deafnes clubbed digits: A rare disorder characterized mainly by mental retardation, deafness and clubbed fingers.
  • Metabolic disorders: Disorders that affect the metabolic system in human
  • Methimazole -- Teratogenic Agent: There is evidence to indicate that exposure to Methimazole during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Microcephaly -- seizures -- mental retardation -- heart disorders: A very rare syndrome characterized mainly by a small head, seizures, mental retardation and heart disorders.
  • Microphthalmia syndromic, type 6: A rare inherited syndrome characterized mainly by small eyes, malformed ears, small jaw and finger and genital abnormalities. The symptoms are variable to some degree.
  • Mononucleosis: Common infectious virus.
  • Monosomy 1p36: A rare chromosomal disorder where deletion of a portion of chromosome 1 causes various abnormalities such as heart problems, mental retardation, developmental delay, facial dysmorphism and short stature. The range and severity of symptoms is variable with some cases being relatively mild.
  • Multiple endocrine abnormalities -- adenylyl cyclase dysfunction: A rare syndrome characterized by an enzyme defect (adenylyl cyclase) and a number of endocrine abnormalities.
  • Muscle cramps: A condition which is characterized by the uncontrolled contractions of muscles
  • Muscular Hypertrophy: An increase in the size of the muscle cells.
  • Myopathy: General name for any disease of the muscles.
  • Myositis: One of the underlying causes for muscle weakness/myopathy.
  • Myxedema: Skin and tissue disorder usually due to hypothyroidism
  • Myxedema coma: Myxedema coma is a rare, life-threatening condition, occurs late in the progression of hypothyroidism. The condition is seen typically in elderly women and is often precipitated by infection, medication, environmental exposure, or other metabolic-related stresses.
  • Nephrotic syndrome: Various kidney glomeruli conditions
  • Neurosarcoidosis: A rare disorder involving sarcoidosis of the nervous system. Sarcoidosis is a chronic inflammatory disorder that can affect virtually any part of the body. Neurosarcoidosis involves inflammation and abnormal deposits in parts of the nervous system including the brain and spinal cord which affects their functioning. Symptoms may be sudden and severe or may be mild and progress slowly. Symptoms are determined by the degree of nerve involvement.
  • Obesity: An increase in the body weight greater than that required for normal function that is characterised by the accumulation of excessive fat
  • Obesity -- colitis -- hypothyroidism -- cardiac hypertrophy -- developmental delay: A rare syndrome characterized by obesity, colitis, hypothyroidism, enlarged heart and developmental delay. The two reported cases involved maternal HELLP syndrome during pregnancy. Both infants died within months of birth.
  • Obstructive sleep apnea: Obstructive sleep apnea (OSA) syndrome is characterized by episodic upper airway obstruction that occurs during sleep.
  • Oligomenorrhea: A medical term that refers to light or infrequent menstrual periods. The condition can be caused by a number of disorders including Graves disease, thyrotoxicosis or a pituitary tumor.
  • POEMS syndrome: A very rare disorder that has widespread effects on the body: P - polyneuropathy, O - organopathy, E - endocrinopathy, M - monoclonal gammopathy, S - skin changes.
  • Para-Amino Salicylic Acid -- Teratogenic Agent: There is evidence to indicate that exposure to Para-Amino Salicylic Acid during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Pendred syndrome: An inherited condition characterized by hearing loss and goiter formation. The enlarged thyroid gland often continuges to function normally.
  • Pericardial effusion: Occurs when there is an abnormal collection of fluid within the pericardial sac
  • Pericarditis: Inflammation of the membrane surrounding the heart
  • Pituitary Cancer: Cancer of the pituitary gland.
  • Polycystic ovary syndrome: Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects approximately 5% of all women.
  • Polyendocrine deficiency syndrome type 2: Multi-endocrine syndrome usually affecting young adults.
  • Polyendocrinopathy, immune dysfunction, and diarrhea, X-linked: A rare condition involving autoimmune problems which can variably manifest as enteropathy (diarrhea), hemolytic anemia, and endocrine gland diseases such as diabetes mellitus and thyroid disease. Resistance to viral infections is poor. The condition is life-threatening, especially during infancy and early childhood. As the condition is inherited in a X-linked manner, males tend to suffer severe symptoms whereas females suffer few if any symptoms as they are a carrier of the condition.
