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Glossary for Mycotoxin-induced liver damage -- Rubratoxin

  • Abdominal conditions: Medical conditions affecting the abdominal region.
  • Abdominal pain: A condition which is characterized by the sensation of pain that is located in the abdomen
  • Cholestyramine -- Teratogenic Agent: There is evidence to indicate that exposure to Cholestyramine (cholesterol-lowering drug) during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Conditions involving a pathogen: Medical conditions involving some type of pathogen, such as a virus or bacteria.
  • Diarrhea: Loose or watery stool.
  • Digestive Diseases: Diseases that affect the digestive system
  • Fungal infections: Any condition caused by fungus.
  • Hepatotoxicity: Damage or injury to the liver caused by a drug, chemical or other agent. Symptoms vary depending on the degree of exposure and hence extent of the liver damage or injury. Mild liver damage may cause few if any symptoms whereas severe damage can ultimately result in liver failure.
  • Liver cancer: Hepatocellular carcinoma (HCC) is a primary malignancy of the liver.
  • Liver conditions: Any condition that affects the liver
  • Liver failure: Acute liver failure (ALF) is an uncommon condition in which the rapid deterioration of liver function results in coagulopathy and alteration in the mental status of a previously healthy individual.
  • Mycotoxin-induced liver damage -- Sterigmatocystin: Damage or injury to the liver caused by exposure to a Mycotoxin called Sterigmatocystin. It is a toxin produced by a particular fungus (Aspergillus). Sterigmatocystin may also increase the risk of developing liver cancer. Most likely sources of exposure are foods such as wheat, maize, hard cheese and green coffee beans contaminated with mould. Symptoms vary depending on the degree of exposure and hence extent of the liver damage or injury. Mild liver damage may cause few if any symptoms whereas severe damage can ultimately result in liver failure. Symptoms may be acute, subacute or chronic depending on the severity of the exposure. Factors such as age, race, gender, overall health and underlying liver problems may also influence a person's risk of developing liver problems and the severity of the symptoms. The toxin is also know to increase the risk of developing liver cancer.
  • Nausea: The queasy feeling of nausea and often also vomiting.
  • No symptoms: The absence of noticable symptoms.
  • Poor appetite: Loss or reduction in appetite for food
  • Tiredness: Feeling tired either physically or mentally
  • Ursodeoxycholic Acid -- Teratogenic Agent: There is evidence to indicate that exposure to Ursodeoxycholic Acid during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Vomiting: Vomiting or retching symptoms.
  • Weakness: Symptoms causing weakness of the body

 

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