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Causes of Machado-Joseph Disease

Causes of Machado-Joseph Disease

Machado-Joseph disease is caused by an inherited genetic change in the ataxin-3 gene, ATXN3.

Inheritance of Machado-Joseph Disease

Autosomal dominant diseases are usually inherited from the one parent who already has the disease. Rare cases of sporadic genetic disease with...more »

Machado-Joseph Disease: Related Medical Conditions

To research the causes of Machado-Joseph Disease, consider researching the causes of these these diseases that may be similar, or associated with Machado-Joseph Disease:

Machado-Joseph Disease: Causes and Types

Causes of Broader Categories of Machado-Joseph Disease: Review the causal information about the various more general categories of medical conditions:

What causes Machado-Joseph Disease?

Causes: Machado-Joseph Disease: In Machado-Joseph disease and other spinocerebellar ataxias, degeneration of cells in an area of the brain called the hindbrain leads to deficits in movement. The hindbrain includes the cerebellum, the brainstem, and the upper part of the spinal cord. (Source: excerpt from NINDS Machado-Joseph Disease Information Page: NINDS)

Related information on causes of Machado-Joseph Disease:

As with all medical conditions, there may be many causal factors. Further relevant information on causes of Machado-Joseph Disease may be found in:

 

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