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Multiple endocrine neoplasia type 1

Multiple endocrine neoplasia type 1: Introduction

Multiple endocrine neoplasia type 1: Multiple endocrine neoplasia type 1 (MEN1) is an inherited disorder that affects the endocrine glands. It is sometimes called multiple ... more about Multiple endocrine neoplasia type 1.

Multiple endocrine neoplasia type 1: Rare inherited disease causing tumors in multiple glands. More detailed information about the symptoms, causes, and treatments of Multiple endocrine neoplasia type 1 is available below.

Symptoms of Multiple endocrine neoplasia type 1

Treatments for Multiple endocrine neoplasia type 1

  • Treatment is dependant upon the type of tumor that is present, its location, staging and any hormonal abnormalities that may be present. Treatment includes:
  • Medical management of hormonal abnormalities - often as a temporizing measure before surgery
  • Surgical excision of tumors - mainstay of treatment
  • Chemo and radiotherapy may be utilized in specific circumstances
  • more treatments...»

Home Diagnostic Testing

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Wrongly Diagnosed with Multiple endocrine neoplasia type 1?

Multiple endocrine neoplasia type 1: Related Patient Stories

Multiple endocrine neoplasia type 1: Deaths

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Diagnostic Tests for Multiple endocrine neoplasia type 1

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Multiple endocrine neoplasia type 1: Complications

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Causes of Multiple endocrine neoplasia type 1

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Disease Topics Related To Multiple endocrine neoplasia type 1

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Multiple endocrine neoplasia type 1: Undiagnosed Conditions

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Misdiagnosis and Multiple endocrine neoplasia type 1

Spitz nevi misdiagnosed as dangerous melanoma skin cancer: One possible misdiagnosis to consider in lieu of melanoma is spitz nevi. See melanoma and spitz nevi....read more »

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Multiple endocrine neoplasia type 1: Research Doctors & Specialists

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Hospitals & Clinics: Multiple endocrine neoplasia type 1

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Choosing the Best Hospital: More general information, not necessarily in relation to Multiple endocrine neoplasia type 1, on hospital performance and surgical care quality:

Multiple endocrine neoplasia type 1: Rare Types

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Evidence Based Medicine Research for Multiple endocrine neoplasia type 1

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Prognosis for Multiple endocrine neoplasia type 1

Prognosis for Multiple endocrine neoplasia type 1: Most people with MEN1 will have long and productive lives. (Source: excerpt from Multiple Endocrine Neoplasia Type 1: NIDDK)

Research about Multiple endocrine neoplasia type 1

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Clinical Trials for Multiple endocrine neoplasia type 1

The US based website ClinicalTrials.gov lists information on both federally and privately supported clinical trials using human volunteers.

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Statistics for Multiple endocrine neoplasia type 1

Multiple endocrine neoplasia type 1: Broader Related Topics

Multiple endocrine neoplasia type 1 Message Boards

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Article Excerpts about Multiple endocrine neoplasia type 1

Multiple endocrine neoplasia type 1 (MEN1) is an inherited disorder that affects the endocrine glands. It is sometimes called multiple endocrine adenomatosis or Wermer's syndrome, after one of the first doctors to recognize it. (Source: excerpt from Multiple Endocrine Neoplasia Type 1: NIDDK)

Definitions of Multiple endocrine neoplasia type 1:

The MEN1 gene is a cloned tumor suppressor gene for Multiple Endocrine Neoplasia, a predisposition for endocrine tumors and carcinoid tumors. The gene encodes the tumor suppressor protein MEN1, which regulates transcription through direct interaction with, and inhibition of, transcription factor JunD. Menin also interacts with SMAD3 and appears to be required for SMAD3/4-DNA binding at transcriptional regulatory sites. The human gene is located at 11q13. - (Source - Diseases Database)

Multiple endocrine neoplasia type 1 is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Multiple endocrine neoplasia type 1, or a subtype of Multiple endocrine neoplasia type 1, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list Multiple endocrine neoplasia type 1 as a "rare disease".
Source - Orphanet

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