Diseases » Mucopolysaccharidosis I » Introduction

Mucopolysaccharidosis I

Mucopolysaccharidosis I: Introduction

Mucopolysaccharidosis I: Mucopolysaccharidosis I(MPS I), which includes Hurler, Scheie, and Hurler/Scheie syndromes. Hurler syndrome-the most severe form of ... more about Mucopolysaccharidosis I.

Mucopolysaccharidosis I: Disorder of mucopolysaccharide metabolism in infants. More detailed information about the symptoms, causes, and treatments of Mucopolysaccharidosis I is available below.

Symptoms of Mucopolysaccharidosis I

• Clouding of the cornea
• Progressive physical disability
• Progressive mental disability
• Limited joint movement
• Wide mouth
• more symptoms...»

See full list of 19 symptoms of Mucopolysaccharidosis I

Treatments for Mucopolysaccharidosis I

• Symptomatic and supportive
• Enzyme replacement therapy
• more treatments...»

Read more about treatments for Mucopolysaccharidosis I

Wrongly Diagnosed with Mucopolysaccharidosis I?

• Failure to diagnose Mucopolysaccharidosis I
• Undiagnosed: Mucopolysaccharidosis I

Videos for Mucopolysaccharidosis I

See full list of 4 related videos

Mucopolysaccharidosis I: Deaths

Read more about Deaths and Mucopolysaccharidosis I.

Types of Mucopolysaccharidosis I

• Hurler syndrome
• Scheie syndrome - milder symptoms and normal intelligence
• Hurler/Scheie syndrome
• more types...»

Read more about Types of Mucopolysaccharidosis I

Mucopolysaccharidosis I: Complications

Review possible medical complications related to Mucopolysaccharidosis I:

• Compression of spinal cord may lead to neurological problems
• more complications...»

Causes of Mucopolysaccharidosis I

Read more about causes of Mucopolysaccharidosis I.

Disease Topics Related To Mucopolysaccharidosis I

Research the causes of these diseases that are similar to, or related to, Mucopolysaccharidosis I:

• Metabolic disorders
• Lysosomal storage disease
• Carpel tunnel syndrome
• Glaucoma
• Dwarfism
• Mucolipidosis
• Bone dysplasia
• more related diseases...»

Evidence Based Medicine Research for Mucopolysaccharidosis I

Medical research articles related to Mucopolysaccharidosis I include:

• Mucopolysaccharidosis Type 1/Laronidase/a - L
• Mucopolysaccharidosis Type I H/S (Treatment)
• Mucopolysaccharidosis Type IH (Treatment)
• Mucopolysaccharidosis Type IS (Treatment)
• Mucopolysaccharidosis (Treatment)
• Mucopolysaccharidosis (Diagnosis)
• Mucopolysaccharidosis (Follow-up)
• Mucopolysaccharidoses Types I-VII (Follow-up)
• more research...»

Click here to find more evidence-based articles on the TRIP Database

Patient Surveys for Mucopolysaccharidosis I

• Patient Profile Survey
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• Survey about the symptoms of your Mucopolysaccharidosis I
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Prognosis for Mucopolysaccharidosis I

Prognosis for Mucopolysaccharidosis I: Poor. Usually death by age 10.

More about prognosis of Mucopolysaccharidosis I

Research about Mucopolysaccharidosis I

Visit our research pages for current research about Mucopolysaccharidosis I treatments.

Clinical Trials for Mucopolysaccharidosis I

The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.

Some of the clinical trials listed on ClinicalTrials.gov for Mucopolysaccharidosis I include:

• Phase II Study of Allogeneic Bone Marrow or Umbilical Cord Blood Transplantation in Patients With Mucopolysaccharidosis I (Hurler Disease) - This study is currently recruiting patients (Current: 23 Nov 2006) - anti-thymocyte globulin,busulfan,cyclophosphamide,cyclosporine,filgrastim,methylprednisolone
• Study of Pulmonary Complications in Pediatric Patients With Storage Disorders Undergoing Allogeneic Hematopoietic Stem Cell Transplantation - This study is no longer recruiting patients (Current: 23 Nov 2006)
• A Safety Study of Aldurazyme (JC0498 Laronidase) Replacement Therapy in Patients With Mucopolysaccharidosis I (MPS I) Disease - This study is currently recruiting patients (Current: 23 Nov 2006) - Recombinant Human Alpha-L-Iduronidase, Aldurazyme® (laronidase)
• A Phase 4 Study Investigating the Relationship Between the Development of Laronidase Antibody and Urinary GAG Levels in Aldurazyme (Laronidase) Treated Patients. - This study is currently recruiting patients (Current: 23 Nov 2006) - Recombinant Human Alpha-L-Iduronidase, Aldurazyme® (laronidase)
• A Dose-Optimization Study of Aldurazyme (Laronidase) in Patients With Mucopolysaccharidosis I (MPS I) Disease - This study is no longer recruiting patients (Current: 23 Nov 2006) - Aldurazyme (Recombinant Human Alpha-L-Iduronidase)
• more trials...»

See full list of 12 Clinical Trials for Mucopolysaccharidosis I

Statistics for Mucopolysaccharidosis I

• Medical statistics for Mucopolysaccharidosis I
• Prevalence and incidence statistics for Mucopolysaccharidosis I
• Death and Mortality statistics for Mucopolysaccharidosis I
• Society statistics for Mucopolysaccharidosis I

Mucopolysaccharidosis I: Broader Related Topics

• Mucopolysaccharidoses
• Genetic conditions
• Metabolic conditions
• more types...»

Types of Mucopolysaccharidosis I

Mucopolysaccharidosis I Message Boards

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User Interactive Forums

Read about other experiences, ask a question about Mucopolysaccharidosis I, or answer someone else's question, on our message boards:

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Article Excerpts about Mucopolysaccharidosis I

Mucopolysaccharidosis I(MPS I), which includes Hurler, Scheie, and Hurler/Scheie syndromes. Hurler syndrome-the most severe form of the mucopolysaccharidoses -occurs in infancy with symptoms such as clouding of the cornea and progressive physical and mental disability. Death usually occurs before age 10. Patients with Scheie syndrome experience milder symptoms and have normal intelligence, while those with Hurler/Scheie syndrome suffer from intermediate symptoms. (Source: excerpt from NINDS Mucopolysaccharidoses Information Page: NINDS)

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Forums & Message Boards

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