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What is Leukemia, Myeloid, Philadelphia-Negative?

What is Leukemia, Myeloid, Philadelphia-Negative?

  • Leukemia, Myeloid, Philadelphia-Negative: Acute lymphocytic leukemia is a relatively aggressive cancer of the white blood cells. Precursors to white blood cells are called blasts and are made by the bone marrow but in ALL the blasts are abnormal and do not develop into lymphocytes. Instead, the abnormal blasts or leukemic cells multiply rapidly and reduce the level of other types of blood cells such as red blood cells and platelets. The Philadelphia negative form of the condition is not associated with a genetic mutation. It is distinguished from the positive form by the clinical course which is initially the same but progresses to eventual bone marrow failure without a distinct increase in blast cells. Other differences include poor response to chemotherapy, lower white blood cell counts, greater monocytosis, less basophilia, lower bone marrow myeloid to erythroid ratio and increased likelihood of developing thrombocytopenia. Philadelphia negative patients also tend to be older and median survival rates tend to be poorer.

Leukemia, Myeloid, Philadelphia-Negative: Introduction

Types of Leukemia, Myeloid, Philadelphia-Negative:

Broader types of Leukemia, Myeloid, Philadelphia-Negative:

How serious is Leukemia, Myeloid, Philadelphia-Negative?

Complications of Leukemia, Myeloid, Philadelphia-Negative: see complications of Leukemia, Myeloid, Philadelphia-Negative

What causes Leukemia, Myeloid, Philadelphia-Negative?

Causes of Leukemia, Myeloid, Philadelphia-Negative: see causes of Leukemia, Myeloid, Philadelphia-Negative

What are the symptoms of Leukemia, Myeloid, Philadelphia-Negative?

Symptoms of Leukemia, Myeloid, Philadelphia-Negative: see symptoms of Leukemia, Myeloid, Philadelphia-Negative

Complications of Leukemia, Myeloid, Philadelphia-Negative: see complications of Leukemia, Myeloid, Philadelphia-Negative

Leukemia, Myeloid, Philadelphia-Negative: Testing

Diagnostic testing: see tests for Leukemia, Myeloid, Philadelphia-Negative.

Misdiagnosis: see misdiagnosis and Leukemia, Myeloid, Philadelphia-Negative.

How is it treated?

Doctors and Medical Specialists for Leukemia, Myeloid, Philadelphia-Negative: Hematologist ; see also doctors and medical specialists for Leukemia, Myeloid, Philadelphia-Negative.
Treatments for Leukemia, Myeloid, Philadelphia-Negative: see treatments for Leukemia, Myeloid, Philadelphia-Negative
Research for Leukemia, Myeloid, Philadelphia-Negative: see research for Leukemia, Myeloid, Philadelphia-Negative

Name and Aliases of Leukemia, Myeloid, Philadelphia-Negative

Main name of condition: Leukemia, Myeloid, Philadelphia-Negative

Other names or spellings for Leukemia, Myeloid, Philadelphia-Negative:

Myeloid leukemia, Philadelphia-Negative, ALL (Ph- ALL)

 

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