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Treatments for Myoclonus

Treatment List for Myoclonus

The list of treatments mentioned in various sources for Myoclonus includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.

Myoclonus: Is the Diagnosis Correct?

The first step in getting correct treatment is to get a correct diagnosis. Differential diagnosis list for Myoclonus may include:

Hidden causes of Myoclonus may be incorrectly diagnosed:

Myoclonus: Marketplace Products, Discounts & Offers

Products, offers and promotion categories available for Myoclonus:

Myoclonus: Research Doctors & Specialists

Research all specialists including ratings, affiliations, and sanctions.

Hospital statistics for Myoclonus:

These medical statistics relate to hospitals, hospitalization and Myoclonus:

  • 0.004% (471) of hospital consultant episodes were for myoclonus in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 86% of hospital consultant episodes for myoclonus required hospital admission in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 44% of hospital consultant episodes for myoclonus were for men in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • 56% of hospital consultant episodes for myoclonus were for women in England 2002-03 (Hospital Episode Statistics, Department of Health, England, 2002-03)
  • more hospital information...»

Discussion of treatments for Myoclonus:

NINDS Myoclonus Information Page: NINDS (Excerpt)

Treatment for myoclonus consists of medications that may help reduce symptoms. Many of these drugs, which include barbiturates, clonazepam, phenytoin, primidone, and sodium valproate, are also used to treat epilepsy. The complex origins of myoclonus may require the use of multiple drugs for effective treatment. (Source: excerpt from NINDS Myoclonus Information Page: NINDS)

Myoclonus Fact Sheet: NINDS (Excerpt)

Treatment of myoclonus focuses on medications that may help reduce symptoms. The drug of first choice to treat myoclonus, especially certain types of action myoclonus, is clonazepam, a type of tranquilizer. Dosages of clonazepam usually are increased gradually until the patient improves or side effects become harmful. Drowsiness and loss of coordination are common side effects. The beneficial effects of clonazepam may diminish over time if the patient develops a tolerance for the drug.

Many of the drugs used for myoclonus, such as barbiturates, phenytoin, and primidone, are also used to treat epilepsy. Barbiturates slow down the central nervous system and cause tranquilizing or antiseizure effects. Phenytoin and primidone are effective antiepileptic drugs, although phenytoin can cause liver failure or have other harmful long-term effects in patients with PME. Sodium valproate is an alternative therapy for myoclonus and can be used either alone or in combination with clonazepam. Although clonazepam and/or sodium valproate are effective in the majority of patients with myoclonus, some people have adverse reactions to these drugs.

Some studies have shown that doses of 5-hydroxytryptophan (5-HTP), a building block of serotonin, leads to improvement in patients with some types of action myoclonus and PME. However, other studies indicate that 5-HTP therapy is not effective in all people with myoclonus, and, in fact, may worsen the condition in some patients. These differences in the effect of 5-HTP on patients with myoclonus have not yet been explained, but they may offer important clues to underlying abnormalities in serotonin receptors.

The complex origins of myoclonus may require the use of multiple drugs for effective treatment. Although some drugs have a limited effect when used individually, they may have a greater effect when used with drugs that act on different pathways or mechanisms in the brain. By combining several of these drugs, scientists hope to achieve greater control of myoclonic symptoms. Some drugs currently being studied in different combinations include clonazepam, sodium valproate, piracetam, and primidone. Hormonal therapy also may improve responses to antimyoclonic drugs in some people. (Source: excerpt from Myoclonus Fact Sheet: NINDS)

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