  • Polyglandular Autoimmune Syndrome: A group of rare genetic disorders characterized by the malfunction of more than one endocrine gland resulting in impaired hormone production. The gland malfunction results from autoimmune damage to the tissue. There are four subtypes of the disorder.
  • Possible human carcinogenic exposure -- Propylthiouracil: Some evidence indicates that exposure to Propylthiouracil has a possible link to an increased risk of developing cancer in humans. The carcinogenicity of the substance may be influenced by the duration and level of exposure. Propylthiouracil is a pharmaceutical drug used to treat hyperthyroidism.
  • Postpartum hypothyroidism: Postpartum hypothyroidism is a relatively common disorder that has previously been unrecognized and untreated. Although symptoms are temporary and usually mild, most women are relieved to learn that their symptoms are not all in their heads, that they are not "losing their minds," that they don't have a life-threatening disease, and that there are inexpensive, effective treatments to relieve their discomfort.
  • Postpartum thyroiditis: A condition which is characterized by inflammation of the thyroid after a pregnancy
  • Potassium Iodide -- Teratogenic Agent: There is evidence to indicate that exposure to Potassium Iodide during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Premenstrual syndrome: Condition with cyclic symptoms related to menstruation.
  • Primary hypothyroidism: Primary hypothyroidism is a condition in which a defect in the thyroid gland leads to reduced production of thyroid hormone.
  • Prolactinoma: Benign cancer of the pituitary gland producing prolactin.
  • Proximal muscle weakness: Weakness of the proximal muscles
  • Pterygia -- Mental retardation -- Distinctive Craniofacial Features: A very rare syndrome characterized mainly by short stature, underdeveloped genitals and various skull and facial anomalies.
  • Retinohepatoendocrinologic syndrome: A rare inherited disorder characterized mainly by eye, liver and endocrine function abnormalities.
  • Riedel syndrome: A rare condition that occurs when fibrous tissue forms in the thyroid area and progressively destroys the thyroid gland.
  • Sarcoidosis: Rare autoimmune disease usually affecting the lungs.
  • Short stature -- craniofacial anomalies -- genital hypoplasia: A very rare syndrome characterized mainly by short stature, underdeveloped genitals and various skull and facial anomalies.
  • Sinus bradycardia: A condition which is characterized by a slow heart rate
  • Sleep apnea: Childhood obstructive sleep apnea (OSA) syndrome is characterized by episodic upper airway obstruction that occurs during sleep.
  • Sleep disorders: Any disorder that affects ones sleep
  • Slow relaxing reflexes: The occurrence of reflexes that are slow and relaxing
  • Speech symptoms: Problems with speech or voice.
  • Stress: Emotional stress (sometimes refers to physical stress)
  • Sub clinical hypothyroidism: Sub clinical hypothyroidism, also referred to as mild hypothyroidism, is defined as normal serum free T4 levels with slightly high serum TSH concentration.
  • Subacute granulomatous thyroiditis: Subacute thyroiditis is a self-limited thyroid condition associated with a triphasic clinical course of hyperthyroidism, hypothyroidism, and return to normal thyroid function.
  • Thyroid disorders: Any disorder of the thyroid gland.
  • Thyroid symptoms: Symptoms affecting the thyroid gland
  • Thyroiditis: Thyroid gland inflammation
  • Tiredness: Feeling tired either physically or mentally
  • Under-diagnosed conditions: Any medical condition that is undiagnosed
  • Vague symptoms: Vague, unclear, mild or non-specific symptoms
  • Velocardiofacial syndrome: A genetic disorder which can present with a wide range of phenotypic manifestations which has lead to a number of different names being assigned to the various presentations e.g. DiGeorge Syndrome and Cayler Anomaly Face Syndrome. There are nearly 200 different symptoms that can occur and the severity of the condition is also highly variable depending on the nature and severity of the symptoms that are present.
  • Vilanova-Canadeli syndrome: A syndrome involving the association of hypothyroidism and a skin disorder caused by vitamin A deficiency.
  • Weight Gain: An increase in weight for any reason.
  • Wolfram Syndrome 2: Wolfram Syndrome is a condition characterized by the association of diabetes insipidus, diabetes mellitus, optic atrophy and deafness. Type 2 is the result of a genetic defect and is similar to type 1 but there is no diabetes insipidus and patients tend to develop gastrointestinal problems.
  • Womens health conditions: Medical conditions related to women's health.
  • Zadik Barak Levin syndrome: A condition that affects the endocrine system as well as some facial characteristics

 

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