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Macleod-Fraser syndrome is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Macleod-Fraser syndrome, or a subtype of Macleod-Fraser syndrome, affects less than 200,000 people in the US population.
Ophanet, who are a consortium of European partners, currently defines a condition rare when if affects 1 person per 2,000. They list Macleod-Fraser syndrome as a "rare disease". More information about Macleod-Fraser syndrome is available from Orphanet
The term 'prevalence' of Macleod-Fraser syndrome usually refers to the estimated population
of people who are managing Macleod-Fraser syndrome at any given time.
The term 'incidence' of Macleod-Fraser syndrome refers to the annual diagnosis rate,
or the number of new cases of Macleod-Fraser syndrome diagnosed each year.
Hence, these two statistics types can differ:
a short-lived disease like flu can have high annual incidence but low prevalence,
but a life-long disease like diabetes has a low annual incidence but high prevalence.
For more information see about prevalence and incidence statistics.
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