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Glossary for Meclofenamate -- Teratogenic Agent

  • Bronchopulmonary dysplasia: A rare form of infant lung disease that usually occurs as a complication of ventilator use in premature babies.
  • Drug-related conditions: Medical conditions related to drug usage, including adverse reactions, intoxication, and overdose.
  • HEM dysplasia: A rare disorder characterized by hydrops, dwarfism and abnormal bone calcification. The condition generally results in fetal death.
  • Leukeran -- Teratogenic Agent: There is evidence to indicate that exposure to Leukeran (a chemotherapy drug) during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Leukomalacia: Softening or destruction of the white matter of the brain. Brain tissue that surrounds fluid-filled parts of the brain (ventricles) is destroyed. It tends to occur mainly in premature or newborn babies who have been deprived of oxygen or have poor blood flow to parts of the brain. Intrauterine infections and premature membrane rupture tend to predispose infants to this condition. This type of brain destruction can cause cerebral palsy. Severity of symptoms varies according to the degree of injury to the brain.
  • Limb reduction defect: A rare congenital malformation where the bones in the arms and/or legs fail to develop normally or are partially or totally missing.
  • Patent ductus arteriosus: Patent ductus arteriosus (PDA) is a congenital heart defect wherein a child's ductus arteriosus fails to close after birth.
  • Pregnancy-related conditions: Any condition that is related to or caused by pregnancy
  • Reduced amniotic fluid: Reduced amniotic fluid is a less than normal quantity of amniotic fluid, which protects and cushions a developing fetus during pregnancy.
  • Teratogen-related conditions: Medical conditions related to "teratogens", i.e. substances that can cause birth defects by fetal exposure.

 

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