A genetic condition characterized by irregularities in skin pigmentation (café-au-lait spots), bone disease and endocrine (hormone-producing system) problems. The bone diseases can cause bone weakness and deformities in the legs arms and skull. The endocrine disease can cause early puberty and increased rate of growth. Sufferers are affected by the various characteristics of the disease to different degrees - some people may have the condition and have no noticeable problems. ...more »
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FIBROUS DYSPLASIA OF BONE affecting several or many bones. When associated with melanotic pigmentation of the skin and endocrine disorders, it is known as Albright's syndrome. (From Dorland, 28th ed) - (Source - Diseases Database)
McCune-Albright Syndrome is listed as a "rare disease" by the Office of
Rare Diseases (ORD) of the National Institutes of Health
(NIH). This means that McCune-Albright Syndrome, or a subtype of McCune-Albright Syndrome,
affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)
Ophanet, a consortium of European partners,
currently defines a condition rare when it affects 1 person per 2,000.
They list McCune-Albright Syndrome as a "rare disease".
Source - Orphanet
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