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Glossary for Microcytic hypochromic anemia

  • Anemia: Reduced ability of blood to carry oxygen from various possible causes.
  • Blood conditions: Conditions that affect the blood
  • Brittle nails: thinning of the nail plate
  • Fatigue: Excessive tiredness or weakness.
  • Lip symptoms: Symptoms affecting one or both lips.
  • Malaise: General feelings of discomfort or being ill-at-ease.
  • Poor appetite: Loss or reduction in appetite for food
  • Pyridoxine -- Teratogenic Agent: There is evidence to indicate that exposure to Pyridoxine during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Sickle Cell Anemia: Sickle cell anemia is an inherited blood disorder characterized by red blood cells which are crescent-shaped rather than the normal doughnut shape. These abnormally shaped red blood cells are unable to function normally and tend to undergo premature destruction which leads to anemia. If the genetic defect which causes the condition is inherited from both parents the condition can be quite severe whereas if it is inherited from only one parent, often there are no symptoms. The abnormally shaped red blood cells can cause problems when they clump together and block blood vessels.
  • Sore mouth: The occurrence of a painful mouth
  • Thalassemia: Thalassemia is an inherited blood disorder characterized by abnormal synthesis of hemoglobin. Hemoglobin consists of two main protein chains called alpha and beta. There are two subtypes of the disorder (alpha and beta) depending on what portion of the hemoglobin is abnormally synthesized. Each of these subtypes can be further classified depending on the number of thalassemia genes involved. A total of four genes is needed to make each ? protein chains and two genes are needed to make each ? chain. The main symptom is anemia, the severity of which can vary amongst patients depending on how many defective genes are involved.

 

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