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Diseases » Microcytosis » Glossary
 

Glossary for Microcytosis

  • Blood conditions: Conditions that affect the blood
  • Chronic Illness: Any form of continuing chronic illness.
  • Debler anemia: A familial type of anemia that starts during infancy and involves the premature destruction of red blood cells.
  • Hemoglobin H: A genetic blood anomaly that causes enlarged liver and spleen and hemolytic anemia.
  • Iron deficiency anemia: Iron-deficiency anemia is a blood condition characterized by low levels of iron in the body which leads to a reduction in the number of red blood cells.
  • Low haemoglobin: Decreased concentration of haemoglobin in the blood.
  • Majeed syndrome: A rare syndrome characterized by blood abnormality and recurring bone infections.
  • Microcytic hypochromic anemia: Microcytic anemia is a blood disorder characterized by small red blood cells (erythrocytes) which have insufficient haemoglobin and hence have a reduced ability to carry oxygen through the body. The red blood cells are small due to a failure of haemoglobin synthesis or insufficient quantities of haemoglobin available. The blood disorder is usually caused by conditions such as iron deficiency, chronic diseases and thalassemias. The severity and range of symptoms is variable.
  • Sickle Cell Anemia: Sickle cell anemia is an inherited blood disorder characterized by red blood cells which are crescent-shaped rather than the normal doughnut shape. These abnormally shaped red blood cells are unable to function normally and tend to undergo premature destruction which leads to anemia. If the genetic defect which causes the condition is inherited from both parents the condition can be quite severe whereas if it is inherited from only one parent, often there are no symptoms. The abnormally shaped red blood cells can cause problems when they clump together and block blood vessels.
  • Sideroblastic anemia, hereditary: An inherited form of anemia where an enzyme deficiency prevents red blood cells from using iron properly. The red blood cells become overloaded with iron which impairs the blood's ability to carry oxygen.
  • Sideroblastic anemia, pyridoxine-responsive, autosomal recessive: Pyridoxine-responsive sideroblastic anemia is a rare inherited blood disorder characterized by abnormal deposits of iron in the red blood cells which makes them unable to function properly. The condition is inherited in an autosomal recessive manner and responds to treatment with pyridoxine.

 

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