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Mixed connective tissue disease in Wikipedia

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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Mixed connective tissue disease". (Source - Retrieved 2006-09-07 14:01:21 from http://en.wikipedia.org/wiki/Mixed_connective_tissue_disease)

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Introduction

Mixed connective tissue disease (MCTD) is a human autoimmune disease in which the immune system attacks the body. MCTD combines features of polymyositis, systemic lupus erythematosus, and systemic scleroderma and is thus considered an overlap syndrome. MCTD commonly causes joint pain/swelling, Raynaud phenomenon, muscle inflammation, and scarring of the skin of the hand. It does not typically cause kidney disease or seizures. Distinguishing laboratory characteristics are a positive, speckled anti-nuclear antibody and an anti-U1-RNP antibody.$[1]$

References

  1. Venables PJ. Mixed connective tissue disease. Lupus. 2006;15(3):132-7. PMID 1663436
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