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Diseases » Myeloma » Glossary
 

Glossary for Myeloma

  • Amyloidosis: A rare group of metabolic disorders where a protein called amyloid accumulates in body organs and tissues where it can cause damage and is potentially fatal. Symptoms depend on the organs involved. There are numerous forms of the condition: primary amyloidosis, secondary amyloidosis, hemodialysis-associated amyloidosis and familial amyloidosis.
  • Amyloidosis AL: A disease involving the abnormal deposit of amyloid fibrils in virtually any part of the body - the heart, liver, kidney and peripheral and autonomic nerves are most commonly affected. The abnormal amyloid fibrils are produced abnormal plasma cells in the bone marrow. In some cases, the excess growth of abnormal plasma cells can result in a cancerous condition called myeloma resulting in bone pain and infections. A patient with myeloma may develop amyloidosis but it is rare for a patient with AL amyloidosis to go on to develop myeloma.
  • Bence jones protein: Bence Jones protein is a type of abnormal protein that may be found in the urine associated with certain conditions and diseases that produce high levels of protein in the urine.
  • Bleeding symptoms: Any type of bleeding symptoms.
  • Blood cancer: Malignancy of one or several of the different types of cells in the blood
  • Blood conditions: Conditions that affect the blood
  • Bone Marrow Conditions: Medical conditions affecting the bone marrow
  • Bone pain: Bone pain or tenderness is aching or other discomfort in one or more bones.
  • Cachexia: physical wasting with loss of weight and muscle mass caused by disease
  • Cancer: Abnormal overgrowth of body cells.
  • Carpal Tunnel Syndrome: Hand or wrist problems; often from repetitive motion.
  • Fatigue: Excessive tiredness or weakness.
  • Glomerulonephritis: Kidney disease where the kidney's have problems removing waste material and excessive fluid.
  • Human carcinogen -- Melphalan: Melphalan (a chemotheraphy drug) is deemed to be carcinogenic to humans. The carcinogenicity of the substance may be influenced by duration and level of exposure.
  • Interstitial nephritis: A condition which is characterized by disease of the renal interstitial tissue
  • Kyphosis: Outward curvature of the spine at the back causing hunching or Dowager's hump
  • Lymphocytosis: An abnormal increase in the number of lymphocytes in the blood.
  • Monoclonal gammopathy of undetermined significance: A rare condition characterized by the presence of an abnormal protein in the blood. The condition can occasionally lead to cancers such as myeloma so careful monitoring is recommended.
  • Multiple Myeloma: A rare malignant cancer that occurs in the bone marrow. More common in skull, spine, rib cage, pelvis and legs.
  • Osteoporosis: Bone thinning and weakening from bone calcium depletion.
  • Peripheral neuropathy: Peripheral neuropathy is the term for damage to nerves of the peripheral nervous system, which may be caused either by diseases of the nerve or from the side-effects of systemic illness.
  • Probable human carcinogen -- Adriamycin: Adriamycin (a chemotherapy drug) is a substance deemed to be a probable carcinogen to humans. The carcinogenicity of the substance may be influenced by the duration and level of exposure.
  • Pyoderma Gangrenosum: A rare inflammatory skin disorder characterized by small red bumps or blisters which eventually become ulcerated.
  • Raynaud's phenomenon: Blood vessel constriction attacks affecting fingers and/or toes.
  • Thalidomide -- Teratogenic Agent: There is evidence to indicate that exposure to Thalidomide during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Thrombocytopenia: Decreased platelets in the blood
  • Vincristine -- Teratogenic Agent: There is evidence to indicate that exposure to Vincristine during pregnancy and even the during the year leading up to the pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Weakness: Symptoms causing weakness of the body
  • Weight loss: Loss of body weight.

 

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