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Megaloblastic anemia

Megaloblastic anemia: Introduction

Megaloblastic anemia: A rare blood disorder where insufficient vitamin B12 absorption results in reduced production of red blood cells and increased levels of abnormal, enlarged red blood cells (megaloblasts). Vitamin B12 insufficiency can result from absorption problems or lack of dietary intake of the vitamin or folic acid. More detailed information about the symptoms, causes, and treatments of Megaloblastic anemia is available below.

Symptoms of Megaloblastic anemia

Treatments for Megaloblastic anemia

  • Folate - possibly used for related folate deficiency
  • Treatment involves life-long vitamin B12 injections
  • Lifelong Vitamin B12 supplements are needed - must be injected as the intestines are unable to absorb the vitamin. Excessive protein in the urine will persist despite treatment but does not signal kidney problems.
  • Management of megaloblastic anemia is dependant upon the underlying cause, although many cases will require B12 supplementation. Treatments include:
    • Identification and management of underlying causes - Zollinger-Ellison syndrome, blind loop syndrome, pancreatitis
  • more treatments...»

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Wrongly Diagnosed with Megaloblastic anemia?

Megaloblastic anemia: Related Patient Stories

Megaloblastic anemia: Complications

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Causes of Megaloblastic anemia

  • The genetic anomaly is inherited in an autosomal recessive manner
  • more causes...»

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Disease Topics Related To Megaloblastic anemia

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Less Common Symptoms of Megaloblastic anemia

Megaloblastic anemia: Undiagnosed Conditions

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Misdiagnosis and Megaloblastic anemia

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Megaloblastic anemia: Research Doctors & Specialists

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Hospitals & Clinics: Megaloblastic anemia

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Megaloblastic anemia: Rare Types

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Evidence Based Medicine Research for Megaloblastic anemia

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Megaloblastic anemia: Animations

Research about Megaloblastic anemia

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Statistics for Megaloblastic anemia

Megaloblastic anemia: Broader Related Topics

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Definitions of Megaloblastic anemia:

Anemias associated with impaired DNA synthesis in bone marrow progenitor cells leading to odd shaped, macrocytic, or dysfunctional erythrocytes; usually caused by B12 or folate deficiency. - (Source - Diseases Database)

Anemia characterized by many large immature and dysfunctional red blood cells (megaloblasts) in the bone marrow; associated with pernicious anemia - (Source - WordNet 2.1)

Megaloblastic anemia is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Megaloblastic anemia, or a subtype of Megaloblastic anemia, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

 

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