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Letterer-Siwe disease

Letterer-Siwe disease: Introduction

Letterer-Siwe disease: A rare usually fatal condition characterized by skin lesions, bleeding tendency, enlarged liver and spleen, enlarged lymph nodes and progressive anemia. The condition is caused by excessive proliferation of histiocytes. More detailed information about the symptoms, causes, and treatments of Letterer-Siwe disease is available below.

Symptoms of Letterer-Siwe disease

Home Diagnostic Testing

Home medical testing related to Letterer-Siwe disease:

Wrongly Diagnosed with Letterer-Siwe disease?

Letterer-Siwe disease: Related Patient Stories

Letterer-Siwe disease: Deaths

Read more about Deaths and Letterer-Siwe disease.

Letterer-Siwe disease: Complications

Review possible medical complications related to Letterer-Siwe disease:

Causes of Letterer-Siwe disease

Read more about causes of Letterer-Siwe disease.

Disease Topics Related To Letterer-Siwe disease

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Misdiagnosis and Letterer-Siwe disease

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Letterer-Siwe disease: Research Doctors & Specialists

Research related physicians and medical specialists:

Other doctor, physician and specialist research services:

Evidence Based Medicine Research for Letterer-Siwe disease

Medical research articles related to Letterer-Siwe disease include:

Click here to find more evidence-based articles on the TRIP Database

Letterer-Siwe disease: Animations

Research about Letterer-Siwe disease

Visit our research pages for current research about Letterer-Siwe disease treatments.

Clinical Trials for Letterer-Siwe disease

The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.

Some of the clinical trials listed on ClinicalTrials.gov for Letterer-Siwe disease include:

Statistics for Letterer-Siwe disease

Letterer-Siwe disease: Broader Related Topics

User Interactive Forums

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Definitions of Letterer-Siwe disease:

A clinical variant of Langerhans cell histiocytosis characterised by unifocal involvement of a bone (most often), skin, or lung. Patients are usually older children or adults usually presenting with a lytic bone lesion. The etiology is unknown. Morphologically, eosinophilic granuloma is characterised by the presence of Langerhans cells in a characteristic milieu which includes histiocytes, eosinophiles neutrophiles, and small, mature lymphocytes. -- 2003 - (Source - Diseases Database)

Letterer-Siwe disease is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Letterer-Siwe disease, or a subtype of Letterer-Siwe disease, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

 

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