Assessment
Questionnaire

Have a symptom?
See what questions
a doctor would ask.
 

Types of Mucopolysaccharidoses

Mucopolysaccharidoses: Types list

The list of types of Mucopolysaccharidoses mentioned in various sources includes:

Types discussion:

Eight clinical types and numerous subtypes of mucopolysaccharidoses have been identified. Although each type differs clinically, generally, people with mucopolysaccharidoses experience a period of normal development followed by a decline in physical and/or mental function. Some of the more common types include:

Mucopolysaccharidosis I(MPS I), which includes Hurler, Scheie, and Hurler/Scheie syndromes. Hurler syndrome-the most severe form of the mucopolysaccharidoses -occurs in infancy with symptoms such as clouding of the cornea and progressive physical and mental disability. Death usually occurs before age 10. Patients with Scheie syndrome experience milder symptoms and have normal intelligence, while those with Hurler/Scheie syndrome suffer from intermediate symptoms.

MPS II, also called Hunter syndrome, affects juveniles and includes a mild and a severe form. Signs of the severe form are joint stiffness, mental deterioration, dwarfing, and progressive deafness. Death usually occurs by age 15. Symptoms of the mild form include short stature, limitation of motion, and features such as an enlarged forehead, lips, and tongue and misaligned teeth. Life span may be normal.

Individuals with MPS III, or Sanfilippo syndrome, experience progressive dementia and mental deterioration in childhood. Death usually occurs in the late teens.

Symptoms of MPS IV, or Morquio syndrome, usually appear in infancy and may include severe dwarfing and corneal clouding. Intelligence is normal. Cardiac or respiratory disease may cause death in the third or fourth decade of life. MPS VI, or Maroteauz-Lamy syndrome, resembles Hurler syndrome. Onset is in infancy, however, intelligence is normal. Individuals may live into the second or third decade.

Individuals with MPS VII, Sly disease, experience corneal clouding, skeletal irregularities, and enlargement of the liver and spleen. Intellectual impairments vary for this type of MPS. (Source: excerpt from NINDS Mucopolysaccharidoses Information Page: NINDS)

Mucopolysaccharidoses: Related Disease Topics

More general medical disease topics related to Mucopolysaccharidoses include:

Research More About Mucopolysaccharidoses

 

By using this site you agree to our Terms of Use. Information provided on this site is for informational purposes only; it is not intended as a substitute for advice from your own medical team. The information on this site is not to be used for diagnosing or treating any health concerns you may have - please contact your physician or health care professional for all your medical needs. Please see our Terms of Use.

Home | Symptoms | Diseases | Diagnosis | Videos | Tools | Forum | About Us | Terms of Use | Privacy Policy | Site Map | Advertise