LEOPARD Syndrome: A rare genetic disorder characterized by multiple lentigines, pulmonic stenosis, widely spaced eyes and deafness. More detailed information about the symptoms, causes, and treatments of LEOPARD Syndrome is available below.
See full list of 12 symptoms of LEOPARD Syndrome
Home medical testing related to LEOPARD Syndrome:
Read more about complications of LEOPARD Syndrome.
Read more about causes of LEOPARD Syndrome.
Research the causes of these diseases that are similar to, or related to, LEOPARD Syndrome:
See full list of 13 occasional symptoms of LEOPARD Syndrome
Commonly undiagnosed diseases in related medical categories:
Heart attacks can be undiagnosed: Although the most severe symptoms of heart attack are hard to miss, there are varying degrees of severity. It is altogether too common for people to die from undiagnosed heart...read more »
Heart attacks can be overdiagnosed: Although many people die from heart attacks, there are also many cases where people fear that they have a heart attack...read more »
Rare heart condition often undiagnosed: The rare heart condition called long QT syndrome can lead to episodes of palpitations and rapid heartbeat. In rare...read more »
Heart attack can be over-diagnosed: Although heart attack is often undiagnosed, leading to fatality, it can also be over-diagnosed. People become concerned that a condition is a heart attack, whereas...read more »
Blood pressure cuffs misdiagnose hypertension in children: One known misdiagnosis issue with hyperension, arises in relation to the simple equipment used to test blood pressure. The "cuff" around...read more »
Psoriasis often undiagnosed cause of skin symptoms in children: Children who suffer from the skin disorder called psoriasis can often go undiagnosed. The main problem is that psoriasis is rare...read more »
Hypertension misdiagnosis common in children: Hypertension is often misdiagnosed in adults (see misdiagnosis of hypertension), but its misdiagnosis is even more likely in children...read more »
Read more about Misdiagnosis and LEOPARD Syndrome
Research related physicians and medical specialists:
Other doctor, physician and specialist research services:
Research quality ratings and patient safety measures for medical facilities in specialties related to LEOPARD Syndrome:
Hospital & Clinic quality ratings »
Choosing the Best Hospital: More general information, not necessarily in relation to LEOPARD Syndrome, on hospital performance and surgical care quality:
Rare types of diseases and disorders in related medical categories:
Medical research articles related to LEOPARD Syndrome include:
Click here to find more evidence-based articles on the TRIP Database
More LEOPARD Syndrome animations & videos
Visit our research pages for current research about LEOPARD Syndrome treatments.
Read about other experiences, ask a question about LEOPARD Syndrome, or answer someone else's question, on our message boards:
A syndrome characterized by Lentigines (LENTIGO); Electrocardiographic conduction abnormalities; Ocular HYPERTELORISM; PULMONARY STENOSIS; Abnormal genitalia; Retardation of growth; and Deafness (HEARING LOSS, SENSORINEURAL). It is caused by mutations of the PTPN11 gene which codes for non-receptor PROTEIN TYROSINE PHOSPHATASE, type 11. The clinical features of LEOPARD syndrome overlap those of NOONAN SYNDROME, also caused by mutations in PTPN11, as well as those of NEUROFIBROMATOSIS 1. The syndrome has also been associated with mutations in the NF1 gene (GENES, NEUROFIBROMATOSIS 1). (J Med Genet 2002 Aug;39(8):571-4) - (Source - Diseases Database)
LEOPARD Syndrome is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that LEOPARD Syndrome, or a subtype of LEOPARD Syndrome,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
Ophanet, a consortium of European partners,
currently defines a condition rare when it affects 1 person per 2,000.
They list LEOPARD Syndrome as a "rare disease".
Source - Orphanet
Tools & Services:
Medical Articles:
Search Specialists by State and City
By using this site you agree to our Terms of Use. Information provided on this site is for informational purposes only; it is not intended as a substitute for advice from your own medical team. The information on this site is not to be used for diagnosing or treating any health concerns you may have - please contact your physician or health care professional for all your medical needs. Please see our Terms of Use.
Copyright © 2011 Health Grades Inc. All rights reserved. Last Update: 7 May, 2013 (2:14)
