Japanese encephalitis: A form of encephalitis caused by a flavivirus (Japanese B encephalitis virus - JBEV) and transmitted by mosquito bites. Most cases are mild and asymptomatic but severe cases can lead to death. More detailed information about the symptoms, causes, and treatments of Japanese encephalitis is available below.
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The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.
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A mosquito-borne encephalitis caused by the Japanese B encephalitis virus (ENCEPHALITIS VIRUS, JAPANESE) occurring throughout Eastern Asia and Australia. The majority of infections occur in children and are subclinical or have features limited to transient fever and gastrointestinal symptoms. Inflammation of the brain, spinal cord, and meninges may occur and lead to transient or permanent neurologic deficits (including a POLIOMYELITIS-like presentation); SEIZURES; COMA; and death. (From Adams et al., Principles of Neurology, 6th ed, p751; Lancet 1998 Apr 11;351(9109):1094-7) - (Source - Diseases Database)
Japanese encephalitis is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Japanese encephalitis, or a subtype of Japanese encephalitis,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
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