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Treatments for Kidney damage -- Ethylene glycol ethers

Treatment List for Kidney damage -- Ethylene glycol ethers

The list of treatments mentioned in various sources for Kidney damage -- Ethylene glycol ethers includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.

  • Removal of toxin from body, monitoring and support of kidney function, dialysis if needed, kidney transplant in severe cases
  • Treatment of kidney damage from ingestion of ethylene glycol is dependant upon the severity of damage and the degree of spontaneous recovery, as well as the patients' age, pre-existing renal function and coexisting health problems. Treatments include:
    • Removal from further exposure to the causative agent
    • Supportive therapy in the acute phase
      • Admission to a critical care facility
      • Blocking of alcohol dehydrogenase with ethanol or fomepizole
      • Sodium bicarbonate for treatment of acidosis
      • Thiamine and pyridoxine intravenously
      • Fluid and electrolyte management
      • Dialysis for acute severe renal failure, severe acidosis, and large ingestions
    • Longer term management:
      • Monitoring of renal function to ascertain degree of spontaneous recovery
      • Avoidance of medications that may contribute to further renal damage - NSAID's, IV contrast
      • Smoking cessation - people who continue to smoke increase their risk of progression to end stage renal failure
      • Close management of high blood pressure - ACE (Angiotensin converting enzyme) inhibitors and ARB's (Angiotensin II receptor blockers) usually first line
    • Dietary management
      • Protein management dependant upon urinary protein loss and degree of renal impairment. Protein intake needs to be adequate to avoid malnutrition
      • Sodium management as required. May need to be restricted, or supplemented if salt wasting occurs
      • Adequate hydration
      • Phosphate restriction in chronic renal failure
      • Potassium restriction as necessary
    • Management of chronic renal failure:
      • Erythropoietin agonists - for management of anaemia associated with chronic renal failure
      • Phosphate binders - for management of hyperphosphatemia in chronic renal failure
      • Calcium supplements - for hypocalcaemia
      • Calcitriol and other Vitamin D supplements - for hypocalcaemia and hyperparathyroidism associated with chronic renal failure
      • Sodium bicarbonate - for acid-base disturbance
      • Diuretics - may be used in situation of volume overload
      • Renal dialysis - used when there are manifestations of uraemia and the GFR is < 10mL/min
      • Renal transplantation

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