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Diseases » Long QT syndrome » Inheritance

Inheritance and Genetics of Long QT syndrome

Genetics of Long QT syndrome:

Most cases of long QT syndrome are caused by an inherited mutation in one of several genes.

Long QT syndrome: Genetics Information

Genetics of Long QT syndrome: LQTS is usually inherited as an autosomal dominant trait. In the case of LQT1, which has been mapped to chromosome 11, mutations lead to serious structural defects in the person's cardiac potassium channels that do not allow proper transmission of the electrical impulses throughout the heart. There also appear to be other genes, tentatively located on chromosomes 3, 6 and 11 whose mutated products may contribute to, or cause, LQT syndrome. (Source: Genes and Disease by the National Center for Biotechnology)

About inheritance and genetics:

Inheritance of Long QT syndrome refers to whether the condition is inherited from your parents or "runs" in families. The level of inheritance of a condition depends on how important genetics are to the disease. Strongly genetic diseases are usually inherited, partially genetic diseases are sometimes inherited, and non-genetic diseases are not inherited. For general information, see Introduction to Genetics.


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