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What is Mixed connective tissue disease?

What is Mixed connective tissue disease?

  • Mixed connective tissue disease: A rare disorder of the connective tissue which affects a range of body tissues and organs.
  • Mixed connective tissue disease: A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence.
    Source - Diseases Database

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Mixed connective tissue disease as a "rare disease".
Source - Orphanet

Mixed connective tissue disease: Introduction

Types of Mixed connective tissue disease:

Broader types of Mixed connective tissue disease:

Who gets Mixed connective tissue disease?

Gender Profile for Mixed connective tissue disease: Women 8:1 (NWHIC).

Gender Ratio for Mixed connective tissue disease: female predominance

How serious is Mixed connective tissue disease?

Prognosis of Mixed connective tissue disease: good, 94% survived 6 years after onset
Complications of Mixed connective tissue disease: see complications of Mixed connective tissue disease

What causes Mixed connective tissue disease?

Causes of Mixed connective tissue disease: see causes of Mixed connective tissue disease

What are the symptoms of Mixed connective tissue disease?

Symptoms of Mixed connective tissue disease: see symptoms of Mixed connective tissue disease

Complications of Mixed connective tissue disease: see complications of Mixed connective tissue disease

Onset of Mixed connective tissue disease: adolescence or early adulthood

Can anyone else get Mixed connective tissue disease?

Contagion of autoimmunity: generally not; see details in contagion of autoimmune diseases.

Mixed connective tissue disease: Testing

Misdiagnosis: see misdiagnosis and Mixed connective tissue disease.

How is it treated?

Treatments for Mixed connective tissue disease: see treatments for Mixed connective tissue disease
Research for Mixed connective tissue disease: see research for Mixed connective tissue disease

Name and Aliases of Mixed connective tissue disease

Main name of condition: Mixed connective tissue disease

Class of Condition for Mixed connective tissue disease: autoimmune

Other names or spellings for Mixed connective tissue disease:

Overlap syndrome, Sharp syndrome, MCTD

Sharp's syndrome Source - Diseases Database

Mixed connective tissue disease: Related Conditions

Research the causes of these diseases that are similar to, or related to, Mixed connective tissue disease:

  • Mixed connective tissue disease (MCTD)/Undifferentiated
 

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