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Kleiner-Holmes syndrome: A very rare syndrome characterized mainly by big toe abnormalities including partial or complete duplication of the big toe. More detailed information about the symptoms, causes, and treatments of Kleiner-Holmes syndrome is available below.
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Kleiner-Holmes syndrome is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that Kleiner-Holmes syndrome, or a subtype of Kleiner-Holmes syndrome,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
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