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Diseases » Meningioma » Wikipedia
 

Meningioma in Wikipedia

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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Meningioma". (Source - Retrieved 2006-09-07 13:59:09 from http://en.wikipedia.org/wiki/Meningioma)

Introduction

Meningiomas are the most common benign tumors of the brain (95% of benign tumors). They arise from the dura mater (outer most layer of the meninges to which the arachnoid mater connects) in the meninges of the brain or the spinal cord and represent about 15% of all primary brain tumors. They are more common in females than in males (2:1) and has a peak incidence in the sixth and seventh decades. Most cases are sporadic while some are familial. There has been some evidence that persons who have undergone radiation to the scalp are more at risk for developing meningiomas. The most frequent genetic mutations involved in meningiomas are inactivation mutations in the neurofibromatosis 2 gene (merlin) on chromosome 22q.

 

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